scholarly journals The presence of co-morbid mental health problems in a cohort of adolescents with chronic fatigue syndrome

2017 ◽  
Vol 23 (3) ◽  
pp. 398-408 ◽  
Author(s):  
Maria Elizabeth Loades ◽  
Katharine A Rimes ◽  
Sheila Ali ◽  
Kate Lievesley ◽  
Trudie Chalder
Keyword(s):  
Mental Health ◽  
Anxiety Disorder ◽  
Chronic Fatigue Syndrome ◽  
Trait Anxiety ◽  
Chronic Fatigue ◽  
The State ◽  
Self Report ◽  
Psychiatric Interview ◽  
Depression Diagnosis ◽  
Fatigue Syndrome

Objective: To report on the prevalence of mental health disorders in adolescents with chronic fatigue syndrome (CFS) and to compare the diagnoses identified by a brief clinician-administered psychiatric interview with self-report screening questionnaires. Design: Cross-sectional study. Setting: Consecutive attenders to specialist CFS clinics in the United Kingdom. Patients: N = 52 adolescents, age 12–18 years with CFS. Measures: Self-report questionnaires and a brief structured psychiatric diagnostic interview, administered by a researcher. Results: On the psychiatric interview, 34.6% met a diagnosis of major depressive disorder and 28.8% had an anxiety disorder. Of these, 15% had co-morbid anxiety and depression. Those with a depression diagnosis reported significantly greater interference on the school and social adjustment scale. They also scored significantly higher on trait anxiety, but not on state anxiety. There were no differences between those who had an anxiety disorder and those who did not on fatigue, disability or depressive symptoms. Children’s Depression Inventory (CDI) score was associated with a depression diagnosis on the psychiatric interview. However, neither the state nor the trait subscale of the State-Trait Anxiety Inventory (STAI) was associated with an anxiety diagnosis. Conclusion: Clinicians should assess for the presence of anxiety and depressive disorders in adolescents with CFS using a validated psychiatric interview. Treatment should be flexible enough to accommodate fatigue, depression and anxiety. Transdiagnostic approaches may suit this purpose. Goals should include pleasurable activities particularly for those who are depressed.

Physicians' Diagnoses of Psychiatric Disorders for People with Chronic Fatigue Syndrome

2002 ◽  
Vol 32 (2) ◽  
pp. 109-124 ◽  
Author(s):  
Susan R. Torres-Harding ◽  
Leonard A. Jason ◽  
Victoria Cane ◽  
Adam Carrico ◽  
Renee R. Taylor
Keyword(s):  
Chronic Fatigue Syndrome ◽  
Psychiatric Disorder ◽  
Psychiatric Disorders ◽  
Psychiatric Illness ◽  
Chronic Fatigue ◽  
Self Report ◽  
Control Group ◽  
Psychiatric Diagnoses ◽  
Psychiatric Interview ◽  
Fatigue Syndrome

Objective: To examine rates of psychiatric diagnoses given by patients' primary or regular physicians to persons with chronic fatigue syndrome (CFS), persons with psychiatrically explained fatigue, and a control group. Physicians' psychiatric diagnosis and participants' self-reported psychiatric diagnoses were compared to lifetime psychiatric diagnoses as measured by a structured psychiatric interview. Method: Participants were recruited as part of a community-based epidemiology study of chronic fatigue syndrome. Medical records of 23 persons with chronic fatigue syndrome, 25 persons with psychiatrically explained chronic fatigue, and 19 persons without chronic fatigue (controls) were examined to determine whether their physician had given a diagnosis of mood, anxiety, somatoform, or psychotic disorder. Lifetime psychiatric status was measured using the Structured Clinical Interview for the DSM-IV (SCID). Participants' self reports of specific psychiatric disorders were assessed as part of a detailed medical questionnaire. Results: Physicians' diagnosis of a psychiatric illness when at least one psychiatric disorder was present ranged from 40 percent in the psychiatrically explained group, 50 percent in the control group, and 64.3 percent in the CFS group. Participants in the psychiatrically explained group were more accurate than physicians in reporting the presence of a psychiatric disorder, and in accurately reporting the presence of a mood or anxiety disorder. Conclusions: The present investigation found underrecognition of psychiatric illness by physicians, with relatively little misdiagnosis of psychiatric illness. Physicians had particular difficulty assessing psychiatric disorder in those patients whose chronic fatigue was fully explained by a psychiatric disorder. Results emphasized the importance of using participant self report as a screening for psychiatric disorder.

