scholarly journals Multimodal imaging of a vascularized idiopathic epiretinal membrane

2020 ◽  
pp. 112067212098252
Author(s):  
Rodrigo Anguita ◽  
Hagar Khalid ◽  
Cristina Arpa ◽  
Janice Roth ◽  
Bishwanath Pal ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Retinal Detachment ◽  
Fluorescein Angiography ◽  
Epiretinal Membrane ◽  
Multimodal Imaging ◽  
Fundus Photography ◽  
Vascular Endothelial ◽  
Optical Coherence ◽  
Idiopathic Epiretinal Membrane ◽  
Endothelial Growth Factor

Purpose: To report a case of vascularized idiopathic epiretinal membrane including the multimodal imaging. Methods: Findings on clinical examination, color fundus photography, spectral-domain optical coherence tomography, optical coherence tomography angiography, and fluorescein angiography. Results: Sixty-three-year-old woman with a previous rhegmatogenous retinal detachment (RRD) who presented with an asymptomatic idiopathic neovascular complex below an epiretinal membrane. It was assessed with fluorescein angiography, OCT and OCT-A. The vascularized ERM was already present previously to the retinal detachment. Conclusion: Our case report describes an example of idiopathic epiretinal membrane complicated by neovascularization; we hypothesized hypertension could be one of the factors in this case, as it may lead to decreased retinal perfusion and upregulation in vascular endothelial growth factor (VEGF). Multimodal imaging can help in detecting neovascularized ERM.

Evolution of Idiopathic Epiretinal Membrane Studied by Optical Coherence Tomography

2008 ◽  
Vol 18 (6) ◽  
pp. 980-988 ◽  
Author(s):  
P.G. Theodossiadis ◽  
V.G. Grigoropoulos ◽  
T. Kyriaki ◽  
J. Emfietzoglou ◽  
J. Vergados ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Epiretinal Membrane ◽  
Optical Coherence ◽  
Idiopathic Epiretinal Membrane

Natural History of Idiopathic Epiretinal Membrane in Eyes with Good Vision Assessed by Spectral-Domain Optical Coherence Tomography

2015 ◽  
Vol 234 (2) ◽  
pp. 91-100 ◽  
Author(s):  
Ik Soo Byon ◽  
Gang Yun Pak ◽  
Han Jo Kwon ◽  
Kyong Ho Kim ◽  
Sung Who Park ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Visual Acuity ◽  
Natural History ◽  
Visual Function ◽  
Epiretinal Membrane ◽  
Membrane Separation ◽  
Early Stage ◽  
Optical Coherence ◽  
Idiopathic Epiretinal Membrane ◽  
History Of

Purpose: To investigate the natural history of idiopathic epiretinal membrane (ERM) in eyes with good visual function using optical coherence tomography (OCT). Methods: Sixty-two eyes of 58 patients with idiopathic ERM, visual acuity of 20/40 or better, and no significant metamorphopsia were included. The best corrected visual acuity (BCVA), central macular thickness (CMT), membrane configuration, and ellipsoid zone signal data over 24 months were retrospectively analyzed. Based on OCT findings, ERM configurations were categorized as global attachment (GA), partial attachment (PA), pseudohole, and vitreomacular traction (VMT). Results: The mean BCVA and CMT did not change significantly between baseline and 24 months. GA, PA, pseudohole, and VMT types were observed in 33, 19, 9, and 1 eye at baseline, and in 20, 22, 10, and 1 eye at 24 months, respectively. A membrane configuration change was noted in 24 eyes (38.7%) during follow-up, and the distribution shifted from GA to the other types (p < 0.001). Six eyes had visual loss due to membrane progression, and 4 eyes had spontaneous membrane separation. Of the 10 eyes with progression or separation, 6 were of the PA type. Conclusions: Although the BCVA remains stable over 2 years in most idiopathic ERM eyes with good visual function at baseline, the membrane configuration may change, affecting visual acuity. The GA type would be an early stage, and the PA type is prone to changes in visual acuity.

scholarly journals Early Retinal Flow Changes after Vitreoretinal Surgery in Idiopathic Epiretinal Membrane Using Swept Source Optical Coherence Tomography Angiography

2019 ◽  
Vol 8 (12) ◽  
pp. 2067 ◽  
Author(s):  
Rodolfo Mastropasqua ◽  
Rossella D’Aloisio ◽  
Pasquale Viggiano ◽  
Enrico Borrelli ◽  
Carla Iafigliola ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Epiretinal Membrane ◽  
Optical Coherence Tomography Angiography ◽  
Optical Coherence ◽  
Vascular Changes ◽  
Ilm Peeling ◽  
Swept Source ◽  
Idiopathic Epiretinal Membrane ◽  
Capillary Plexus ◽  
Superficial Capillary Plexus

