Machine Learning for Predicting Motor Improvement After Acute Subcortical Infarction Using Baseline Whole Brain Volumes

2021 ◽  
pp. 154596832110541
Author(s):  
Gang Liu ◽  
Jiewei Wu ◽  
Chao Dang ◽  
Shuangquan Tan ◽  
Kangqiang Peng ◽  
...  
Keyword(s):  
Machine Learning ◽  
Clinical Data ◽  
Machine Learning Techniques ◽  
Whole Brain ◽  
Brain Volumes ◽  
Poor Recovery ◽  
Learning Scheme ◽  
Learning Techniques ◽  
Motor Improvement ◽  
Subcortical Infarction

Background. Neuroimaging biomarkers are valuable predictors of motor improvement after stroke, but there is a gap between published evidence and clinical usage. Objective. In this work, we aimed to investigate whether machine learning techniques, when applied to a combination of baseline whole brain volumes and clinical data, can accurately predict individual motor outcome after stroke. Methods. Upper extremity Fugl-Meyer Assessments (FMA-UE) were conducted 1 week and 12 weeks, and structural MRI was performed 1 week, after onset in 56 patients with subcortical infarction. Proportional recovery model residuals were employed to assign patients to proportional and poor recovery groups (34 vs 22). A sophisticated machine learning scheme, consisting of conditional infomax feature extraction, synthetic minority over-sampling technique for nominal and continuous, and bagging classification, was employed to predict motor outcomes, with the input features being a combination of baseline whole brain volumes and clinical data (FMA-UE scores). Results. The proposed machine learning scheme yielded an overall balanced accuracy of 87.71% in predicting proportional vs poor recovery outcomes, a sensitivity of 93.77% in correctly identifying poor recovery outcomes, and a ROC AUC of 89.74%. Compared with only using clinical data, adding whole brain volumes can significantly improve the classification performance, especially in terms of the overall balanced accuracy (from 80.88% to 87.71%) and the sensitivity (from 92.23% to 93.77%). Conclusions. Experimental results suggest that a combination of baseline whole brain volumes and clinical data, when equipped with appropriate machine learning techniques, may provide valuable information for personalized rehabilitation planning after subcortical infarction.

Machine Learning Techniques for Corneal Diseases Diagnosis: A Survey

2020 ◽  
pp. 2150016
Author(s):  
Samer Kais Jameel ◽  
Sezgin Aydin ◽  
Nebras H. Ghaeb
Keyword(s):  
Machine Learning ◽  
Decision Making ◽  
Clinical Data ◽  
Medical Images ◽  
Diagnostic Techniques ◽  
Machine Learning Techniques ◽  
Corneal Disease ◽  
Automated Learning ◽  
Learning Techniques ◽  
The Way

Machine learning techniques become more related to medical researches by using medical images as a dataset. It is categorized and analyzed for ultimate effectiveness in diagnosis or decision-making for diseases. Machine learning techniques have been exploited in numerous researches related to corneal diseases, contribution to ophthalmologists for diagnosing the diseases and comprehending the way automated learning techniques act. Nevertheless, confusion still exists in the type of data used, whether it is images, data extracted from images or clinical data, the course reliant on the type of device for obtaining them. In this study, the researches that used machine learning were reviewed and classified in terms of the kind of utilized machine for capturing data, along with the latest updates in sophisticated approaches for corneal disease diagnostic techniques.

scholarly journals Application of Machine Learning Techniques to High-Dimensional Clinical Data to Forecast Postoperative Complications

PLoS ONE ◽  
2016 ◽  
Vol 11 (5) ◽  
pp. e0155705 ◽  
Author(s):  
Paul Thottakkara ◽  
Tezcan Ozrazgat-Baslanti ◽  
Bradley B. Hupf ◽  
Parisa Rashidi ◽  
Panos Pardalos ◽  
...  
Keyword(s):  
Machine Learning ◽  
Postoperative Complications ◽  
Clinical Data ◽  
Machine Learning Techniques ◽  
High Dimensional ◽  
Learning Techniques

Machine Learning for Clinical Data Processing

2011 ◽  
pp. 193-215
Author(s):  
Guo-Zheng Li
Keyword(s):  
Machine Learning ◽  
Data Processing ◽  
Clinical Data ◽  
Machine Learning Techniques ◽  
Support Vector ◽  
Data Sets ◽  
The Novel ◽  
Real World Data ◽  
Data Set ◽  
Learning Techniques

This chapter introduces great challenges and the novel machine learning techniques employed in clinical data processing. It argues that the novel machine learning techniques including support vector machines, ensemble learning, feature selection, feature reuse by using multi-task learning, and multi-label learning provide potentially more substantive solutions for decision support and clinical data analysis. The authors demonstrate the generalization performance of the novel machine learning techniques on real world data sets including one data set of brain glioma, one data set of coronary heart disease in Chinese Medicine and some tumor data sets of microarray. More and more machine learning techniques will be developed to improve analysis precision of clinical data sets.

Machine Learning for Clinical Data Processing

2012 ◽  
pp. 875-897
Author(s):  
Guo-Zheng Li
Keyword(s):  
Machine Learning ◽  
Data Processing ◽  
Clinical Data ◽  
Machine Learning Techniques ◽  
Support Vector ◽  
Data Sets ◽  
The Novel ◽  
Real World Data ◽  
Data Set ◽  
Learning Techniques

This chapter introduces great challenges and the novel machine learning techniques employed in clinical data processing. It argues that the novel machine learning techniques including support vector machines, ensemble learning, feature selection, feature reuse by using multi-task learning, and multi-label learning provide potentially more substantive solutions for decision support and clinical data analysis. The authors demonstrate the generalization performance of the novel machine learning techniques on real world data sets including one data set of brain glioma, one data set of coronary heart disease in Chinese Medicine and some tumor data sets of microarray. More and more machine learning techniques will be developed to improve analysis precision of clinical data sets.

Using machine learning techniques to reduce data annotation time

2006 ◽  
Author(s):  
Christopher Schreiner ◽  
Kari Torkkola ◽  
Mike Gardner ◽  
Keshu Zhang
Keyword(s):  
Machine Learning ◽  
Machine Learning Techniques ◽  
Data Annotation ◽  
Learning Techniques

Using Machine Learning Algorithms on Prediction of Stock Price

2020 ◽  
Vol 12 (2) ◽  
pp. 84-99
Author(s):  
Li-Pang Chen
Keyword(s):  
Machine Learning ◽  
Stock Price ◽  
Short Term Memory ◽  
Machine Learning Algorithms ◽  
Machine Learning Techniques ◽  
Support Vector ◽  
Short Term ◽  
Learning Techniques ◽  
Historical Database ◽  
Long Short Term Memory

In this paper, we investigate analysis and prediction of the time-dependent data. We focus our attention on four different stocks are selected from Yahoo Finance historical database. To build up models and predict the future stock price, we consider three different machine learning techniques including Long Short-Term Memory (LSTM), Convolutional Neural Networks (CNN) and Support Vector Regression (SVR). By treating close price, open price, daily low, daily high, adjusted close price, and volume of trades as predictors in machine learning methods, it can be shown that the prediction accuracy is improved.

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