scholarly journals How common are depression and anxiety in adolescents with chronic fatigue syndrome (CFS) and how should we screen for these mental health co-morbidities? A clinical cohort study

2020 ◽  
Author(s):  
Maria E. Loades ◽  
Rebecca Read ◽  
Lucie Smith ◽  
Nina T. Higson-Sweeney ◽  
Amanda Laffan ◽  
...  
Keyword(s):  
Mental Health ◽  
Anxiety Disorder ◽  
Chronic Fatigue Syndrome ◽  
Depression Scale ◽  
Chronic Fatigue ◽  
Anxiety And Depression ◽  
Fatigue Syndrome ◽  
Children’S Anxiety ◽  
Clinically Significant ◽  
Anxiety Depression

Abstract Adolescents with Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME) appear to be more likely to experience anxiety and/or depression using Patient Reported Outcome Measures (PROMs). However, we do not know how accurate these are at detecting problems in this patient group given the primary symptom of fatigue. We aimed to accurately determine the prevalence of anxiety/depression using gold-standard diagnostic interviews and evaluate the accuracy of PROMs measuring mood disorders in this patient group. We conducted a cross-sectional epidemiological study in a specialist tertiary paediatric CFS/ME service, England. The participants were164 12–18-year olds with clinician confirmed CFS/ME and their parents. The measures were a semi-structured diagnostic interview, the Kiddie Schedule for Affective Disorders and Schizophrenia, K-SADS, and questionnaires (Revised Children’s Anxiety and Depression Scale, RCADS; Spence Children’s Anxiety Scale, SCAS; Hospital Anxiety and Depression Scale, HADS). Parents completed the RCADS-P. 35% met the criteria for at least one common mental health problem. 20% had major depressive disorder, and 27% an anxiety disorder, with social anxiety and generalised anxiety being the most common. There was high co-morbidity, with 61% of those who were depressed also having at least one anxiety disorder. The questionnaires were moderately accurate (AUC > 0.7) at detecting clinically significant anxiety/depression, although only the RCADS-anxiety reached the predefined 0.8 sensitivity, 0.7 specificity target. Mental health problems are particularly common amongst adolescents with CFS/ME. Most screening tools were not sufficiently accurate in detecting clinically significant anxiety and depression, so these should be used with care in combination with thorough psychological/psychiatric assessment.

scholarly journals Screening instruments for psychiatric morbidity in chronic fatigue syndrome

1998 ◽  
Vol 91 (7) ◽  
pp. 365-368 ◽  
Author(s):  
Richard K Morriss ◽  
Alison J Wearden
Keyword(s):  
Mental Health ◽  
Chronic Fatigue Syndrome ◽  
Chronic Fatigue ◽  
Screening Instrument ◽  
Anxiety And Depression ◽  
Operating Characteristics ◽  
Psychiatric Interview ◽  
Mental Health Scale ◽  
Fatigue Syndrome ◽  
Gold Standards

Physicians require a screening instrument to detect psychiatric disorders in patients with chronic fatigue syndrome (CFS). Different threshold scores on the Hospital Anxiety and Depression scale (HAD) and the mental health scale of the Medical Outcome Survey (MOS) were compared with two gold standards for the presence or absence of psychiatric disorder, standard diagnostic criteria (DSM-III-R) and a threshold score for the number of psychiatric symptoms at a standardized psychiatric interview (Revised Clinical Interview Schedule total cut-off score of 11/12). They were compared by use of validating coefficients and receiver operating characteristics in 136 consecutive CFS medical outpatients. The HAD scale at cut-off of 9/10 was a valid and efficient screening instrument for anxiety and depression by comparison with both gold standards. The MOS mental health scale at its recommended cut-off score of 67/68 yielded too many false-positives to be recommended as a psychiatric screening instrument in CFS patients.

