scholarly journals Genetic and Environmental Risks for High Blood Pressure Among African American Mothers and Daughters

2009 ◽  
Vol 11 (1) ◽  
pp. 53-65 ◽  
Author(s):  
Jacquelyn Y. Taylor ◽  
Rosanna Maddox ◽  
Chun Yi Wu
Keyword(s):  
Physical Activity ◽  
Blood Pressure ◽  
African American ◽  
African American Women ◽  
Sodium Intake ◽  
Buccal Swab ◽  
African American Mothers ◽  
Cross Sectional ◽  
Mothers And Daughters ◽  
American Women

Objective: To determine the relationship between genetic and environmental lifestyle factors (physical activity and sodium) on blood pressure (BP) among African-American women. Method: In this cross-sectional study involving 108 African-American mothers and daughters from a Midwestern area, investigators obtained BP measurements, information on minutes of physical activity, amount of sodium intake, and buccal swab saliva samples. Results: Of the 4 single nucleotide polymorphisms (SNPs) on the sodium bicarbonate cotransporter gene (SLC4A5), rs8179526 had a statistically significant interaction with cytosine/thymine (C/T) genotype by sodium status on systolic BP (SBP; p = .0077). For gene × physical activity interaction, 2 significant interactions (cytosine/adenine [C/A] genotype by physical activity and adenine/adenine [A/A] genotype by physical activity, p = .0107 and p = .0171, respectively) on SBP and 1 on diastolic BP (DBP; A/A genotype by physical activity, p = .0233) were found on rs1017783. Two significant guanine/adenine [G/A] genotype by physical activity interactions were found on rs6731545 for SBP and DBP (p = .0160 and p = .0492, respectively). Discussion: A gene × environmental interaction with rs8179526 has a protective effect on SBP in African-American women with high sodium intake. Participants with C/T genotype of rs8179526 who consumed greater than 2,300 mg of sodium had lower SBP than those who consumed less than recommended. Women with thymine/thymine (T/T) genotype of rs8179526 who consumed greater than 2,300 mg had lower SBP than those who consumed less. Awareness of both the protective and deleterious properties of rs8179526 in African-American women may one day assist in determining appropriate treatment plans.

Physical Activity Reduces Blood Pressure Load Indices in African- American Women

2004 ◽  
Vol 36 (Supplement) ◽  
pp. S95
Author(s):  
Beth A. Staffileno ◽  
Steven M. Hollenberg ◽  
Lola Coke ◽  
Ann Minnick
Keyword(s):  
Physical Activity ◽  
Blood Pressure ◽  
African American ◽  
African American Women ◽  
American Women ◽  
Pressure Load ◽  
Blood Pressure Load ◽  
Load Indices

Physical Activity Reduces Blood Pressure Load Indices in African- American Women

2004 ◽  
Vol 36 (Supplement) ◽  
pp. S95
Author(s):  
Beth A. Staffileno ◽  
Steven M. Hollenberg ◽  
Lola Coke ◽  
Ann Minnick
Keyword(s):  
Physical Activity ◽  
Blood Pressure ◽  
African American ◽  
African American Women ◽  
American Women ◽  
Pressure Load ◽  
Blood Pressure Load ◽  
Load Indices

Increasing physical activity with African–American women using Facebook™ and Pedometers

2021 ◽  
Author(s):  
Donna J. Biederman ◽  
Valerie K. Sabol ◽  
Julie Thompson ◽  
Quiana Duncan ◽  
Katherine C. Pereira
Keyword(s):  
Physical Activity ◽  
African American ◽  
African American Women ◽  
American Women

scholarly journals Community Engagement in the Development of an mHealth-Enabled Physical Activity and Cardiovascular Health Intervention (Step It Up): Pilot Focus Group Study (Preprint)

2018 ◽  
Author(s):  
Joniqua Nashae Ceasar ◽  
Sophie Elizabeth Claudel ◽  
Marcus R Andrews ◽  
Kosuke Tamura ◽  
Valerie Mitchell ◽  
...  
Keyword(s):  
Physical Activity ◽  
African American ◽  
African American Women ◽  
Participatory Research ◽  
Community Based Participatory Research ◽  
Minority Population ◽  
Washington Dc ◽  
Community Based ◽  
Convenience Sample ◽  
American Women

BACKGROUND Community-based participatory research is an effective tool for improving health outcomes in minority communities. Few community-based participatory research studies have evaluated methods of optimizing smartphone apps for health technology-enabled interventions in African Americans. OBJECTIVE This study aimed to utilize focus groups (FGs) for gathering qualitative data to inform the development of an app that promotes physical activity (PA) among African American women in Washington, DC. METHODS We recruited a convenience sample of African American women (N=16, age range 51-74 years) from regions of Washington, DC metropolitan area with the highest burden of cardiovascular disease. Participants used an app created by the research team, which provided motivational messages through app push notifications and educational content to promote PA. Subsequently, participants engaged in semistructured FG interviews led by moderators who asked open-ended questions about participants’ experiences of using the app. FGs were audiorecorded and transcribed verbatim, with subsequent behavioral theory-driven thematic analysis. Key themes based on the Health Belief Model and emerging themes were identified from the transcripts. Three independent reviewers iteratively coded the transcripts until consensus was reached. Then, the final codebook was approved by a qualitative research expert. RESULTS In this study, 10 main themes emerged. Participants emphasized the need to improve the app by optimizing automation, increasing relatability (eg, photos that reflect target demographic), increasing educational material (eg, health information), and connecting with community resources (eg, cooking classes and exercise groups). CONCLUSIONS Involving target users in the development of a culturally sensitive PA app is an essential step for creating an app that has a higher likelihood of acceptance and use in a technology-enabled intervention. This may decrease health disparities in cardiovascular diseases by more effectively increasing PA in a minority population.

Sign in / Sign up

Export Citation Format

Share Document