Conjunctival Stromal Tumor: Report of 2 New Cases and Review of the Literature

2020 ◽  
pp. 106689692094578
Author(s):  
Jonathan Lam ◽  
Andrea Ang ◽  
Tersia Vermeulen ◽  
Nima Mesbah Ardakani
Keyword(s):  
Surgical Excision ◽  
Stromal Tumor ◽  
Biological Behavior ◽  
Bulbar Conjunctiva ◽  
Age Group ◽  
Normal Pattern ◽  
Complete Surgical Excision ◽  
Tender Mass ◽  
Collagenous Stroma ◽  
Slow Growing

Conjunctival stromal tumor (COST) is an emerging entity with only a limited number of cases reported in the literature. In this report, we describe 2 additional cases, review the accumulative clinical and histopathological features and expand on the immunophenotypic property of this entity. COST appears to have a sporadic presentation, affecting both sexes and patients of variable ethnicity and age group and predominantly occurring on the bulbar conjunctiva as a slow-growing asymptomatic or slightly tender mass-like lesion. Histopathologically, COST is characterized by singly dispersed spindle to round cells, often with some degree of degenerative nuclear atypia, within a myxomatous to collagenous stroma. Lesional cells are characteristically positive for CD34 and vimentin, negative for S100, SOX10 and STAT6 and show a normal pattern of staining with RB1 by immunohistochemistry. The reported cases to date have shown an indolent biological behavior, reliably treated by a complete surgical excision.

scholarly journals A rare clinical case: schwannoma of tongue

2019 ◽  
Vol 5 (3) ◽  
pp. 789
Author(s):  
Chandra Veer Singh ◽  
Sheetal Radia ◽  
Saalim Sheikh ◽  
Vijay Haribhakti
Keyword(s):  
Head And Neck ◽  
Rare Case ◽  
Neck Region ◽  
Surgical Excision ◽  
Imaging Studies ◽  
Head And Neck Tumours ◽  
Head And Neck Region ◽  
Complete Surgical Excision ◽  
Slow Growing ◽  
Rule Out

<p class="abstract">Schwannoma are slow growing tumours, which can arise from any peripheral nerve. 10% of schwannomas that occur in the head and neck region mostly originate from the vagus or sympathetic nervous system. Extracranial schwannomas in the head and neck region are rare neoplasm. Intraoral schwannoma are only 1% of the all head and neck tumours. Diagnosis is established by imaging studies such as magnetic resonance imaging or computed tomography, while FNAC is used to rule out other conditions. We report a rare case of lingual schwannomas generally present as a painless lump schwannoma of the tongue in a 27-year-old male complaining of asymptomatic swelling over a posterolateral surface of the tongue, treated by complete surgical excision. The diagnosis was established on the basis of clinical, histopathological, and immunohistochemical examination. We report a rare case of schwannoma over the posterolateral surface of tongue. Prognosis is good for the patient when this condition is correctly diagnosed as the condition rarely recurs after complete resection.</p>

scholarly journals UCD with MCD-like inflammatory state: surgical excision is highly effective

2021 ◽  
Vol 5 (1) ◽  
pp. 122-128
Author(s):  
Miao-yan Zhang ◽  
Ming-nan Jia ◽  
Jia Chen ◽  
Jun Feng ◽  
Xin-xin Cao ◽  
...  
Keyword(s):  
Surgical Treatment ◽  
Treatment Options ◽  
Surgical Excision ◽  
Castleman Disease ◽  
High Response Rate ◽  
Biological Behavior ◽  
Multicentric Castleman Disease ◽  
Complete Surgical Excision ◽  
Inflammatory State

Abstract Unicentric Castleman disease (UCD) is a rare lymphoproliferative disorder presenting as a single nodal mass with characteristic histopathology. Patients with UCD are typically asymptomatic with normal laboratory markers, whereas patients with multicentric Castleman disease (MCD) demonstrate multicentric lymphadenopathy and cytokine storm–induced systemic inflammatory symptoms. This retrospective analysis of 116 UCD cases identified 19 (16.4%) cases with an MCD-like inflammatory state (UCD-MIS). We compared treatments and outcomes between cases of UCD-MIS and UCD–non-MIS to evaluate the role of surgery and illuminate biological behavior of UCD-MIS. There were differences in the distribution of histopathological subtypes (plasmacytic histopathology was more frequently seen, 52.6% vs 13.4%; P &lt; .001) between the 2 groups. However, both groups demonstrated good responses to surgical treatment, suggesting that UCD-MIS in some patients still shared common biological behavior with UCD in other patients. Sixteen (94.2%) patients with UCD-MIS underwent complete surgical excision alone, and the systemic inflammation resolved completely in all of them. This high response rate suggests surgical treatment as a potential cure for this unique subset of patients. After a median follow-up duration of 64 months (range, 2-239 months), neither lymphadenopathy nor the inflammatory state recurred. However, inflammation may progress in patients with irresectable disease, and treatment options other than surgery should be considered in these patients.

