A case of relapsing–remitting tumour-like inflammation of the central nervous system

2015 ◽  
Vol 21 (13) ◽  
pp. 1742-1745 ◽  
Author(s):  
Silvia Miante ◽  
Paola Perini ◽  
Francesca Rinaldi ◽  
Paolo Gallo
Keyword(s):  
Magnetic Resonance Imaging ◽  
Multiple Sclerosis ◽  
Central Nervous System ◽  
Nervous System ◽  
Magnetic Resonance ◽  
Inflammatory Disease ◽  
Resonance Imaging ◽  
Relapsing Remitting ◽  
The Central Nervous System

The case of a 37-year-old woman suffering from a relapsing–remitting tumefactive inflammatory disease of the central nervous system (CNS) is described. The patient had four severe relapses over eight years, and was treated with steroids, immunosuppression and plasma-exchange with modest benefit. No magnetic resonance imaging or cerebrospinal spinal fluid findings suggestive of multiple sclerosis emerged during the eight-year follow-up. ‘Relapsing–remitting tumefactive inflammation’ seems to have the features of a distinct inflammatory CNS disease.

scholarly journals Current Concepts in the Neuropathology and Pathogenesis of Multiple Sclerosis

2010 ◽  
Vol 37 (S2) ◽  
pp. S5-S15 ◽  
Author(s):  
G.R. Wayne Moore
Keyword(s):  
Magnetic Resonance Imaging ◽  
Multiple Sclerosis ◽  
Central Nervous System ◽  
Nervous System ◽  
Magnetic Resonance ◽  
Demyelinating Disease ◽  
Resonance Imaging ◽  
Pathogenetic Mechanisms ◽  
The Central Nervous System ◽  
Shed Light

ABSTRACT:Multiple sclerosis (MS) has been classically regarded as an inflammatory demyelinating disease of the central nervous system. In recent years, the classification and pathogenesis of the disease have become controversial, particularly with respect to whether an individual patient demonstrates a single or multiple pathogenetic mechanisms in the establishment of the focal plaque of MS. It is also becoming increasingly apparent that there is a significant neurodegenerative component in the disease, involving not only plaques but the non-plaque parenchyma as well. Magnetic resonance imaging, together with histopathologic studies, will continue to shed light on the pathogenesis of these focal and diffuse abnormalities in MS.

scholarly journals False-positive magnetic resonance imaging findings in follow-up of pediatric patients with tumors of the central nervous system

2016 ◽  
Vol 4 ◽  
pp. 2050313X1666623 ◽  
Author(s):  
Satiro Nakamura De Oliveira ◽  
Ignacio Gonzalez-Gomez ◽  
Ashok Panigrahy ◽  
Mark Krieger ◽  
Gordon McComb ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Central Nervous System ◽  
Nervous System ◽  
Magnetic Resonance ◽  
False Positive ◽  
Pediatric Patients ◽  
Imaging Findings ◽  
Resonance Imaging ◽  
The Central Nervous System

HISTOPATHOLOGY OF MULTIPLE SCLEROSIS LESIONS DETECTED BY MAGNETIC RESONANCE IMAGING IN UNFIXED POSTMORTEM CENTRAL NERVOUS SYSTEM TISSUE

Brain ◽  
1991 ◽  
Vol 114 (2) ◽  
pp. 1013-1023 ◽  
Author(s):  
J. NEWCOMBE ◽  
C. P. HAWKINS ◽  
C. L. HENDERSON ◽  
H. A. PATEL ◽  
M. N. WOODROOFE ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Multiple Sclerosis ◽  
Central Nervous System ◽  
Nervous System ◽  
Magnetic Resonance ◽  
Resonance Imaging ◽  
Central Nervous System Tissue
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