scholarly journals Treatment of Vertebral Artery Origin Stenosis with a Pharos Stent Device: A Single Center Experience

2011 ◽  
Vol 17 (3) ◽  
pp. 316-322 ◽  
Author(s):  
E. Broussalis ◽  
A.B. Kunz ◽  
G. Luthringshausen ◽  
S. Klein ◽  
M.R. McCoy ◽  
...  

Atherosclerotic stenosis of vertebral artery (VA) origin exceeding 70% severity accounts for one third of all vertebrobasilar strokes. For a period of one year the results of endovascular treatment of VA stenosis with the new Pharos stent device were assessed. Twenty-two patients with symptomatic VA stenosis were treated with the Pharos stent. Clinical status and stenosis grade were documented before treatment and 24 hours, one, three and twelve months after treatment via ultrasound and magnetic resonance tomography. All procedures proved to be technically successful without the occurrence of intra-procedural complications. During the observation period of more than one year, 55% of patients were documented with a mean stenosis degree of 60%: two (10%) of these patients showed a residual stenosis after angioplasty and nine patients (45%) an in-stent restenosis, whereas only two patients were documented with a hemodynamically relevant in-stent restenosis of 80%. These two patients were retreated with balloon dilatation. None of the patients showed neurological deterioration or new abnormalities at magnetic resonance tomography examination. Neither VA occlusion nor restenosis of the contralateral VA negatively affected the clinical outcome. An in-stent restenosis was developed by more female than male patients. VA origin stenting with the Pharos stent device is an effective treatment of stenosis. The good clinical results compared to the high restenosis rates have to be examined in further studies. Pin particular, it has to be determined whether the Pharos stent allows the vessel time for collateralization, whether double antiplatelet treatment prevents recurrent cerebrovascular events or whether merely the low restenosis degree is causative for the clinical outcome.

2010 ◽  
Vol 145 (3) ◽  
pp. 608-609
Author(s):  
Marcel A. Beijk ◽  
Bimmer E. Claessen ◽  
Karel T. Koch ◽  
José P.S. Henriques ◽  
Jan Baan ◽  
...  

2009 ◽  
Vol 15 (4) ◽  
pp. 462-465 ◽  
Author(s):  
G. Xu ◽  
X. Liu ◽  
L. Zheng ◽  
X. Fan ◽  
Q. Yin

In-stent restenosis or occlusion has been frequently reported as a complication after angioplasty and stenting in vertebral arteries. Reopening chronic in-stent occlusion in cervical arteries with endovascular techniques has not been reported. Here we describe a case with stent implantation in the origin of right vertebral artery. The stent was occluded one year after the procedure. The patient demonstrated concurrent ischemic symptoms which were relieved after the in-stent occlusion being recanalized successfully with re-angioplasty.


2017 ◽  
Vol 69 (6) ◽  
pp. 808-814
Author(s):  
Takayuki Yabe ◽  
Mikihoto Toda ◽  
Rine Nakanishi ◽  
Daiga Saito ◽  
Ippei Watanabe ◽  
...  

2020 ◽  
Vol 28 (3) ◽  
pp. 460-466
Author(s):  
Berkan Özpak

Background: In this study, we present one-year results of drug-eluting balloon treatment of femoropopliteal in-stent restenosis. Methods: A total of 62 patients (48 males, 14 females; mean age 64.2±9.1 years; range, 54 to 81 years) who underwent drug-eluting balloon stenting for femoropopliteal in-stent restenosis between August 2013 and October 2017 were included in the study. The patients were classified into three groups based on the narrowing length of stenosis in the stents. Group/Class 1 (n=17): narrowing <1/2 of the stent length; Group/Class 2 (n=22): narrowing >1/2 of the stent length, not totally occluded; and Group/Class 3 (n=23): totally occluded. In-stent restenosis was treated with drug-eluting balloon treatment. Results: There was a significant difference among all classes in terms of in-stent restenosis. The length of stenosis was a predictor for in-stent restenosis. The mean stent length was 107.7±24.6 mm in Group 1, 164.6±17.9 mm in Group 2, and 180±19.3 mm in Group 3. For non-occluded in-stent restenosis, restenosis rate at one year after balloon angioplasty was 47.1% in Group 1, 86.4% in Group 2, and 95.7% in Group 3. Femoropopliteal bypass was performed in five patients in whom treatment failed. None of the patients required amputation. Conclusion: The length of in-stent restenosis in the femoropopliteal arterial stents is an important predictor for recurrent stenosis, when re-flow is achieved with drug-eluting balloons.


