scholarly journals Recurrent Intrathoracic Locking of the Scapula after Lung Cancer Resection and Combined Rib Resection

2017 ◽  
Vol 2017 ◽  
pp. 1-4
Author(s):  
Akinori Kimura ◽  
Hideyuki Sasanuma ◽  
Takashi Ajiki ◽  
Hitoshi Sekiya ◽  
Katsushi Takeshita
Keyword(s):  
Lung Cancer ◽  
Spindle Cell ◽  
Three Dimensional ◽  
Spindle Cell Carcinoma ◽  
Primary Lesion ◽  
Thoracic Wall ◽  
Advanced Lung Cancer ◽  
Lung Lobectomy ◽  
Thoracic Wall Resection ◽  
The Right

We report a case of recurrent locking of the scapula in the thorax after combined lobectomy and thoracic wall resection for advanced lung cancer. The patient was a 52-year-old man with advanced spindle cell carcinoma in his right lung. He had undergone right lung lobectomy and thoracic wall excision (Th1–5). Intrathoracic repair had not been performed to address the defect in the thoracic wall. Two months after the operation he experienced sudden acute pain in the right shoulder. Three-dimensional computed tomography revealed locking of the scapula intrathoracically. The diagnosis was recurrent locking of the scapula in the thorax. He underwent conservative treatment. Because his symptoms were not alleviated and he continued to experience recurrent locking, we performed partial resection of the inferior part of the scapula. Although scapular locking diminished after this procedure, there were still some pain and “catching” between the scapula and the thoracic wall (T6) when he undertook certain movements. No further surgery could be performed, however, because the cancer from the primary lesion had recurred near the previously operated thoracic wall. A procedure for recurrent intrathoracic locking of the scapula was not successful in this case.

scholarly journals Medical Image of the Month: Metastatic Spindle Cell Carcinoma of the Breast

2021 ◽  
Vol 22 (6) ◽  
pp. 114-115
Author(s):  
Vinita Kusupati ◽  
◽  
Stefano Natali
Keyword(s):  
Emergency Room ◽  
Spindle Cell ◽  
Work Of Breathing ◽  
Spindle Cell Carcinoma ◽  
Thoracic Wall ◽  
Bilateral Mastectomy ◽  
Primary Malignancy ◽  
The Past ◽  
Breath Sounds ◽  
The Right

No abstract available. Article truncated after 150 words. Clinical Scenario: A 71-year-old woman with primary malignancy of the breast in remission post bilateral mastectomy in 2005 and 2008, presented to the emergency room with progressive shortness of breath for the past 6 months. Upon arrival to the emergency room, she described localized sharp chest pain along the right thoracic wall which had gradually worsened over the past three months. The pain was exacerbated with movement and with deep inspiration. She also endorsed significant hemoptysis, expectorating approximately 500 ml of bloody sputum on the morning of her presentation. Pertinent vitals revealed that she was both tachycardic and tachypneic, saturating 94% on room air with an increased work of breathing. Physical examination was significant for coarse breath sounds and diminished right sided lung sounds. Initial labs demonstrated a normal troponin and an unremarkable EKG. A chest radiograph demonstrated a large left mediastinal and hilar mass with numerous parenchymal nodules bilaterally. …

scholarly journals Surgical Pathology of Combined Thoracic Wall Resection in Lung Cancer

Haigan ◽  
1978 ◽  
Vol 18 (4) ◽  
pp. 371-379
Author(s):  
Hisao Mishina ◽  
Keiichi Suemasu ◽  
Takeshi Yoneyama ◽  
Tsuguo Naruke ◽  
Toshiro Ogata ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Surgical Pathology ◽  
Thoracic Wall ◽  
Thoracic Wall Resection

Stereotactic body radiation therapy (SBRT) in the management of pulmonary spindle cell carcinoma

2020 ◽  
Vol 13 (4) ◽  
pp. e234779 ◽  
Author(s):  
Moyosore D Awobajo ◽  
Ara A Vaporciyan ◽  
Charles Lu ◽  
Saumil J Gandhi
Keyword(s):  
Radiation Therapy ◽  
Cell Carcinoma ◽  
Stereotactic Body Radiation Therapy ◽  
Spindle Cell ◽  
Primary Tumour ◽  
Spindle Cell Carcinoma ◽  
Ct Guided ◽  
Stereotactic Body Radiation ◽  
Positron Emission ◽  
The Right

