Corrigendum

2015 ◽  
Vol 19 (6) ◽  
pp. 604-604
Keyword(s):  
Primary Prevention ◽  
Skin Cancer ◽  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Actinic Keratoses ◽  
Non Melanoma Skin Cancer ◽  
Cancer Guidelines ◽  
Melanoma Skin

Guenther LC, Barber K, Searles GE, Lynde CW, Janiszewski P, Ashkenas J, for the Canadian Non-melanoma Skin Cancer Guidelines Committee. Non-melanoma Skin Cancer in Canada Chapter 1: Introduction to the Guidelines. J Cutan Med Surg. 2015;19(3):205-215. Original DOI: 10.1177/1203475415588652 Barber K, Searles GE, Vender R, Teoh H, Ashkenas J, for the Canadian Non-melanoma Skin Cancer Guidelines Committee. Non-melanoma Skin Cancer in Canada Chapter 2: Primary Prevention of Non-melanoma Skin Cancer. J Cutan Med Surg. 2015;19(3):216-226. Original DOI: 10.1177/1203475415576465 Poulin Y, Lynde CW, Barber K, Vender R, Claveau J, Bourcier M, Ashkenas J, for the Canadian non-Melanoma Skin Cancer Guidelines Committee. Non-melanoma Skin Cancer in Canada Chapter 3: Management of Actinic Keratoses. J Cutan Med Surg. 2015;19(3):227-238. Original DOI: 10.1177/1203475415583414 Zloty D, Guenther LC, Sapijaszko M, Barber K, Claveau J, Adamek T, Ashkenas J, for the Canadian Non-melanoma Skin Cancer Guidelines Committee. Non-melanoma Skin Cancer in Canada Chapter 4: Management of Basal Cell Carcinoma. J Cutan Med Surg. 2015;19(3):239-248. Original DOI: 10.1177/1203475415586664 Sapijaszko M, Zloty D, Bourcier M, Poulin Y, Janiszewski P, Ashkenas J, for the Canadian Non-melanoma Skin Cancer Guidelines Committee. J Cutan Med Surg. 2015;19(3):249-259. Original DOI: 10.1177/1203475415582318 In the above articles, the following disclaimer from the Canadian Dermatology Association should have been included: The Canadian Dermatology Association (CDA) recognizes the scientific merit of these guidelines. The CDA did not participate in their development or provide content.

Trends in Non-Melanoma Skin Cancer (Basal Cell Carcinoma and Squamous Cell Carcinoma) in Canada

2015 ◽  
Vol 20 (2) ◽  
pp. 166-175 ◽  
Author(s):  
Mariam Abbas ◽  
Sunil Kalia
Keyword(s):  
Squamous Cell Carcinoma ◽  
Skin Cancer ◽  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Basal Cell ◽  
Age Cohorts ◽  
Non Melanoma Skin Cancer ◽  
Younger Age ◽  
Melanoma Skin

Background: Despite its increased incidence and status as the most prevalent cancer in Canada, there is a paucity of epidemiological data on non-melanoma skin cancer (NMSC). Objective: To assess trends of keratinocyte carcinomas (KC) in Canada over 5 decades. Methods: Articles published from 1960 to 2015 on NMSC in Canada were identified through MEDLINE. Six articles met our search criteria. Results: Overall, KC has increased. However, the rate of increase in the past decade has slowed down and decreased in younger age cohorts. Men had higher incidences of KC. In both sexes, the basal cell carcinoma and squamous cell carcinoma ratio was ≥2.5:1. Keratinocyte carcinomas were most commonly located on the head and neck, and increasing rates are occurring on the trunk. Limitations: The methods of registering skin cancer cases vary among different provinces. Conclusion: Keratinocyte carcinomas incidence is overall increasing; however, there may be evidence that the incidence is leveling off and decreasing in younger age cohorts.

scholarly journals Basal cell carcinoma masquerading as lupus vulgaris - A case report

2021 ◽  
Vol 7 (2) ◽  
pp. 172-174
Author(s):  
Geo Danny C ◽  
Abhinesh N ◽  
Shreya Srinivasan ◽  
Avinash Pravin
Keyword(s):  
Case Report ◽  
Skin Cancer ◽  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Lupus Vulgaris ◽  
Non Melanoma Skin Cancer ◽  
The World ◽  
Melanoma Skin

