scholarly journals The Effect of Different Metabolic Syndrome

2016 ◽  
Vol 11 (1) ◽  
pp. 158-163 ◽  
Author(s):  
Orhan Ünal Zorba ◽  
Hakkı Uzun ◽  
Görkem Akça ◽  
Selim Yazar

Because various criteria are used to define metabolic syndrome (MetS), this study examines the most relevant definition for patients with benign prostatic enlargement (BPE). Most studies regarding the link between MetS and BPE/lower urinary tract symptoms (LUTS) have used the National Cholesterol Education Program Adult Treatment Panel III criteria for diagnosis, while a few have used criteria from the International Diabetes Federation and/or American Heart Association. Patients with LUTS due to BPE are classified as having MetS or not by the aforementioned three definitions. Prostate volume, International Prostate Symptom Score, storage and voiding subscores, maximum urinary flow rate, and the postvoid urine of patients with and without MetS were compared separately in the three different groups. Surgical and medical treatment prevalence was also compared between three groups. No matter which definition was used, the International Prostate Symptom Score, the storage and voiding symptom scores, prostate volume, prostate-specific antigen, and postvoid urine were significantly higher in the patients with MetS. The maximum urinary flow rate was similar between patients with and without MetS, according to all three different definitions. There was no significant difference in the aforementioned parameter between patients with MetS diagnosed with the three different definitions. Irrespective of which definition was used, the surgical treatment rate was not significantly different in patients diagnosed with than without MetS, or between the patients with MetS diagnosed with the three different definitions. The authors suggest that it does not matter which of the aforementioned three definitions is used during the evaluation of MetS in men with BPE/LUTS.

2019 ◽  
Vol 13 (4) ◽  
pp. 155798831987038 ◽  
Author(s):  
Bing-Hui Li ◽  
Tong Deng ◽  
Qiao Huang ◽  
Hao Zi ◽  
Hong Weng ◽  
...  

The objective of this study was to evaluate association between body mass index (BMI) and prostate volume (PV), international prostate symptom scores (IPSS), maximum urinary flow rate ( Qmax), and post-void residual (PVR) of Chinese benign prostatic hyperplasia (BPH) patients. All newly diagnosed BPH patients between September 2016 and August 2018 were selected and 788 patients were included. According to BMI, the patients were categorized into four groups, while according to PV, IPSS, Qmax, and PVR, they were categorized into two groups based on clinical significant cutoffs. Univariable and multivariable logistic regressions and a restricted cubic spline (RCS) were applied to explore the relationship of BMI with categorical PV, IPSS, Qmax, and PVR. Compared with normal BMI, obesity presented significant association with increased risk of larger PV (>80 ml) in both unadjusted and adjusted models (unadjusted odds ratio [OR] = 1.772, 95% CI [1.201, 2.614], p = .004; adjusted OR = 1.912, 95% CI [1.212, 3.017], p = .005); however, underweight or overweight did not present a significant connection with such risk. No significant effect was identified for BMI on IPSS, Qmax, or PVR in either unadjusted or adjusted model. Nonlinear test including BMI using RCS and adjusting for confounders showed no significance ( p > .05); however, a significant linear relationship was ascertained between BMI and the risk of larger PV ( p < .001). In conclusion, there was a significant linear association between BMI and the risk of larger PV in BPH patients. Hence, this suggests urologists should consider both BMI and PV when providing surgical treatment for BPH patients.


2018 ◽  
Vol 24 (8) ◽  
pp. 6083-6086
Author(s):  
D Parikesit ◽  
C. A Mochtar ◽  
N Rasyid ◽  
R Umbas

To evaluate the relationship between IPP, age, prostate volume, uroflowmetry result, PSA, and IPSS. We retrospectively studied 162 patients presenting with LUTS suggestive of BPH between January 2012 and December 2014, analyzing age, IPP, pressure flow study, prostate volume, PSA, and International Prostate Symptom Score. IPP was classified into three stages: grade 1 (≤5 mm), grade 2 (5 mm < IPP ≤ 10 mm), and grade 3 (>10 mm). Statistical analysis included Kruskall-Wallis with Mann-Whitney as post hoc analysis and Spearman’s correlation coefficients were performed. The mean age was 67±7.7 years old. Achieved IPP values were the following: grade 1–40 (24.7%), grade 2–60 (37%), and grade 3–62 (38.3%). Results show statistically significant difference between IPP grades Qmax, PVR, and PV (p ≤ 0.05). Mean difference between IPP groups were significant using Mann-Whitney post hoc test for Qmax, PVR, and PV between IPP group 1 and 2, PV between IPP group 1 and 3, and Qmax, PVR, and PV between IPP group 2 and 3. Spearman’s correlations coefficient show positive correlation between IPP and PV (r = 0.506, p ≤ 0.05), PVR (r = 0.341, p ≤ 0.05), and PSA (r = 0.253, p ≤ 0.05). Intravesical prostate protrusion measured through abdominal ultrasound are a non-invasive and accessible method that significantly correlates with peak flow rate (Qmax), prostate volume, post void residue, and prostate specific antigen.


2015 ◽  
Vol 3 (1) ◽  
pp. 6-10 ◽  
Author(s):  
Ghanshyam Sigdel ◽  
WK Belokar

INTRODUCTION: Intravesical prostatic protrusion is a morphological change due to excessive growth of the median and lateral lobes of the prostate into the bladder in benign prostatic hyperplasia. It causes a 'ball-valve' type of obstruction during voiding. It is a useful parameter to assess the severity of the disease process, selection of treatment modality and its possible outcome in benign prostatic hyperplasia.MATERIAL AND METHODS: A prospective, non-randomized, observational study was carried out from January 2014 to June 2014 in the Department of Urology, College of Medical Sciences, Nepal. Total of 50 patients with benign prostatic hyperplasia were evaluated to assess the correlation of intravesical prostatic protrusion with international prostate symptom score, prostate volume, maximum flow rate and post void residual urine. Correlation between parameters of interest was quantified with Pearson correlation test.RESULTS: A positive correlation was demonstrated between intravesical prostatic protrusion, international prostate symptom score, prostate volume and post void residual urine. There was a negative correlation between intravesical prostatic protrusion and maximum flow rate.CONCLUSION: Intravesical prostatic protrusion is correlated with international prostate symptom score, prostate volume, maximum flow rate, and post void residual urine volume and hence can be used to assess the severity of benign prostatic hyperplasia.Journal of Universal College of Medical Sciences Vol. 3, No. 1, 2015: 6-10


1998 ◽  
Vol 160 (5) ◽  
pp. 1689-1694 ◽  
Author(s):  
JAN V. JEPSEN ◽  
GLEN LEVERSON ◽  
REGINALD C. BRUSKEWITZ

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