Risk Assessment in Solitary Fibrous Tumor of the Uterine Corpus: Report of a Case and Systematic Review of the Literature

2021 ◽  
pp. 106689692110257
Author(s):  
Laura Ardighieri ◽  
Andrea Palicelli ◽  
Federico Ferrari ◽  
Monica Ragnoli ◽  
Iacopo Ghini ◽  
...  
Keyword(s):  
Systematic Review ◽  
Solitary Fibrous Tumor ◽  
Web Of Science ◽  
Female Genital Tract ◽  
Scoring Systems ◽  
Uterine Corpus ◽  
Fibrous Tumor ◽  
Female Genital

Solitary fibrous tumor (SFT) is an uncommon fibroblastic tumor occurring preferentially in the pleura, with a variable clinical course. SFT can arise also in numerous extrathoracic sites and very rarely in the female genital tract, with only scarce reports of uterine SFT. We reported a new uterine SFT arising in a 45-year-old woman, and we performed a systematic review of SFT cases of the uterine corpus interrogating the electronic databases PubMed, Web of Science, and Scopus. We identified only 13 patients diagnosed with SFT of the uterine corpus, including our one. Complete clinical workout at disease presentation showed no evidence of extrauterine spread in all cases, except for 1 patient who presented with metastatic disease. Tumor recurrences/metastases occurred in a minority of the patients and were poorly related to clinicopathological risk factors and patients stratification based on different scoring systems. Since the long-term clinical behavior of uterine SFT is limited and poorly predictable, extended follow-up is recommended also for all cases arising in the uterine corpus.

Recurrent Solitary Fibrous Tumor of the Pleura With Malignant Transformation

2004 ◽  
Vol 128 (4) ◽  
pp. 460-462
Author(s):  
Rani Kanthan ◽  
Bahman Torkian
Keyword(s):  
Malignant Transformation ◽  
Solitary Fibrous Tumor ◽  
Immunohistochemical Staining ◽  
White Woman ◽  
Accurate Diagnosis ◽  
Malignant Progression ◽  
Biological Behavior ◽  
Fibrous Tumor

Abstract Recurrent solitary fibrous tumor of the pleura with malignant progression occurs rarely. We report a case of solitary fibrous tumor of the pleura in an 85-year-old white woman that recurred 4 times during a span of 10 years and subsequently underwent malignant transformation. The accurate diagnosis of solitary fibrous tumor is aided by ancillary techniques, such as immunohistochemical staining; however, with malignant transformation, such tools may be of limited value. Long-term clinical follow-up is recommended for all patients with solitary fibrous tumor because of the potential adverse biological behavior of this tumor, which may lead to repeated recurrences and/or malignant transformation.

Late toxicity of brachytherapy after female genital tract tumors treated during childhood: Prospective evaluation with a long-term follow-up

2015 ◽  
Vol 117 (2) ◽  
pp. 206-212 ◽  
Author(s):  
Antonin Levy ◽  
Helene Martelli ◽  
Chiraz Fayech ◽  
Veronique Minard-Colin ◽  
Isabelle Dumas ◽  
...  
Keyword(s):  
Genital Tract ◽  
Female Genital Tract ◽  
Late Toxicity ◽  
Prospective Evaluation ◽  
Long Term Follow Up ◽  
Female Genital

Solitary Fibrous Tumor of the Female Genital Tract A Case Report and Review of the Literature

2007 ◽  
Vol 26 (3) ◽  
pp. 259-264 ◽  
Author(s):  
Olaf James Biedrzycki ◽  
Naveena Singh ◽  
Hani Habeeb ◽  
Neville Wathen ◽  
Asma Faruqi
Keyword(s):  
Case Report ◽  
Solitary Fibrous Tumor ◽  
Genital Tract ◽  
Female Genital Tract ◽  
Review Of The Literature ◽  
Fibrous Tumor ◽  
Female Genital

scholarly journals Malignant solitary fibrous tumor of the thyroid: a case-report and review of the literature

2014 ◽  
Vol 58 (4) ◽  
pp. 402-406 ◽  
Author(s):  
Wellington Alves Filho ◽  
Renata Regina da Graça Lorencetti Mahmoud ◽  
Daniel Marin Ramos ◽  
Vergilius José Furtado de Araujo-Filho ◽  
Patricia Picciarelli de Lima ◽  
...  
Keyword(s):  
Thyroid Gland ◽  
Solitary Fibrous Tumor ◽  
Spindle Cell ◽  
Spindle Cell Neoplasm ◽  
Cellular Atypia ◽  
Long Term Follow Up ◽  
History Of ◽  
Fibrous Tumor