Basal cell carcinoma is the most commonly occurring non melanoma skin cancer in the world and overall incidence is still increasing. Metastases is rare in Basal cell carcinoma. Herein we present a case report of Basal cell carcinoma mimicking Lupus vulgaris

scholarly journals Perianal Basal Cell Carcinoma

2015 ◽  
Vol 7 (1) ◽  
pp. 25-28 ◽  
Author(s):  
Isil Bulur ◽  
Emine Boyuk ◽  
Zeynep Nurhan Saracoglu ◽  
Deniz Arik
Keyword(s):  
Risk Factors ◽  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
The Body ◽  
Additional Risk ◽  
Closed Area ◽  
Non Melanoma Skin Cancer ◽  
The Face ◽  
Melanoma Skin

Basal cell carcinoma (BCC) is the most common non-melanoma skin cancer. Exposure to ultraviolet light is an important risk factor for BCC development and the disorder therefore develops commonly on body areas that are more exposed to sunlight, such as the face and neck. It is uncommon in the closed area of the body and quite rare in the perianal and genital regions. Herein, we report a 34-year-old patient with perianal BCC who had no additional risk factors.

scholarly journals Study on Clinical, Histopathological Features and Evaluation Results of Skin Cancer Treatment in Can Tho Oncology Hospital

2016 ◽  
Vol 10 (3) ◽  
pp. 104
Author(s):  
Nguyen Van Qui ◽  
Phan Nguyen Ngoc
Keyword(s):  
Skin Cancer ◽  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Skin Flap ◽  
The Elderly ◽  
Developed Countries ◽  
Wide Resection ◽  
Histopathological Features ◽  
Non Melanoma Skin Cancer

Skin cancer as the most common cancer diagnosis tend to be increasing. This condition is a particularly significant issue in developed countries. This study aimed to describe the clinical features, histopathological features, complications, and early surgical treatment outcomes of skin cancer in CanTho Oncology Hospital from 2014 to 2015. This descriptive prospective study involved all patients with non-melanoma skin cancer that were examined and treated at Can Tho Oncology Hospital from July 2014 to March 2015. There were 78 cases selected. Skin cancer was found to be more common among older patients. The prevalence of basal cell carcinoma was found higher than squamous cell carcinoma with percentage worth 76.9% and 23.1% respectively. Worth 73.1% of all the patients in the study underwent surgery with wide resection and reconstruction. In this study, most patients were the elderly. The basal cell carcinoma was the most common. The main treatment was surgery with wide resection and reconstruction. The complication was rare 1.3% with skin flap necrosis Penelitian pada Fitur Klinis, Histopatologis dan Hasil Evaluasi PengobatanKanker di Rumah Sakit Onkologi Can ThoKanker kulit, diagnosis kanker paling umum, cenderung mengalami peningkatan. Kondisi ini secara khusus merupakan isu penting di negara-negara maju. Penelitian ini bertujuan untuk mendeskripsikan fitur klinis, fitur hispatologis, komplikasi dan hasil pengobatan bedah awal kanker kulit di Rumah Sakit Onkologi Can Tho dari tahun 2014 sampai 2015. Penelitian deskriptif prospektif ini melibatkan seluruh pasien dengan kanker kulit nonmelanoma yang diuji dan diobati di Rumah Sakit Onkologi Can Tho dari Juli 2014 sampai Maret 2015. Terdapat 78 kasus terpilih. Kanker kulit ditemukan lebih umum pada pasien yang lebih tua. Prevalensi karsinoma sel basal ditemukan lebih tinggi dibandingkan karsinoma sel skuamosa dengan persentase masing-masing 76,9% dan 23,1%. Sebesar 73,1% dari seluruh pasien dalam penelitian ini menjalani bedah dengan rekonstruksi dan reseksi yang lebar. Dalam penelitian ini, sebagian besar pasien adalah lanjut usia. Karsinoma sel basal adalah yang paling umum. Pengobatan utama adalah bedah dengan rekonstruksi dan reseksi yang lebar. Komplikasi jarang terjadi 1,3% dengan nekrosis lipatan kulit.

