Thymoma originating from the cervical component of the thymus in a degu

2021 ◽  
pp. 104063872110456
Author(s):  
Naka Okumura ◽  
Hirotaka Kondo ◽  
Shinichi Suzuki ◽  
Hisashi Shibuya
Keyword(s):  
Rodent Species ◽  
Thoracic Wall ◽  
Thymic Tissue ◽  
Octodon Degus ◽  
Ventral Aspect ◽  
Subcutaneous Mass ◽  
The Right ◽  
Cervical Area

A 5-y-old, male degu ( Octodon degus) was presented with a subcutaneous mass in the ventral aspect of the cervical area. The mass was removed surgically. Histologically, the mass was a densely cellular, expansile neoplasm, with compression of thymic tissue to the periphery. The neoplasm consisted of solid sheets of polygonal cells, mixed with fewer small lymphocytes. Rare Hassall bodies were scattered throughout the mass. Polygonal cells were positive for anti-keratin/cytokeratin AE1/AE3 antibody, and small lymphocytes were positive for anti-CD3 antibody. The histopathologic and immunohistochemical findings were consistent with a thymoma. In addition, an autopsy revealed myxosarcoma of the right thoracic wall with metastasis to the lung. To our knowledge, thymoma originating from the cervical component of the thymus has not been documented previously in a rodent species.

Chalastospora gossypii in a Maine Coon cat: case report and literature review

2021 ◽  
pp. 104063872110222
Author(s):  
Samantha M. Norris ◽  
Paula A. Schaffer ◽  
Noah B. Bander
Keyword(s):  
Soft Tissue ◽  
Needle Aspiration ◽  
Tissue Mass ◽  
Large Numbers ◽  
Formalin Fixed Paraffin ◽  
Formalin Fixed Paraffin Embedded ◽  
Soft Tissue Masses ◽  
Subcutaneous Mass ◽  
The Right ◽  
A Minor

A 15-y-old castrated male Maine Coon cat was evaluated for an ulcerated soft tissue mass on the right hindlimb that had been observed for 4 mo and had grown rapidly. A 3 × 3 cm soft, raised, amorphous, and ulcerated subcutaneous mass was observed on the lateral right metatarsus. In-house cytology via fine-needle aspiration was nondiagnostic. Incisional biopsy of the mass and further staging was declined, and amputation was elected. The amputated limb was submitted for histopathology, which revealed severe chronic nodular granulomatous dermatitis and multifocal granulomatous popliteal lymphadenitis with large numbers of intralesional fungal hyphae. Fungal PCR and sequencing on formalin-fixed, paraffin-embedded tissue identified Chalastospora gossypii. No adjunctive therapy was elected at the time. The patient has done well clinically 1 y post-operatively. C. gossypii is a rare microfungus found worldwide and is considered a minor pathogen of several plants. To our knowledge, infection by this fungus has not been reported previously in veterinary species. Features in our case are comparable to other mycotic infections. Nodular granulomatous mycotic dermatitis and cellulitis, although uncommon, should be a differential for soft tissue masses in veterinary species; C. gossypii is a novel isolate.

scholarly journals A Case of Multiple Posterior Intercostal Artery Common Trunks in Conjunction with Additional Arterial Variations

2021 ◽  
Vol 2021 ◽  
pp. 1-7
Author(s):  
Nicholas R. Fanselow ◽  
Nolan Wallace ◽  
Daniel Sehi ◽  
Lokesh Coomar ◽  
John Martin ◽  
...  
Keyword(s):  
Vertebral Artery ◽  
Intercostal Space ◽  
Thoracic Wall ◽  
Thoracic Cavity ◽  
Arterial Variation ◽  
Arterial Variations ◽  
First Case ◽  
Male Cadaver ◽  
The Right ◽  
High Level

Several thoracic vasculature variations were observed in an 81-year-old male cadaver during routine dissection. These included 5 common trunks of posterior intercostal arteries, a descending branch of the right vertebral artery, and atypical neurovascular relationships within intercostal spaces. On the right side, two common trunks of posterior intercostal arteries were observed supplying the 4th-7th intercostal spaces and 9th-11th intercostal spaces, respectively. There was also a small accessary branch supplying the 9th intercostal space. The first three posterior intercostal spaces on the right were supplied by a descending branch of the vertebral artery. On the left side, three common trunks of posterior intercostal arteries were encountered, supplying intercostal spaces 3-5, 6-7, and 11 plus the subcostal space. An atypical neurovascular relationship was observed in the right 6th intercostal space, as well as the left 2nd, 3rd, and 6th intercostal spaces. This is the first case report that presents 5 common trunks of posterior intercostal arteries, as well as common trunks in conjunction with other arterial variation in the posterior thoracic wall. These variations carry a high level of clinical significance and may be helpful in guiding decision-making related to surgical procedures related to the posterior thoracic cavity and spine.