A 69-year-old woman underwent routine screening with CT scan of the chest, which showed a new right upper lobe lesion. Interval increase in size of the right upper lobe nodule over 3 months, prompted a CT-guided biopsy of the lung that confirmed a diagnosis of malignant pulmonary spindle cell carcinoma (PSCC) with 90% programmed death ligand 1 expression. Positron emission tomography CT demonstrated localised stage IIA disease. Given histologically proven PSCC and the rapid growth of her tumour, curative radiation with stereotactic body radiation therapy (SBRT) to the right upper lobe primary tumour was planned as patient was deemed not to be a surgical candidate. Repeat imaging with a CT chest 2 months after SBRT demonstrated good local control of the primary disease in the right upper lobe despite rapidly advancing distant metastasis. The patient continues systemic therapy with pembrolizumab, to which she has shown good response.

scholarly journals HER2-Positive Metaplastic Spindle Cell Carcinoma Associated with Synchronous Bilateral Apocrine Carcinoma of the Breast

2014 ◽  
Vol 2014 ◽  
pp. 1-5
Author(s):  
Katsumi Kito ◽  
Toshiharu Maeda ◽  
Keiko Ninomiya ◽  
Atsuro Sugita ◽  
Teiri Sagawa ◽  
...  
Keyword(s):  
Cell Carcinoma ◽  
Spindle Cell ◽  
Spindle Cell Carcinoma ◽  
Metaplastic Carcinoma ◽  
Apocrine Carcinoma ◽  
Her2 Positive ◽  
First Case ◽  
Spindle Cell Lesion ◽  
Apocrine Differentiation ◽  
The Right

Apocrine carcinoma, which is strictly defined as over 90% of tumor cells showing apocrine differentiation, is a rare variant of breast cancer. Here we report an uncommon case in which apocrine carcinomas developed concurrently in both breasts; in addition, a sarcomatoid spindle cell lesion was coincident in the right breast. Both apocrine carcinomas were immunohistochemically negative for estrogen receptor (ER) and progesterone receptor (PgR), but diffusely positive for androgen receptor (AR), GCDFP-15, and HER2. The presence of intraductal components in bilateral carcinomas and the absence of lymph node metastasis suggested that they were more likely to be individual primary lesions rather than metastatic disease. The spindle cell lesion showed a relatively well-circumscribed nodule contiguous with the apocrine carcinoma. HER2 oncoprotein overexpression was observed not only in the apocrine carcinoma, but also in the spindle cell lesion. Since the spindle cell component was intimately admixed with apocrine carcinoma and had focal cytokeratin expression, we diagnosed it as metaplastic spindle cell carcinoma, which was originated from the apocrine carcinoma. To our knowledge, this is the first case report of a patient with synchronous bilateral apocrine carcinomas coinciding with metaplastic carcinoma.

scholarly journals SPINDLE CELL CARCINOMA OF LARYNX- A DISTINCT CLINICOPATHOLOGICAL AND HISTOLOGICAL ENTITY

2017 ◽  
Vol 3 (3) ◽  
Author(s):  
Muhammad Faisal ◽  
Arif Jamshed ◽  
Raza Hussain
Keyword(s):  
Risk Factors ◽  
Cell Carcinoma ◽  
Vocal Cord ◽  
Distant Metastasis ◽  
Spindle Cell ◽  
Spindle Cell Carcinoma ◽  
Treatment Result ◽  
Left Vocal Cord ◽  
History Of ◽  
The Right