Somatic Mutations in TP53 Gene in Colombian Patients With Non-melanoma Skin Cancer

2022 ◽  
Vol 2 (1) ◽  
pp. 107-114
Author(s):  
LUZ DARY GUTIÉRREZ-CASTAÑEDA ◽  
JOHN NOVA ◽  
MARÍA IRENE CEREZO-CORTÉS
Keyword(s):  
Skin Cancer ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Basal Cell ◽  
Somatic Mutations ◽  
Tp53 Gene ◽  
Non Melanoma Skin Cancer ◽  
Basal Cell Carcinomas ◽  
Frequent Mutations ◽  
Melanoma Skin

Background/Aim: Non-melanoma skin cancer is the most common cancer in the world. Somatic mutations in the TP53 gene are associated with the development of this cancer. To describe mutations in exons 5-8 of the TP53 gene in a sample of Colombian patients with non-melanoma skin cancer. Materials and Methods: One hundred and fifteen patients with non-melanoma skin cancer were included. Exons 5-8 were amplified and analyzed by PCR-High Resolution Melting and Sanger sequencing. Results: Fifty-seven patients with basal cell carcinomas and 58 with squamous cell carcinomas were studied. 16% of patients with basal cell carcinoma and 26% of patients with squamous cell carcinoma had mutations in the TP53 gene. The most frequent mutations were substitutions, while three patients had deletions. The most frequent mutation was p.R158G. Conclusion: The analysis showed that Colombian individuals with non-melanoma skin cancer have genetic TP53 variants different from those reported as recurrent for this disease.

scholarly journals In vitro Antiproliferative Effects of Cotinus coggygria Scop. on human non-melanoma and melanoma skin cancer cells

2021 ◽  
Vol 9 (7) ◽  
Author(s):  
Georgi Antov ◽  
Georgi Antov
Keyword(s):  
Squamous Cell Carcinoma ◽  
Side Effects ◽  
Skin Cancer ◽  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Basal Cell ◽  
Aqueous Fraction ◽  
Cotinus Coggygria ◽  
Melanoma Skin

Skin cancer is one of the most frequently diagnosed malignancies worldwide and its incidence constantly increases. The disease divides in two major subtypes: non-melanoma and melanoma skin cancer. The main drawbacks of the traditional skin cancer therapy are primary and acquired drug resistance and serious side effects due to the nonspecific treatments targeting. Despite advances in therapy strategies there is a need of new affordable natural anti-skin cancer agents, which to possess higher efficiency without causing detrimental side effects. Medicinal plants provide great possibility for the discovery of new anticancer therapeutics with preventive and treatment potential. Cotinus coggygria Scop. is a plant species widely applied in phytotherapy predominantly against disorders of the skin and mucosal tissues. The herb has a large range of valuable biological activities but its anticancer properties have not been thoroughly studied. The aim of the present research was to assess the antiproliferative properties of the crude leaf aqueous ethanolic extract from Bulgarian herb C. coggygria and its chloroformic and aqueous fractions on a panel of human skin cancer cell lines: basal cell carcinoma (TE 354.T), squamous cell carcinoma (A431) and malignant melanoma (A375) and to compare them to the cell growth inhibitory potential on normal dermal cell line (BJ). The antiproliferative capacity of the plant substances was investigated using MTT assay and microscopy cell morphology observation after 72 h cell treatment in a wide scale of concentrations. The obtained results showed that the crude extract and both fractions inhibit significant proliferation of A431 squamous cell carcinoma and A375 melanoma cells with the highest cytostatic effect registered for the aqueous fraction on A375 cells with a half maximal inhibitory concentration value of 44.33 ?g/ml. C. coggygria exhibited no cytostatic activity towards TE 354.T basal cell carcinoma cells. The established marked slight

scholarly journals Early Onset Basal Cell Carcinoma: Surgical Approach

2014 ◽  
Vol 41 (1) ◽  
pp. 82-87
Author(s):  
M. Betekhtin ◽  
J. Ananiev ◽  
G. Tchernev ◽  
L. Zisova ◽  
S. Philipov ◽  
...  
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Early Onset ◽  
Surgical Excision ◽  
Nasolabial Fold ◽  
Non Melanoma Skin Cancer ◽  
Suitable Treatment ◽  
Excellent Cosmetic Result ◽  
Melanoma Skin

Summary Basal cell carcinoma (BCC) is the most frequent non-melanoma skin cancer. Only 5-15% of BCC cases can be found in patients aged 20-40 years (so-called early onset). The early onset BCC is characterized by active and aggressive tumour growth, clinically presenting in most of the cases as a morpheaform, locally infiltrating or recurrent BCC. Despite the advances in the study of the pathogenesis of this tumour, surgery remains the most used, most effective and most suitable treatment modality. We describe a case of a 39-year-old woman who developed an early onset BCC of the nasolabial fold. After the subsequent surgical excision an excellent cosmetic result was achieved.

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