Cytomorphologic findings of thyroid carcinoma showing thymus-like (CASTLE) differentiation: A case report

2021 ◽  
Vol 156 (Supplement_1) ◽  
pp. S42-S42
Author(s):  
A K Abu-Salah ◽  
S Segura ◽  
H Mesa ◽  
H M Cramer
Keyword(s):  
Case Report ◽  
Thyroid Carcinoma ◽  
Thymic Carcinoma ◽  
Needle Aspiration ◽  
Central Neck Dissection ◽  
Anaplastic Carcinoma ◽  
Thyroid Neoplasm ◽  
Squamous Differentiation ◽  
Thymic Tissue ◽  
The Right

Abstract Introduction/Objective Thyroid carcinoma showing thymus-like differentiation also known as intrathyroidal thymic carcinoma is a rare thyroid neoplasm arising from either an ectopic intrathyroidal thymic tissue or from remnants of thymobranchial pouches. On fine needle aspiration (FNA) its diagnosis can be challenging due to overlapping morphologic features with other aggressive thyroid carcinomas. Methods/Case Report A 31-year-old female consulted for 6-month history of neck swelling and tenderness. Thyroid ultrasound demonstrated a 2.6 x 2.5 x 2.1 cm nodule in the right lobe with punctate calcifications. FNA showed cellular smears composed of loosely cohesive and single basaloid neoplastic cells exhibiting significant cellular and nuclear pleomorphism. Focal squamous differentiation with keratinization was noted on the cell block sections. Immunocytochemical stains showed that the tumor was positive for cytokeratin AE1/AE3, p40, p63, CD117 and CD5 consistent with intrathyroidal thymic carcinoma. The Ki67 proliferative index was approximately 40%. A right thyroidectomy with central neck dissection confirmed the diagnosis and showed a 3.0 cm tumor with invasion into skeletal muscle, lymphovascular invasion and positive lymph nodes. The patient completed adjuvant radiotherapy and remain in remission at 3-months follow-up. Results (if a Case Study enter NA) NA Conclusion Intrathyroidal thymic carcinoma is a rare thyroid neoplasm that frequently shows squamous differentiation and therefore overlaps with papillary thyroid carcinoma with squamous morulae, squamous cell carcinoma and anaplastic carcinoma. The coexpression of squamous markers together with CD5 and CD117 allows the recognition of CASTLE on FNA samples.

scholarly journals Subcutaneous herniation of fetuses after blunt force trauma in a cat

2020 ◽  
Vol 6 (2) ◽  
pp. 205511692094657
Author(s):  
Alexandra G Collins-Webb ◽  
Ashley L Hanna ◽  
Lea R Mehrkens ◽  
Daniel J VanderHart
Keyword(s):  
Abdominal Wall ◽  
Soft Tissues ◽  
Motor Vehicle ◽  
Uterine Horn ◽  
Thoracic Wall ◽  
Whole Body ◽  
Gravid Uterus ◽  
Blunt Force ◽  
Blunt Force Trauma ◽  
The Right

Case summary A stray female domestic shorthair cat was presented to the emergency service after being hit by a car. The patient was recumbent and vocalizing, with a small wound over the right lateral thorax, and two palpably firm swellings in the right cervical and thoracic soft tissues. The patient was sedated and humanely euthanized to prevent further pain and suffering. Post-mortem whole-body radiographs and subsequent necropsy revealed abdominal wall rupture with herniation of two near-term fetuses within the subcutaneous tissues along the right ventrolateral thoracic wall and neck. Within the abdomen, the right uterine horn was ruptured and a third extra-luminal fetus was identified. The left uterine horn remained intact, containing a fourth fetus. Relevance and novel information Rupture of the abdominal wall or diaphragm are well-known potential complications of blunt force trauma, such as motor vehicle accidents. While traumatic uterine rupture and diaphragmatic herniation of the gravid uterus have both been reported in the veterinary literature, abdominal wall rupture with subcutaneous fetal herniation is highly uncommon.