scholarly journals Novel surgical technique for management of tongue schwannoma: case report

2019 ◽  
Vol 5 (3) ◽  
pp. 804
Author(s):  
Neha Jain ◽  
Shama Shishodia ◽  
Ruchima Dham ◽  
Suparna Roy ◽  
Sachin Goel
Keyword(s):  
Case Report ◽  
Treatment Options ◽  
Neck Region ◽  
Surgical Excision ◽  
Uneventful Recovery ◽  
Common Site ◽  
Head And Neck Region ◽  
Complete Surgical Excision ◽  
Oral Approach ◽  
Slow Growing

<p class="abstract">Schwannomas are rare, solitary, slow growing, smooth surfaced and well encapsulated tumors. Schwannomas of head and neck region account for 25-40% of all the cases. Approximately 1%–12% of schwannomas occur intraorally, the tongue being the most common site. Complete surgical excision is the treatment of choice.  In this article, we describe a case of tongue schwannoma in a child, along with diagnostic and treatment options of tongue lesions. The tongue mass was completely excised via trans-oral approach using coblation method. The patient followed up for 1 year; he had an uneventful recovery and no recurrence.</p>

scholarly journals Solitary intrascrotal neurofibroma in a child: A case report

2021 ◽  
Vol 1 (2) ◽  
Author(s):  
Ghadir Jaber ◽  
Vipul Gupta ◽  
Usman Javaid ◽  
Diary Mohammed ◽  
Mamoun AlMarzouqi
Keyword(s):  
Histopathological Examination ◽  
Plexiform Neurofibroma ◽  
Surgical Excision ◽  
Age Group ◽  
Pediatric Age ◽  
Rare Entity ◽  
Tissue Mass ◽  
Pediatric Age Group ◽  
Complete Surgical Excision ◽  
Hypoechoic Mass

Background: Neurofibroma (NF) remains a rare entity among various scrotal masses in the pediatric age group. We report a case of solitary intrascrotal extra testicular plexiform neurofibroma in a 6-year-old child with the clinical management of this rare entity and review of the literature.   Case Summary: A 6-year-old male presented with incidentally noticed intrascrotal swelling. Clinical examination confirmed the presence of solitary intrascrotal swelling with normal testis. Radiological imaging showed the presence of a hypoechoic mass in the left hemiscrotum with normal both testes. Surgical exploration showed the presence of unencapsulated soft tissue mass and histopathological examination (HPE) confirmed the diagnosis of plexiform neurofibroma. Thorough evaluation ruled out features of neurofibromatosis 1 thus confirming the diagnosis of solitary intrascrotal extratesticular plexiform neurofibroma. Complete surgical excision resulted in satisfactory recovery with no recurrence on follow-up Conclusion: Neurofibroma although rare should be considered as a differential in the diagnosis of an intrascrotal mass in the pediatric age group. The benign nature of the lesion and extratesticular origin usually makes testis sparing surgical excision feasible which remains the treatment of choice with excellent prognosis and minimal chances of recurrence. A thorough histopathological examination is mandatory to rule out neurofibromatosis.

scholarly journals Cystic schwannoma of the pelvis

2013 ◽  
Vol 95 (1) ◽  
pp. e1-e2 ◽  
Author(s):  
T Jindal ◽  
S Mukherjee ◽  
MR Kamal ◽  
RK Sharma ◽  
N Ghosh ◽  
...  
Keyword(s):  
Schwann Cells ◽  
Bladder Outlet Obstruction ◽  
Outlet Obstruction ◽  
Surgical Excision ◽  
Nerve Fibres ◽  
Complete Surgical Excision ◽  
Benign Tumours ◽  
Slow Growing ◽  
Open Excision ◽  
Cystic Schwannoma

Schwannomas are benign tumours that arise from the Schwann cells of nerve fibres. They commonly occur in the head and neck, mediastinum and extremities. They are extremely rare in the pelvis. These are usually slow growing tumours and are often detected incidentally. Pre-operative diagnosis is extremely difficult as there are no definitive signs on imaging. Aspiration biopsy is often inconclusive or misleading. Surgical excision is both diagnostic and therapeutic. As these tumours are often large in size, open excision is most commonly performed. We describe a case of a large, cystic schwannoma of the pelvis causing bladder outlet obstruction and bilateral hydroureteronephrosis. Complete surgical excision was performed laparoscopically.