scholarly journals Structural brain changes versus self-report: machine-learning classification of chronic fatigue syndrome patients

2018 ◽  
Vol 236 (8) ◽  
pp. 2245-2253 ◽  
Author(s):  
Landrew S. Sevel ◽  
Jeff Boissoneault ◽  
Janelle E. Letzen ◽  
Michael E. Robinson ◽  
Roland Staud
Keyword(s):  
Machine Learning ◽  
Chronic Fatigue Syndrome ◽  
Chronic Fatigue ◽  
Self Report ◽  
Machine Learning Classification ◽  
Fatigue Syndrome ◽  
Brain Changes ◽  
Structural Brain

scholarly journals Effect of psychiatric disorders on outcome of cognitive-behavioural therapy for chronic fatigue syndrome

2005 ◽  
Vol 187 (2) ◽  
pp. 184-185 ◽  
Author(s):  
Judith Prins ◽  
Gijs Bleijenberg ◽  
Eufride Klein Rouweler ◽  
Jos Van Der Meer
Keyword(s):  
Chronic Fatigue Syndrome ◽  
Psychiatric Disorders ◽  
Cognitive Behavioural Therapy ◽  
Chronic Fatigue ◽  
Behavioural Therapy ◽  
Psychiatric Diagnoses ◽  
Psychiatric Interview ◽  
Fatigue Syndrome ◽  
Cognitive Behavioural ◽  
The Impact

SummaryPsychiatric disorders have been associated with poor outcome in individuals with chronic fatigue syndrome (CFS). This study examines the impact of psychiatric disorders on outcome of cognitive-behavioural therapy (CBT). Psychiatric diagnoses were assessed with a structured psychiatric interview in a CBT trial of 270 people with CFS. Lifetime and current psychiatric disorders were found in 50 and 32% respectively. No significant differences in fatigue severity and functional impairment following treatment were found between participants with and without psychiatric diagnoses.

scholarly journals Mental Health and Chronic Fatigue Syndrome: Is Mental Health the Culprit Behind Your Fatigue?

BioMedica ◽  
2020 ◽  
Vol 36 (2) ◽  
pp. 183-187
Author(s):  
Tahira Raza ◽  
Muhammad Ashraf Chaudhry ◽  
Ahsan Masu ◽  
Massiha Gulzar Ahmed ◽  
Minahil Ahmed ◽  
...  
Keyword(s):  
Mental Health ◽  
Chronic Fatigue Syndrome ◽  
Chronic Fatigue ◽  
Fatigue Syndrome

Chronic Fatigue Syndrome: All in the Mind? An Occupational Therapy Perspective

2000 ◽  
Vol 63 (4) ◽  
pp. 163-170 ◽  
Author(s):  
Lucy Moore
Keyword(s):  
Mental Health ◽  
Chronic Fatigue Syndrome ◽  
Occupational Therapy ◽  
Occupational Therapists ◽  
Chronic Fatigue ◽  
Structured Interview ◽  
Further Education ◽  
Fatigue Syndrome ◽  
Significant Difference ◽  
Mental Health Settings

This study aimed to establish the attitudes of occupational therapists towards chronic fatigue syndrome. Previously, no study had investigated the attitudes of health professionals towards this condition, which may be a factor in maintaining the uncertainty surrounding chronic fatigue syndrome. Twenty occupational therapists practising in either physical or mental health settings were recruited to this study. In order to achieve a depth of knowledge not gained by previous studies, the data were collected through a combination of quantitative and qualitative methodology by using a structured questionnaire and a semi-structured interview; the findings were analysed statistically and thematically. At variance with the literature, the results revealed a neutral to positive attitude towards chronic fatigue syndrome, with no significant difference in responses from participants practising in physical or mental health settings. A unique and valuable role was clearly identified for the profession of occupational therapy within the wider multidisciplinary framework. However, as 16 (80%) of the participants had met individuals with chronic fatigue syndrome, the lack of knowledge and need for further education and training were highlighted. Continuing professional development is fundamental in order to provide appropriate, sensitive and holistic services in the future for all individuals with chronic fatigue syndrome.

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