2014 ◽  
Vol 553 ◽  
pp. 235-239
Author(s):  
Chang Yan Lin ◽  
Xiu Jian Liu ◽  
Yu Yang Liu ◽  
Chuang Ye Xu ◽  
Guang Hui Wu

The treatment of plaques near and involving coronary bifurcations (CB) is especially challenging, considering more plaques localized these regions and higher post-interventional in-stent restenosis (ISR) risk, mainly due to hemodynamic injury provoked on the arterial wall. Therefore optimization of stenting should begin with an understanding of how disease localized to these regions and why ISR formed associated with flow patterns. We chose four patients with bifurcation lesions, two patients with ISR and two without ISR according to the follow-up computed tomography angiography (CTA). Based on patient-specific pre-interventional and virtual stented geometries from CTA images, numerical simulation indicated that the wall shear stress (WSS) in stented segments, where the ISR occurred in one year, was lower than those without ISR, however. For bifurcation lesion, the stenting segments WSS is supposed a marker to forecast the ISR risk after stent treatment.


2013 ◽  
Vol 20 (2) ◽  
pp. 125-130 ◽  
Author(s):  
Yong-Juan Lin ◽  
Jing-Wei Li ◽  
Mei-Juan Zhang ◽  
Lai Qian ◽  
Wen-Jie Yang ◽  
...  

Sensors ◽  
2020 ◽  
Vol 20 (15) ◽  
pp. 4303
Author(s):  
Mokhalad Alghrairi ◽  
Nasri Sulaiman ◽  
Saad Mutashar

In-stent restenosis concerning the coronary artery refers to the blood clotting-caused re-narrowing of the blocked section of the artery, which is opened using a stent. The failure rate for stents is in the range of 10% to 15%, where they do not remain open, thereby leading to about 40% of the patients with stent implantations requiring repeat procedure within one year, despite increased risk factors and the administration of expensive medicines. Hence, today stent restenosis is a significant cause of deaths globally. Monitoring and treatment matter a lot when it comes to early diagnosis and treatment. A review of the present stent monitoring technology as well as the practical treatment for addressing stent restenosis was conducted. The problems and challenges associated with current stent monitoring technology were illustrated, along with its typical applications. Brief suggestions were given and the progress of stent implants was discussed. It was revealed that prime requisites are needed to achieve good quality implanted stent devices in terms of their size, reliability, etc. This review would positively prompt researchers to augment their efforts towards the expansion of healthcare systems. Lastly, the challenges and concerns associated with nurturing a healthcare system were deliberated with meaningful evaluations.


2017 ◽  
Vol 2017 ◽  
pp. 1-7 ◽  
Author(s):  
Dongyang Chen ◽  
Qiangqiang Li ◽  
Ye Sun ◽  
Jianghui Qin ◽  
Yao Yao ◽  
...  

Introduction. To investigate the clinical results of arthroscopic management for the unstable inferior leaf of the lateral meniscus anterior horn and associated cysts through an inframeniscal portal. Methods. From March 2005 to October 2014, 64 patients with an unstable inferior leaf of the lateral meniscus anterior horn and associated cysts underwent arthroscopic management with an inframeniscal portal. The mean age of the patients was 36.9 years (range, 18 to 49 years). The mean follow-up period was 28 months (range, 24 to 44 months). Clinical results were assessed using physical examination, the Lysholm knee score, and postoperative magnetic resonance scanning. Results. The median Lysholm score improved significantly at 1 year after surgery and at final follow-up. Magnetic resonance scanning at least one year after the operation revealed no recurrent meniscal tears or cysts. No reoperations were required after an average follow-up of 28 months. All patients reported significant symptomatic relief after the operation. They had full range of motion at three months and returned to normal activities and sports one year after surgery. Conclusion. The direct inframeniscal portal can provide an effective approach to manage lesions in the anterior horn of the lateral meniscus with predictable clinical outcomes.


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