scholarly journals Cutaneous mastocytoma with eosinophilia and eosinophilic infiltration of the small intestine in an Arabian gelding

2020 ◽  
Vol 8 (1) ◽  
pp. e000773
Author(s):  
Natasha Jane Williams ◽  
Robin van den Boom
Keyword(s):  
Small Intestine ◽  
Tendon Sheath ◽  
Needle Aspiration ◽  
Eosinophilic Infiltration ◽  
Mesenteric Root ◽  
Flexor Tendon Sheath ◽  
Subcutaneous Mass ◽  
Small Intestinal ◽  
The Right ◽  
The University

A 12-year-old Arabian gelding presented to the University of Adelaide for investigation of a firm subcutaneous mass, just proximal to the digital flexor tendon sheath of the right forelimb, that had appeared two weeks prior. The skin overlying the mass was intact. Fine needle aspiration identified eosinophilic and mastocytic infiltrates. One week later, the gelding re-presented for persistent colic signs. Blood examination showed eosinophilia, and on palpation per rectum the mesenteric root was very firm and enlarged and a number of small intestinal loops had subjectively thickened walls. Colic signs were unabated by the administration of pain relief. The owner declined surgery and the gelding was euthanased. Postmortem examination confirmed a diagnosis of cutaneous mastocytoma and revealed eosinophilic infiltration of the small intestine.

scholarly journals Helminthic infection in three native rodent species from a semiarid Mediterranean ecosystem

2019 ◽  
Vol 28 (1) ◽  
pp. 119-125 ◽  
Author(s):  
Andrea Yáñez-Meza ◽  
Carlos Landaeta-Aqueveque ◽  
Nicol Quiroga ◽  
Carezza Botto-Mahan
Keyword(s):  
Prevalence Rate ◽  
Rodent Species ◽  
Mediterranean Ecosystem ◽  
Helminth Parasites ◽  
Octodon Degus ◽  
Gastrointestinal Helminth ◽  
Helminthic Infection ◽  
Low Diversity ◽  
Parasitic Load ◽  
Low Prevalence

Abstract Helminth parasites are still not a well-known component of animal biodiversity. In this study, we describe and compare the endoparasite assemblages of three native rodent species from a semiarid Mediterranean ecosystem. A total of eight species of gastrointestinal helminth parasites were detected. The endoparasitic communities of the rodents Phyllotis darwini (5 species), Octodon degus (4 species), and Abrothrix olivaceus (3 species) were described in terms of their prevalence and mean abundance. In addition, endoparasite records by rodent species were submitted to rarefaction analyses to verify sampling robustness and used to compare richness and similarity among rodent species. O. degus presented the highest prevalence and parasitic load, but was of low diversity, while P. darwini presented the highest diversity, but had a low prevalence rate. Conversely, A. olivaceus presented the lowest prevalence and diversity. This study contributes to the existing knowledge of the endoparasitic fauna of rodent species from semiarid Mediterranean zones.

scholarly journals Mantle Cell Lymphoma Presenting as a Subcutaneous Mass of the Right Leg

2020 ◽  
Vol 13 (2) ◽  
pp. 774-782
Author(s):  
Drew A. Fajardo ◽  
Joel France ◽  
Bogna I. Targonska ◽  
H. Bobby Kahlon ◽  
Max J. Coppes
Keyword(s):  
Bone Marrow ◽  
Mantle Cell Lymphoma ◽  
Cell Lymphoma ◽  
Bone Marrow Involvement ◽  
Non Hodgkin Lymphoma ◽  
Mantle Cell ◽  
History Of ◽  
Subcutaneous Mass ◽  
Systemic Symptoms ◽  
The Right

Mantle cell lymphoma (MCL) is a relatively rare B-cell non-Hodgkin lymphoma, typically presenting with extensive lymphadenopathy, bone marrow involvement, and splenomegaly. Extranodal sites can also be involved. We discuss a 73-year-old man whose MCL presented with a 6-month history of a subdermal mass of the right upper thigh and no systemic symptoms.

scholarly journals Recurrent Intrathoracic Locking of the Scapula after Lung Cancer Resection and Combined Rib Resection

