Pediatric pilomyxoid astrocytoma – ophthalmic and neuroradiologic manifestations

2021 ◽  
pp. 112067212110556
Author(s):  
Joyce N Mbekeani ◽  
Maaly Abdel Fattah ◽  
Anwar Ul Haq ◽  
Essam Al Shail ◽  
Manzoor Ahmed

Pilomyxoid astrocytoma (PMA) is an atypical subtype of pilocytic astrocytoma (PA), which presents in children and young adults. The incidence of PMA is low, so there is no standardized treatment protocol for it. Here, we present a 62-year-old woman with recurrent PMA, which is important for the understanding and treatment of the disease.


2017 ◽  
Vol 39 (4) ◽  
pp. e219-e223 ◽  
Author(s):  
Ryan D. Metts ◽  
Walter Bartynski ◽  
Cynthia T. Welsh ◽  
Stephen Kinsman ◽  
Amy-Lee Bredlau

2007 ◽  
Vol 17 (4) ◽  
pp. 371-374 ◽  
Author(s):  
Mishal Mendiratta-Lala ◽  
Shehanaz Kader Ellika ◽  
Jorge A. Gutierrez ◽  
Suresh C. Patel ◽  
Rajan Jain

2019 ◽  
Vol 10 ◽  
pp. 235
Author(s):  
Alireza Tabibkhooei ◽  
Alireza Sadeghipour ◽  
Arash Fattahi

Background: Pilomyxoid astrocytoma (PMA) is a variant of pilocytic astrocytomas but exhibits more aggressive behavior. Further, it is more prevalent in the hypothalamic/chiasmatic regions and is only rarely encountered in the thoracic spine. Case Description: A 9-year-old male presented with severe spastic paraparesis (motor/sensory) attributed to a thoracic cord PMA and scoliosis. The magnetic resonance (MR) showed an intraaxial ill-defined expansile lesion with heterogeneous enhancement extending from the cervicothoracic junction to conus medullaris. A multilevel decompressive laminectomy was performed with restricted tumor debulking; an expansile duraplasty was also effected. Two years later, the patient has moderately improved and has not shown any symptom progression. Conclusion: We recommend the early performance of a thoracic MR in children with idiopathic scoliosis presenting with the onset of a significant spastic paraparesis.


2015 ◽  
Vol 5 ◽  
pp. 41
Author(s):  
Sanghyeon Kim ◽  
Myongjin Kang ◽  
Sunseob Choi ◽  
Dae Cheol Kim

Pilomyxoid astrocytoma (PMA) is a rare central nervous system tumor that has been included in the 2007 World Health Organization Classification of Tumors of the Central Nervous System. Due to its more aggressive behavior, PMA is classified as Grade II neoplasm by the World Health Organization. PMA predominantly affects the hypothalamic/chiasmatic region and occurs in children (mean age of occurrence = 10 months). We report a case of a 24-year-old man who presented with headache, nausea, and vomiting. Brain CT and MRI revealed a mass occupying only the third ventricle. We performed partial resection. Histological findings, including monophasic growth with a myxoid background, and absence of Rosenthal fibers or eosinophilic granular bodies, as well as the strong positivity for glial fibrillary acidic protein were consistent with PMA.


2008 ◽  
Vol 30 (9) ◽  
pp. 945-951 ◽  
Author(s):  
Ricardo J. Komotar ◽  
Brad E. Zacharia ◽  
Michael E. Sughrue ◽  
J. Mocco ◽  
Benjamin S. Carson ◽  
...  

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