Spindle cell carcinoma (SpCC) is a variant of squamous cell carcinoma with biphasic components and more aggressive behaviour. Its rarity and histopathological pattern pose a diagnostic challenge. Early diagnosis and treatment result in a decrease in local and distant metastasis. Case 1 is a 71-year-old female presented with hoarseness of voice and dyspnoea for 2 years without any risk factors. Fibre-optic laryngoscopy (FOL) revealed smooth polyp hanging from anterior two-third of the left vocal cord. Microlaryngoscopic excision revealed SpCC followed by post-operative radiotherapy and is currentlyalive. Case 2 is a 72-year-old male presented with worsening stridor for 2 years post-excision of laryngeal nodule and history of smoking and hookah use for >20 years. He developed dysphonia after a few months with fixed hard level 3 nodes at the right side. FOL showed a polypoid mass extending from the left vocal cord into the supraglottis. Fine-needle aspiration cytology of the neck swelling confirmed the diagnosis of SpCC. Computerised tomography (CT) chest/abdomen showed distant metastasis. Palliative radiotherapy was given, but the patient died after 3 months due to locoregional failure. Case 3 is a 35-year-old male presented with a history of hoarseness for 3 years with no risk factors. FOL showed a 1.2-cm polypoid growth on the right vocal cord. Total laryngectomy was performed and histopathology showed SpCC. Radiotherapy was given and the patient is alive without disease with regular follow-ups. Smoking and alcohol are thought to be the contributing factors causing this disease. Biphasic nature of the tumour requires pathological sampling for diagnostic confirmation. Surgery combined with radiotherapy has a better survival outcome. SpCC is a rare tumour with a tendency for locoregionalrecurrence. Surgery should remain the mainstay of treatment followed by post-operative radiotherapy for a better control.Key words: Larynx, radiotherapy, spindle cell carcinoma

Spindle Cell Carcinoma of Oral Cavity: A Rare Entity

2021 ◽  
Vol 20 (4) ◽  
pp. 923-925
Author(s):  
Ng CS ◽  
Mohd Razif M Y ◽  
Chew MX ◽  
Suria HMP
Keyword(s):  
Cell Carcinoma ◽  
Tooth Extraction ◽  
Spindle Cell ◽  
Histopathological Examination ◽  
Medical Science ◽  
Spindle Cell Carcinoma ◽  
Tumour Bulk ◽  
The Right ◽  
8Th Edition

Introduction:Spindle cell carcinomas (SpCC) are a rare variant of squamous cell carcinoma which is rarely encountered in the head and neck. It is also known as“pseudocarcinoma”, “sarcomatoidcarcinoma,” and “carcinosarcoma”.It has an aggressive nature and has poor prognosis despite aggressive treatment. Case report: A 48-year-old lady presented to us with a right painless upper gum swelling which was progressively enlarging for 3 months after tooth extraction. Examination of the oral a fungating mass over the right upper alveolus extending to the right upper gingivolabial sulcus. She was subjected to a debulking palliative to reduce the tumour bulk. The intraoperative samples sent for histopathological examination was reported as SpCC, AJCC (8th edition) stage pT2pN3b. She recovered well after the surgery with quality of life after the surgery. Bangladesh Journal of Medical Science Vol.20(4) 2021 p.923-925

Undifferentiated Sarcoma of the Parotid Gland With Osseous Metaplasia

2002 ◽  
Vol 126 (7) ◽  
pp. 849-852
Author(s):  
Sandra Wajstaub ◽  
Pratima Deb ◽  
Katherine A. Chorneyko
Keyword(s):  
Bone Formation ◽  
Parotid Gland ◽  
Unusual Case ◽  
Spindle Cell ◽  
Spindle Cell Carcinoma ◽  
Osseous Metaplasia ◽  
Diagnostic Challenge ◽  
Undifferentiated Sarcoma ◽  
Primary Sarcoma ◽  
The Right

Abstract Malignant spindle cell tumors of the parotid gland are a diagnostic challenge. We present an unusual case of such a tumor that occurred in the right parotid gland of a 53-year-old man. The clinical and histologic assessments were consistent with a primary sarcoma of the parotid gland. The tumor was composed of sheets of pleomorphic, spindle-shaped cells with an area of bone formation. By immunohistochemistry, the tumor cells were positive for vimentin and negative for epithelial markers. Electron microscopy revealed mesenchymal cells containing moderate amounts of rough endoplasmic reticulum. The major differential diagnostic considerations were spindle cell carcinoma, carcinosarcoma, and primary undifferentiated sarcoma with osseous metaplasia. The lack of epithelial features and the benign appearance of the bone formation led to a diagnosis of undifferentiated sarcoma of the parotid gland.