2017 ◽  
Vol 2017 ◽  
pp. 1-4
Author(s):  
Akinori Kimura ◽  
Hideyuki Sasanuma ◽  
Takashi Ajiki ◽  
Hitoshi Sekiya ◽  
Katsushi Takeshita
Keyword(s):  
Lung Cancer ◽  
Spindle Cell ◽  
Three Dimensional ◽  
Spindle Cell Carcinoma ◽  
Primary Lesion ◽  
Thoracic Wall ◽  
Advanced Lung Cancer ◽  
Lung Lobectomy ◽  
Thoracic Wall Resection ◽  
The Right

We report a case of recurrent locking of the scapula in the thorax after combined lobectomy and thoracic wall resection for advanced lung cancer. The patient was a 52-year-old man with advanced spindle cell carcinoma in his right lung. He had undergone right lung lobectomy and thoracic wall excision (Th1–5). Intrathoracic repair had not been performed to address the defect in the thoracic wall. Two months after the operation he experienced sudden acute pain in the right shoulder. Three-dimensional computed tomography revealed locking of the scapula intrathoracically. The diagnosis was recurrent locking of the scapula in the thorax. He underwent conservative treatment. Because his symptoms were not alleviated and he continued to experience recurrent locking, we performed partial resection of the inferior part of the scapula. Although scapular locking diminished after this procedure, there were still some pain and “catching” between the scapula and the thoracic wall (T6) when he undertook certain movements. No further surgery could be performed, however, because the cancer from the primary lesion had recurred near the previously operated thoracic wall. A procedure for recurrent intrathoracic locking of the scapula was not successful in this case.

Claudin-5-positive angioleiomyoma in the uterus of a degu ( Octodon degus )

2010 ◽  
Vol 58 (3) ◽  
pp. 331-340 ◽  
Author(s):  
Csaba Jakab ◽  
Miklós Rusvai ◽  
Nóra Biró ◽  
Zoltán Szabó ◽  
Péter Gálfi ◽  
...  
Keyword(s):  
Endothelial Cells ◽  
Immunohistochemical Analysis ◽  
Positive Control ◽  
Histopathological Diagnosis ◽  
Mesenchymal Tumour ◽  
Tissue Mass ◽  
Octodon Degus ◽  
Internal Positive Control ◽  
The Right ◽  
Endothelial Marker

A 5-year-old female degu ( Octodon degus ) showed the clinical sign of metrorrhagia. During ovariohysterectomy a circumscribed tumoural lesion was found in the right uterine horn. The histopathological diagnosis of this soft tissue mass was primary benign cavernous angioleiomyoma of the uterus. During immunohistochemical analysis the neoplastic endothelial cells of this mixed mesenchymal tumour showed strong membrane positivity for the endothelial marker claudin-5 but were negative for CD31 (another endothelial marker). The endothelial cells of the internal positive control tissues such as intact peritumoural vessels were positive for claudin-5 but negative for the CD31 endothelial marker. As it has been described also in other species, it seems that claudin-5 is a better endothelial marker than CD31 for the detection of normal and neoplastic endothelial cells in different tissues of degus.

scholarly journals Unusual Pharyngo-Esophageal Dysphagia Caused by a High-Riding Right Brachiocephalic Artery

2021 ◽  
Vol 45 (1) ◽  
pp. 79-82
Author(s):  
Ki Hoon Park ◽  
Sora Baek ◽  
Eun Kyoung Kang
Keyword(s):  
Filling Defect ◽  
Neck Mass ◽  
Solid Food ◽  
Brachiocephalic Artery ◽  
Food Bolus ◽  
Videofluoroscopic Swallowing Study ◽  
Esophageal Dysphagia ◽  
Left Neck ◽  
The Right ◽  
Cervical Area

High-riding right brachiocephalic and subclavian arteries are often asymptomatic and rare vascular variations. We present a patient with high-riding right brachiocephalic and subclavian arteries that caused compressive pharyngeal and cervical esophageal dysphagia. An 82-year-old woman presented to our hospital with dysphagia that worsened with solid food. A pulsatile lump was observed on the right neck side. A videofluoroscopic swallowing study showed a deviated food bolus movement anterolaterally from the normal vertical pharyngoesophageal transition, with a filling defect in the lower pharynx through the upper esophagus. Neck computed tomography (CT) showed high-riding right brachiocephalic and subclavian arteries and a tortuous right common carotid artery located adjacent to the trachea in the cervical area. The cervical midline structures were deviated to the left neck side. A neck mass with vascular variation should be considered as a cause of dysphagia that worsens with solid food; CT should be considered to determine its cause.

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