INTRAOSSEOUS ANGIOLIPOMA OF THE CRANIUM

Neurosurgery ◽  
2009 ◽  
Vol 64 (1) ◽  
pp. E189-E190 ◽  
Author(s):  
Kenny Yu ◽  
James Van Dellen ◽  
Philip Idaewor ◽  
Federico Roncaroli
Keyword(s):  
Clinical Presentation ◽  
Subcutaneous Tissue ◽  
Rare Condition ◽  
Surgical Excision ◽  
Benign Tumors ◽  
Complete Surgical Excision ◽  
History Of ◽  
Titanium Cranioplasty ◽  
Intraosseous Lesion ◽  
Slow Growing

Abstract OBJECTIVE We describe an intraosseous angiolipoma of the cranium and discuss the outcome. Angiolipomas are benign tumors that consist of mature adipose tissue and abnormal vessels. They occur predominantly in the subcutaneous tissue of the trunk and upper limbs. Only 4 examples of intraosseous angiolipomas have been reported in the literature, all of which involved the mandible and ribs. CLINICAL PRESENTATION A 39-year-old man presented with a right parietal swelling. The patient initially refused surgery; thus it was possible to follow this case for 11 years, allowing us to evaluate the natural history of this rare condition. INTERVENTION Complete surgical excision of the intraosseous lesion was achieved with a titanium cranioplasty performed at intervals. Fifteen months after surgery, no recurrence was seen. CONCLUSION This is the first known report of intraosseous angiolipoma of the cranium. Angiolipomas are rare, benign, slow-growing tumors with an excellent prognosis. On preoperative neuroimaging, they may mimic intraosseous angiomas, lipomas, or intraosseous meningiomas. Total resection is curative.

Complex Dysembryoplastic Neuroepithelial Tumor With Pilocytic Astrocytoma Component

2019 ◽  
Vol 152 (Supplement_1) ◽  
pp. S44-S45
Author(s):  
Sandhyarani Dasaraju ◽  
Krutika Patel ◽  
Shalla Akbar ◽  
Osama Elkadi
Keyword(s):  
Contrast Enhancement ◽  
Pilocytic Astrocytoma ◽  
Early Recognition ◽  
Complex Form ◽  
Surgical Excision ◽  
Biological Behavior ◽  
Glioneuronal Tumor ◽  
Dysembryoplastic Neuroepithelial Tumor ◽  
Who Grade ◽  
Complete Surgical Excision

Abstract Objectives Dysembryoplastic neuroepithelial tumor (DNET) is an uncommon mixed glioneuronal tumor. DNET is classified as WHO grade I neoplasm and commonly seen in the temporal lobe of children and young adults with features of pharmacoresistant seizures. The term complex DNET defines those tumors associated with additional features, including a pilocytic astrocytoma (PA) component, a finding that is rarely described in the literature. Methods Here we report a 16-year-old male who presented with seizures. On imaging, a 5.5 × 2.2 × 2.1-cm multiloculated mass was centered in the left frontoparietal gray matter with solid and cystic components and focal areas of contrast enhancement. Results Microscopic examination revealed a noninfiltrative glioneuronal neoplasm composed of a bland population of round to oval cells arranged around pools of mucinous material. Occasional large neuronal cells were noted. Focal areas composed of elongated astrocytic cells demonstrating piloid morphology were also present. No high-grade features were demonstrated. The findings are consistent with DNET, complex form in addition to a second component with piloid features resembling pilocytic astrocytoma. Conclusion The early recognition of DNET is important as it has an excellent prognosis on complete surgical excision without use of adjunct therapies. Unresected or incompletely removed DNET and secondary radiochemotherapy may give rise to recurrence and malignancy. The development of the secondary neoplasm challenges the stability in terms of biological behavior and highlights the importance of complete surgical excision and close follow-up. Our patient had neither undergone previous surgery nor received any adjuvant therapy, and hence this case is a de novo development of PA in a DNET. The association of contrast enhancement with DNET is an unusual finding in this case.