scholarly journals Surgical resection of a rapidly growing pulmonary spindle cell carcinoma by robot-assisted thoracoscopic surgery: a case report

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Akihiro Koen ◽  
Hideyuki Maeda ◽  
Yoji Nagashima ◽  
Masato Kanzaki
Keyword(s):  
Rheumatoid Arthritis ◽  
Cell Carcinoma ◽  
Surgical Resection ◽  
Spindle Cell ◽  
Thoracoscopic Surgery ◽  
Spindle Cell Carcinoma ◽  
Robot Assisted ◽  
Case Presentation ◽  
Abnormal Shadow ◽  
The Right

Abstract Background Pulmonary spindle cell carcinoma (PSCC) is an extremely rare tumor that is highly malignant and fast-growing. As chemotherapy and radiation therapy are ineffective, early surgical resection is effective for PSCC. Case presentation A 70-year-old woman with rheumatoid arthritis was referred to our hospital with an abnormal shadow. Chest computed tomography revealed a 33-mm-wide lobular mass in the right upper lobe. She was diagnosed with non-small cell lung cancer by bronchoscopic smear cytology. Although staging evaluation indicated stage IIIB (T3N2M0) disease, she required continued administration of immunosuppressants and prednisolone for rheumatoid arthritis. Therefore, robot-assisted thoracoscopic surgery (RATS) right upper lobectomy followed by lymph node dissection was performed without preoperative chemotherapy and radiotherapy. Pathological findings revealed PSCC. Conclusions We report a very rare case of pulmonary spindle cell carcinoma, successfully resected with RATS.

scholarly journals Combined pulmonary and thoracic wall resection for stage III lung cancer.

Thorax ◽  
1995 ◽  
Vol 50 (7) ◽  
pp. 782-784 ◽  
Author(s):  
S S Shah ◽  
P Goldstraw
Keyword(s):  
Lung Cancer ◽  
Stage Iii ◽  
Thoracic Wall ◽  
Thoracic Wall Resection

Evaluation of advanced lung cancer inflammation as potential prognostic markers in patients with colorectal cancer.

2017 ◽  
Vol 35 (15_suppl) ◽  
pp. e15142-e15142
Author(s):  
Julie Haewon Rowe ◽  
Fathima Kamil ◽  
Andre Yu ◽  
Curtis Jackson Wray ◽  
Putao Cen ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Logistic Regression ◽  
Survival Rates ◽  
Prognostic Index ◽  
Advanced Lung Cancer ◽  
Cancer Center ◽  
Logistic Regression Models ◽  
Colon Cancers ◽  
Cancer Inflammation ◽  
The Right

e15142 Background: The Advanced Lung cancer Inflammation (ALI) prognostic index evaluates the degree of systemic inflammation in cancer patients and has been validated in small cell lung and esophageal cancer. The “sidedness” of the colon primary has prognostic implications with left sided tumors having longer survival rates than right sided. Our hypothesis is that right sided colorectal cancers (CRC) will have a lower ALI. Methods: We conducted a retrospective review of newly diagnosed CRC patients who were seen and evaluated at a tertiary Cancer Center from 1/1/2005 to 12/31/2015. ALI is calculated as ALI = BMI x (serum albumin/NLR). NLR is the neutrophil to lymphocyte ratio. Logistic regression models were used to determine the association between primary colon cancer location and ALI. Results: A total of 279 patients were included in this study. 53% of patients were male and mean age was 63.4 years (SD 13.7). 52% of cancers were located on the right side. Using an ordered logistic regression, ALI was predictive of higher stage disease (p = 0.04). In those patients with stage III (n = 64) or IV (n = 136) disease, the likelihood of a low ALI was significantly higher for right-sided colon cancers (OR 2.12, 95%CI:1.18-7.76). Conclusions: The Advanced Lung Cancer Inflammation index appears to be related to both CRC stage and primary cancer location. Ongoing studies are needed to determine the relationship between ALI and CRC survival.

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