Solitary fibrous tumor (SFT) is an uncommon spindle-cell neoplasm that most often involves the pleura, rarely occurring in extra-thoracic locations. Twenty-six cases of SFT arising in the thyroid gland have been described. We report a case of a 60-year-old woman presenting an 8-month history of enlargement of the neck associated with dysphagia. The patient underwent a right hemithyroidectomy and SFT of the thyroid was diagnosed. Immunohistochemistry showed positivity for CD34 marker, and the high number of mitoses and the presence of cellular atypia suggested that the tumor was malignant. To our knowledge, this is the second case of malignant SFT of the thyroid gland ever reported. Due to the rarity of these tumors, the indication of adjuvant therapy and prognosis are uncertain. Long-term follow-up after surgical resection seems to be advisable.

scholarly journals Factors for postoperative recurrence of orbital solitary fibrous tumor: an analysis of long‐term clinical follow‐up results from a Chinese tertiary hospital

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Peng Yang ◽  
Hao-Cheng Liu ◽  
E Qiu ◽  
Wei Wang ◽  
Jia-Liang Zhang ◽  
...  
Keyword(s):  
Recurrence Rate ◽  
Solitary Fibrous Tumor ◽  
Postoperative Recurrence ◽  
Surgical Approaches ◽  
Pathological Feature ◽  
Correct Operation ◽  
Incomplete Removal ◽  
Fibrous Tumor

Abstract Background This study analyzed the clinical features, imaging manifestations, histopathology, immunohistochemistry, and surgical approaches of the orbital solitary fibrous tumor (OSFT), as well as the factors for postoperative recurrence of such disease. Methods The clinical data of 16 patients with OSFT treated in our center from 2003 to 2020 were analyzed retrospectively, and the clinical symptoms, treatment methods, and follow-up results were recorded. Results Of the 16 patients, 8 were females (50.0 %) and 8 were males (50.0 %); the average age of treatment was 37 ± 7 years and the median follow-up time was 74 (8, 228) months. Sixteen patients with OSFT underwent a total of 29 operations, of which 12 were transorbital approach operations and 17 were transfronto-orbital approach operations. Ten patients (10/16, 62.5 %) had recurrence. The recurrence rate of transorbital approach operations was 83.3 % (10/12), and the recurrence rate of transfronto-orbital approach operations was 17.6 % (3/17). No patients had treatment-related complications. Conclusions The main pathological feature of OSFT is a benign tumor. OSFT has a tendency to grow toward the cranio-orbital junction. The postoperative recurrence rate of OSFT is relatively high, so complete tumor resection is very important for prognosis. Inappropriate surgical approaches can lead to incomplete removal of the tumor and cause recurrence. Choosing the correct operation approach according to the position of the OSFT in the orbit and complete removal of the dura mater and bone affected by the tumor is crucial for the prognosis. Nevertheless, regular long-term follow-up after complete resection is necessary.

scholarly journals Solitary Fibrous Tumor of the Pleura: Surgery and Clinical Course in 18 Cases

2009 ◽  
Vol 17 (4) ◽  
pp. 378-381 ◽  
Author(s):  
Alessandro Bini ◽  
Jury Brandolini ◽  
Fabio Davoli ◽  
Giampiero Dolci ◽  
Francesco Sellitri ◽  
...  
Keyword(s):  
Surgical Treatment ◽  
Solitary Fibrous Tumor ◽  
Clinical Course ◽  
Survival Rates ◽  
Pleural Mesothelioma ◽  
Perioperative Mortality ◽  
Solitary Fibrous Tumors ◽  
Fibrous Tumor

Solitary fibrous tumors of the pleura are very rare neoplasms that can sometimes present with malignant features. Between 1984 and 2007, 18 cases were treated in our institution. There were 7 men and 11 women, with a median age of 56 years (range, 33-77 years). All patients underwent surgical treatment. Except for one case with hemangiopericytic features, all tumors were histologically the fibrous type of pleural mesothelioma. Resections were radical and there were no recurrences. There was no perioperative mortality. The outcome was excellent, and all patients have been followed up continuously. Survival rates at 3, 5, and 10 years were calculated as 86.7%, 75%, and 66.7%. One patient died after 18 months (malignant type of solitary fibrous tumor), and 2 died of unrelated disease after 24 and 53 months. Surgery is the treatment of choice, and careful long-term clinical follow-up is required.