(1) Background: The aim of this observational cross-sectional work was to investigate early retinal vascular changes in patients undergoing idiopathic epiretinal membrane (iERM) surgery using swept source optical coherence tomography angiography (SS-OCTA); (2) Methods: 24 eyes of 24 patients who underwent vitrectomy with internal limiting membrane (ILM) peeling were evaluated pre- and postoperatively using SS-OCTA system (PLEX Elite 9000, Carl Zeiss Meditec Inc., Dublin, CA, USA). For each eye, five 6x6-mm OCTA volume scans were acquired by two observers independently. The en face images of superficial capillary plexus (SCP) were then exported to imageJ and a semi-automated algorithm was used for subsequent quantitative analysis. Perfusion density (PD), vessel length density (VLD), vessel diameter index (VDI) and vessel tortuosity (VT) of SCP were evaluated in both the parafoveal (2.5 mm diameter) and perifoveal areas (5.5 mm diameter); (3) Results: At OCTA analysis statistically significant differences were found between controls and diseased eyes for all parameters in parafoveal and perifoveal regions (p < 0.001; p < 0.05) except for perifoveal VLD. During 6-month follow up, both anatomical/perfusion and functional parameters showed a statistically significant improvement if compared to preoperative values. In detail, at one-month post vitrectomy, VLD and VT significantly changed in parafoveal region (p = 0.043; p = 0.045), while PD and VDI showed a trend of increase in both parafoveal and perifoveal region. At 6 months after surgery, PD, VLD and VT of parafoveal region significantly improved (p = 0.021, p = 0.018, p = 0.047 respectively). (4) Conclusions: SS-OCTA provides a quantitative and qualitative analysis of the superficial capillary plexus allowing for early vascular changes assessment after vitrectomy with iERM and ILM peeling.

scholarly journals Optical Coherence Tomography Angiography of Retinal Arterial Macroaneurysm before and after Treatment

2018 ◽  
Vol 2018 ◽  
pp. 1-4
Author(s):  
Victoria S. Chang ◽  
Stephen G. Schwartz ◽  
Harry W. Flynn
Keyword(s):  
Optical Coherence Tomography ◽  
Fluorescein Angiography ◽  
Multimodal Imaging ◽  
Optical Coherence Tomography Angiography ◽  
Intravitreal Bevacizumab ◽  
Optical Coherence ◽  
Flow Signal ◽  
Retinal Arterial Macroaneurysm ◽  
Diagnosis And Management ◽  
Before And After

A case of retinal arterial macroaneurysm (RAM) is presented with multimodal imaging, including commercially available optical coherence tomography angiography (OCT-A). Following treatment with intravitreal bevacizumab, reduction of flow signal through the RAM is documented. OCT-A provides useful information for the diagnosis and management of at least some patients with RAM, without the need for traditional fluorescein angiography.

Optical Coherence Tomography Angiography of Polypoidal Neovascularization Associated with Choroidal Nevus

2016 ◽  
Vol 27 (1) ◽  
pp. 9-12 ◽  
Author(s):  
Maria Vittoria Cicinelli ◽  
Lorenzo Iuliano ◽  
Alessandro Rabiolo ◽  
Alessandro Marchese ◽  
Giuseppe Querques ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Optical Coherence Tomography Angiography ◽  
Vascular Endothelial ◽  
Optical Coherence ◽  
Spectral Domain Oct ◽  
En Face Oct ◽  
En Face ◽  
Choroidal Nevus ◽  
Endothelial Growth Factor ◽  
Different Levels

Purpose To report a case of juxtapapillary polypoidal choroidal neovascularization (PCNV) associated with choroidal nevus investigated by means of optical coherence tomography angiography (OCT-A). Methods Case report. Results A 72-year-old woman presented with visual loss and metamorphopsia in her left eye for 5 days secondary to PCNV that developed on the border of a juxtapapillary choroidal nevus. Fluorescein angiography, indocyanine green angiography, and spectral-domain OCT confirmed the diagnosis. En face OCT-A disclosed a large tangled hyperreflective PCNV spreading from the optic disc at different levels of the choriocapillaris; the polyp lumina appeared hyporeflective. The patient was treated with 3 intravitreal injections of anti-vascular endothelial growth factor with partial functional recovery. Conclusions Our case showed the application of OCT-A in the diagnosis of a case of active PCNV complicating a benign intraocular tumor.

scholarly journals Multimodal Imaging in AIDS-Related Ocular Cryptococcosis

2021 ◽  
Vol 2021 ◽  
pp. 1-7
Author(s):  
Maria Fernanda Flores Herrera ◽  
Nicolas Dauby ◽  
Evelyne Maillart ◽  
Agnes Libois ◽  
Alberto Papaleo ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Indocyanine Green ◽  
Multimodal Imaging ◽  
Critical Role ◽  
Fundus Photography ◽  
Optical Coherence ◽  
Ocular Manifestations ◽  
Baseline Evaluation ◽  
Almost All

Purpose. To report multimodal imaging findings in two cases of AIDS-related cryptococcal chorioretinitis associated with uveitis and vasculitis. Methods. Findings on clinical examination, color fundus photography, fluorescein and indocyanine green angiographies, and optical coherence tomography. Patients. Both patients were diagnosed with Cryptococcus neoformans meningitis in the setting of untreated HIV infection with CD4+ T cell count < 100 / m m 3 . Ocular manifestations occurred during the course of the antifungal therapy for meningitis. Results. In both cases, fundus showed vitritis. Fluorescein angiography allowed the characterization of vasculitis lesions, and indocyanine green angiography indicated choroidal involvement. In combination with optical coherence tomography, ICG and FA allowed the assessment of treatment response. Conclusion. These two cases reveal the potential of C. neoformans to infect almost all ocular structures and the critical role of multimodal imaging in baseline evaluation and in the follow-up of patients.

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