scholarly journals Nasal Cavity Schwannoma—A Case Report and Review of the Literature

2021 ◽  
pp. 014556132110345
Author(s):  
Jyun-Yi Liao ◽  
Herng-Sheng Lee ◽  
Bor-Hwang Kang
Keyword(s):  
Case Report ◽  
Nasal Cavity ◽  
Surgical Excision ◽  
Lateral Wall ◽  
Benign Tumors ◽  
Review Of The Literature ◽  
Recommended Treatment ◽  
Complete Surgical Excision ◽  
Slow Growing ◽  
Histology And Immunohistochemistry

Schwannomas are rare slow-growing benign tumors arising from Schwann cells lining the nerve sheaths. Head and neck schwannomas account for about one-third of all cases, and only 4% of them arise from the sinonasal tract. Its diagnosis is based on histology and immunohistochemistry. Complete surgical excision is the most recommended treatment option, and endoscopic surgery has been widely performed in recent years. In this study, we presented a case of a 55-year-old female with schwannoma arising from the lateral wall of the nasal cavity, causing epistaxis and rhinorrhea. The patient underwent endoscopic excision with prompt resolution of symptoms. The reported cases of nasal cavity schwannoma were reviewed and summarized for educational purposes.

Schwannoma of Oropharynx: A Rare Presentation

2013 ◽  
Vol 5 (2) ◽  
pp. 14-16
Author(s):  
Hemantkumar Onkar Nemade ◽  
Subbalaxmi Atmaram Jaiswal ◽  
Vidhyadhar Rudrappa Borade
Keyword(s):  
Neck Region ◽  
Cost Effective ◽  
Surgical Excision ◽  
Benign Tumors ◽  
Rare Presentation ◽  
Myelinated Nerve ◽  
Complete Excision ◽  
Head And Neck Region ◽  
Complete Surgical Excision ◽  
Slow Growing

ABSTRACT Schwannomas are slow growing, encapsulated, solitary, benign tumors. They can arise from any myelinated nerve as they are tumors of neural sheath Schwann cells. Schwannoma seen in head and neck region are most commonly found in tongue, floor of mouth but rarely in oropharynx and tonsils. They are usually asymptomatic and rarely undergo malignant transformation. Schwannomas are considered radioresistant and recure less frequently after complete excision. Hence, complete surgical excision is treatment of choice. We are presenting a case of elderly female with oropharyngeal schwannoma completely extirpated transorally by dissection method by cold instruments. Due to rarity of presentation the surgical approach to this lesion is not well established. Following surgery the raw area created was well epithelized and patient relieved symptoms without significant morbidity. We conclude that this is a cost-effective and simple approach for management of other similar cases in future.

Vagal Nerve Schwannoma: Presentation of Two Case Reports

2016 ◽  
Vol 8 (3) ◽  
pp. 116-118
Author(s):  
Atishkumar B Gujrathi ◽  
Vijayalaxmi Ambulgekar ◽  
Shrinivas Chavan
Keyword(s):  
Case Reports ◽  
Surgical Excision ◽  
Neck Mass ◽  
Vagal Nerve ◽  
Lateral Neck ◽  
Benign Lesions ◽  
Complete Surgical Excision ◽  
Lateral Neck Swelling ◽  
Slow Growing ◽  
Nose And Throat

ABSTRACT Vagal nerve schwannomas are rare neural sheath tumors. Although schwannomas are generally benign lesions, they are known to enlarge at a rate of 2.5 to 3 mm per year according to published reports. Vagal nerve schwannoma usually occurs between the 3rd and 5th decades of life, it does not show sex predilection, with both sexes being equally affected, and it most often presents as a painless, slow-growing, lateral neck mass. The treatment of choice is complete surgical excision with preservation of the neural pathway, when it is possible. These tumors, in fact, are almost always benign, and a conservative surgical approach is emphasized by most of the authors. Here, we are presenting two cases of cervical vagal schwannoma, both were middle aged females and presenting in the ear, nose, and throat (ENT) department as a painless lateral neck swelling and were operated by horizontal skin crease incision. Of the two cases, we succeeded to secure nerve functions in one case. The clinical features, diagnosis, management, and pathological findings of cervical vagal schwannoma are discussed. How to cite this article Gujrathi AB, Ambulgekar V, Chavan S. Vagal Nerve Schwannoma: Presentation of Two Case Reports. Int J Otorhinolaryngol Clin 2016;8(3):116-118.

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