scholarly journals Using the (Region of Interest ROI) Option of Magnetic Resonance Imaging (MRI) to Distinguish between Multiple Sclerosis (MS) and Ischemic Plaques in the Central Nervous System (CNS)

2017 ◽  
Vol 6 (12) ◽  
pp. 440-446
2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Carlos Pérez-Serrano ◽  
Álvaro Bartolomé ◽  
Núria Bargalló ◽  
Carmen Sebastià ◽  
Alfons Nadal ◽  
...  

AbstractCentral nervous system (CNS) abnormalities cause approximately 32–37.7% of terminations of pregnancy (TOP). Autopsy is currently the gold standard for assessing dead foetuses and stillborn. However, it has limitations and is sometimes subject to parental rejection. Recent studies have described post-mortem foetal magnetic resonance imaging (MRI) as an alternative and even complementary to autopsy for CNS assessment. Radiologists now play a key role in the evaluation of perinatal deaths. Assessment of foetal CNS abnormalities is difficult, and interpretation of foetal studies requires familiarisation with normal and abnormal findings in post-mortem MRI studies as well as the strengths and limitations of the imaging studies. The purpose of this pictorial review is to report our experience in the post-mortem MRI evaluation of the CNS system, including a description of the protocol used, normal CNS findings related to post-mortem status, abnormal CNS findings in our sample, and the correlation of these findings with histopathological results.


Author(s):  
Massimo Filippi ◽  
Maria A. Rocca

The classic view of multiple sclerosis (MS) as a chronic, inflammatory-demyelinating condition affecting solely the white matter (WM) of the central nervous system (CNS) has been challenged by the demonstration, from pathologic and magnetic resonance imaging (MRI) studies, of an extensive and diffuse involvement of the gray matter (GM). This observation has driven the application of modern MR technology and methods of analysis to quantify the extent and distribution of damage to the different compartments of the CNS, with the ultimate goal of improving our understanding of the factors associated with the accumulation of clinical disability and cognitive impairment in these patients.


Author(s):  
G.R. Wayne Moore

ABSTRACT:Multiple sclerosis (MS) has been classically regarded as an inflammatory demyelinating disease of the central nervous system. In recent years, the classification and pathogenesis of the disease have become controversial, particularly with respect to whether an individual patient demonstrates a single or multiple pathogenetic mechanisms in the establishment of the focal plaque of MS. It is also becoming increasingly apparent that there is a significant neurodegenerative component in the disease, involving not only plaques but the non-plaque parenchyma as well. Magnetic resonance imaging, together with histopathologic studies, will continue to shed light on the pathogenesis of these focal and diffuse abnormalities in MS.


2021 ◽  
Vol 37 (2) ◽  
Author(s):  
Jakub Majchrzycki ◽  
Agnieszka Permoda-Pachuta ◽  
Martyna Wachowiak

Objectives. Broad neuroimaging studies currently play an important role in the understanding of the principles of the functioning of the central nervous system (CNS). This applies not only to the healthy nervous system, but also to many pathological processes responsible for neurological and psychiatric disease entities. Magnetic resonance imaging (MRI) as a diagnostic imaging method has been used in medicine since the 1970s. Currently, the diagnosis of mental disorders and the choice of treatment methods are based primarily on the patient’s history, a structured interview and ancillary psychological tests. However, there is still a lack of more objective methods that can solve many diagnostic problems. Literature review. The aim of this paper is to present the methods of diagnosis by means of magnetic resonance imaging, helpful in many aspects of work with a patient diagnosed with a mental disorder. The paper reviews the literature on specific MRI techniques, such as volumetry, proton magnetic resonance spectroscopy, diffusion-weighted MR (DMR), fMRI (functional magnetic resonance imaging), MRI with magnetisation transfer coefficient, and tractography, which may open up new possibilities, also for psychiatry. Because of the large number of papers in this field, the focus was on three psychiatric disorders, i.e. schizophrenia and unipolar and bipolar affective disorder. Conclusions. It seems likely that in future magnetic resonance imaging of the central nervous system may make it possible not only to differentiate between mental disorders or to forecast their course, but also to determine the effectiveness of treatment of mental disorders and to predict possible side effects of the applied pharmacotherapy or electrotherapy.


2021 ◽  
Author(s):  
gordon heller

Abstract Morning Glory Anomaly is rare but its fundoscopic findings are well documented in the ophthalmologic literature. It is sporadic, without sexual predisposition and usually unilateral. Furthermore, it is associated with numerous central nervous system anomalies, including vasculopathy of the central nervous system. This case series reports four pediatric patients over a three year period in which ophthalmologic evaluation identified Morning Glory Anomaly. Magnetic Resonance Imaging (MRI) and Magnetic Resonance Angiography (MRA) were subsequently obtained to assess for associated intracranial vascular anomalies. This report is of significance as it demonstrates the spectrum of intracranial vasculopathy in this rare entity.


2020 ◽  
Vol 2 (1) ◽  
Author(s):  
Hai chao FU

Susceptibility weighted imaging (SWI) is a relatively new magnetic resonance imaging (MRI) technique that uses the difference in tissue magnetic susceptibility to image, and has unique value compared to traditional magnetic resonance imaging. This article summarizes its application in the central nervous system and provides a reference for imaging diagnosis and clinical treatment.


2015 ◽  
Vol 21 (13) ◽  
pp. 1742-1745 ◽  
Author(s):  
Silvia Miante ◽  
Paola Perini ◽  
Francesca Rinaldi ◽  
Paolo Gallo

The case of a 37-year-old woman suffering from a relapsing–remitting tumefactive inflammatory disease of the central nervous system (CNS) is described. The patient had four severe relapses over eight years, and was treated with steroids, immunosuppression and plasma-exchange with modest benefit. No magnetic resonance imaging or cerebrospinal spinal fluid findings suggestive of multiple sclerosis emerged during the eight-year follow-up. ‘Relapsing–remitting tumefactive inflammation’ seems to have the features of a distinct inflammatory CNS disease.


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