Pelvic Inflammatory Disease

2009 ◽  
Vol 2 (9) ◽  
pp. 517-521
Author(s):  
Alexander Hodson
Keyword(s):  
Pelvic Inflammatory Disease ◽  
Inflammatory Disease ◽  
Female Genital Tract ◽  
Reproductive Age ◽  
Common Condition ◽  
Women Of Reproductive Age ◽  
Infection And Inflammation ◽  
Female Genital

Pelvic inflammatory disease (PID), infection and inflammation of the upper female genital tract, is a common condition managed by General Practitioners (GPs). It accounts for one in 60 consultations in women of reproductive age. Early diagnosis, management and, if necessary, referral is essential to help prevent serious long-term complications such as ectopic pregnancy, infertility and chronic pelvic pain. This article outlines the causes, clinical features, treatment and follow-up of PID.

scholarly journals Solitary fibrous tumor of the scrotum: a case report and review of the literature

BMC Urology ◽  
2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Tsung-Hsin Chang ◽  
Marcelo Chen ◽  
Chih-Chiao Lee
Keyword(s):  
Solitary Fibrous Tumor ◽  
Soft Tissue Tumor ◽  
English Literature ◽  
Surgical Excision ◽  
Case Presentation ◽  
Long Term Follow Up ◽  
English Medical Literature ◽  
Fibrous Tumor

Abstract Background Solitary fibrous tumor (SFT) is a rare soft tissue tumor originally reported in the pleura. Although it has been reported in various extra-pleural sites, the occurrence of SFT in the scrotum is extremely rare. Herein, we present a 48-year-old man who had scrotal SFT. There are very few reported cases of genitourinary SFTs, this is only the fifth report of SFT of the scrotum in the English medical literature. Case presentation In this study, we report on a 48-year-old man who presented with a 5 × 8 cm scrotal mass between his testes. Physical examination revealed a 4.7 × 8.5 cm lobulated tumor mass located between his testicles. Surgical excision of the tumor with scrotal approach was done and pathology reported a SFT. The patient was alive without tumor recurrence or distant metastasis during ongoing follow-up for 9 months post-operatively.. Conclusion Scrotal SFTs are very rare and only five cases have been reported in English literature to date. Treatment often involves surgical resection, and a definite diagnosis is made with the help of immunohistochemistry. The current general consensus for the management of SFTs is long-term follow-up after surgical excision of the tumor.

scholarly journals Factors for Postoperative Recurrence of Orbital Solitary Fibrous Tumor: An Analysis of Long-Term Clinical Follow-Up Results From a Chinese Tertiary Hospital

2020 ◽  
Author(s):  
Peng Yang ◽  
Hao-Cheng Liu ◽  
E Qiu ◽  
Wei Wang ◽  
Jia-Liang Zhang ◽  
...  
Keyword(s):  
Recurrence Rate ◽  
Solitary Fibrous Tumor ◽  
Postoperative Recurrence ◽  
Surgical Approaches ◽  
Pathological Feature ◽  
Correct Operation ◽  
Incomplete Removal ◽  
Fibrous Tumor

Abstract BackgroundThis study analyzed the clinical features, imaging manifestations, histopathology, immunohistochemistry, and surgical approaches of the orbital solitary fibrous tumor (OSFT), as well as the factors for postoperative recurrence of such disease.MethodsThe clinical data of 16 patients with OSFT treated in our center from 2003 to 2020 were analyzed retrospectively, and the clinical symptoms, treatment methods, and follow-up results were recorded.ResultsOf the 16 patients, 8 were females (50.0%) and 8 were males (50.0%); the average age of treatment was 37 ± 7 years and the median follow-up time was 74 (8, 228) months. Sixteen patients with OSFT underwent a total of 29 operations, of which 12 were transorbital approach operations and 17 were transfronto-orbital approach operations. Ten patients (10/16, 62.5%) had recurrence. The recurrence rate of transorbital approach operations was 83.3% (10/12), and the recurrence rate of transfronto-orbital approach operations was 17.6% (3/17). No patients had treatment-related complications.ConclusionsThe main pathological feature of OSFT is a benign tumor. OSFT has a tendency to grow toward the cranio-orbital junction. The postoperative recurrence rate of OSFT is relatively high, so complete tumor resection is very important for prognosis. Inappropriate surgical approaches can lead to incomplete removal of the tumor and cause recurrence. Choosing the correct operation approach according to the position of the OSFT in the orbit and complete removal of the dura mater and bone affected by the tumor is crucial for the prognosis. Nevertheless, regular long-term follow-up after complete resection is necessary.

Sign in / Sign up

Export Citation Format

Share Document