scholarly journals 6-minute walking test: a useful tool in the management of heart failure patients

2019 ◽  
Vol 13 ◽  
pp. 175394471987008 ◽  
Author(s):  
Sophia Giannitsi ◽  
Mara Bougiakli ◽  
Aris Bechlioulis ◽  
Anna Kotsia ◽  
Lampros K. Michalis ◽  
...  

Reduced functional ability and exercise tolerance in patients with heart failure (HF) are associated with poor quality of life and a worse prognosis. The 6-minute walking test (6MWT) is a widely available and well-tolerated test for the assessment of the functional capacity of patients with HF. Although the cardiopulmonary exercise test (a maximal exercise test) remains the gold standard for the evaluation of exercise capacity in patients with HF, the 6MWT (submaximal exercise test) may provide reliable information about the patient’s daily activity. The current review summarizes the value of 6MWT in patients with HF and identifies its usefulness and limitations in everyday clinical practice in populations of HF. We aimed to investigate potential associations of 6MWD with other measures of functional status and determinants of 6MWD in patients with HF as well as to review its prognostic role and changes to various interventions in these patients.

e-CliniC ◽  
2021 ◽  
Vol 9 (1) ◽  
Author(s):  
Nurfadhilah H. Palilati ◽  
Frans E. N. Wantania ◽  
Linda W. A. Rotty

Abstract: Heart failure is a serious health problem and a leading cause of death, illness, and poor quality of life. Although the diagnosis and treatment of this disease has significant progress, the prognosis is still poor. The physical performance of patients with heart failure, for example, measured by a 6-minute walking test can be used to assess the functional capacity and assess the prognosis of the patient. This study was aimed to determine the relationship between physical performance and prognosis of patients with heart failure. This was a literature review study using literatures obtained from three databases, namely Pubmed, Science Direct, and Google Scholar. The keywords used in searching the literatures were "physical performance OR 6 minutes walking test AND heart failure prognosis" and their variations and translations. After the selection, 10 literatures were reviewed. The results showed that any decreases in distance of the 6-minute walking test and in walking speed would increase the risk of rehospitalization and mortality as reported in nine literatures. In conclusion, there was a significant relationship between physical performance and prognosis of patients with heart failure.Keywords: physical performance, prognosis of heart failure Abstrak: Gagal jantung merupakan masalah kesehatan yang serius dan penyebab utama kematian, kesakitan, serta kualitas hidup yang buruk. Meskipun diagnosis dan pengobatan penyakit ini telah mengalami banyak kemajuan namun prognosisnya masih buruk. Performa fisik pasien gagal jantung contohnya diukur dengan tes jalan 6 menit dapat digunakan untuk menilai kapasitas fungsional dan menilai prognosis dari pasien. Penelitian ini bertujuan untuk mengetahui hubungan performa fisik dengan prognosis pasien gagal jantung. Jenis penelitian ialah literature review menggunakan  literatur yang diperoleh dari tiga database yaitu Pubmed, Science Direct. dan Google Scholar. Kata kunci yang digunakan dalam pencarian artikel yaitu “physical performance OR 6 minutes walking test AND heart failure prognosis” dan berbagai variasi serta terjemahan. Hasil seleksi, mendapatkan 10 literature yang dikaji. Hasil penelitian mendapatkan bahwa setiap penurunan jarak yang ditempuh dalam uji jalan 6 menit dan penurunan waktu kecepatan berjalan dapat meningkatkan risiko rehospitalisasi dan kematian yang dilaporkan pada 9 literatur. Simpulan penelitian ini ialah terdapat hubungan bermakna antara performa fisik dengan prognosis pada pasien gagal jantung.Kata kunci: performa fisik, prognosis gagal jantung 


2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
T Chwyczko ◽  
L Zalucka ◽  
E Smolis-Bak ◽  
I Kowalik ◽  
E Noszczak ◽  
...  

Abstract Background Rehabilitation after LVAD implantation is increasingly used. We developed the novel method of comprehensive rehabilitation starting directly after LVAD implantation. Study group 21 recent LVAD (15 Heart Mate III, 6 HeartWare) recipients (56.2±11.7 yrs, 100% men) were included to 5-week rehabilitation program, which included supervised endurance training on cycloergometer (5 times per week), resistance training, general fitness exercises with elements of equivalent and coordination exercises (every day). 6-minute walking test (6MWT), cardiopulmonary exercise test (CPET) and prognostic biomarkers: NT-proBNP, Galectin-3 and ST2 were investigated at the beginning and at the end of rehabilitation program. Results See Table 1. At the end of rehabilitation program, significant increase in 6MWT distance, maximum workload, peak VO2 and upward shift of anaerobic threshold in CPET were observed in all patients. Significant reductions of NTproBNP, ST2 and galectin-3 levels were observed. There were no major adverse events during rehabilitaton. Conclusions Comprehensive novel rehabilitation in LVAD recipients is safe and results in significant improvement of 6-minutes walking test distance and cardiopulmonary exercise test results. Moreover, this novel rehabilitation program reduces levels of prognostic biomarkers of heart failure: NT-proBNP, Galectin-3 and ST2. Funding Acknowledgement Type of funding source: Public grant(s) – National budget only. Main funding source(s): National Center for Research and Development - STRATEGMED II project


2017 ◽  
Author(s):  
Mary N. Woessner ◽  
Itamar Levinger ◽  
Christopher Neil ◽  
Cassandra Smith ◽  
Jason D Allen

BACKGROUND Chronic heart failure is characterized by an inability of the heart to pump enough blood to meet the demands of the body, resulting in the hallmark symptom of exercise intolerance. Chronic underperfusion of the peripheral tissues and impaired nitric oxide bioavailability have been implicated as contributors to the decrease in exercise capacity in these patients. nitric oxide bioavailability has been identified as an important mediator of exercise tolerance in healthy individuals, but there are limited studies examining the effects in patients with chronic heart failure. OBJECTIVE The proposed trial is designed to determine the effects of chronic inorganic nitrate supplementation on exercise tolerance in both patients with heart failure preserved ejection fraction (HFpEF) and heart failure reduced ejection fraction (HFrEF) and to determine whether there are any differential responses between the 2 cohorts. A secondary objective is to provide mechanistic insights into the 2 heart failure groups’ exercise responses to the nitrate supplementation. METHODS Patients with chronic heart failure (15=HFpEF and 15=HFrEF) aged 40 to 85 years will be recruited. Following an initial screen cardiopulmonary exercise test, participants will be randomly allocated in a double-blind fashion to consume either a nitrate-rich beetroot juice (16 mmol nitrate/day) or a nitrate-depleted placebo (for 5 days). Participants will continue daily dosing until the completion of the 4 testing visits (maximal cardiopulmonary exercise test, submaximal exercise test with echocardiography, vascular function assessment, and vastus lateralis muscle biopsy). There will then be a 2-week washout period after which the participants will cross over to the other treatment and complete the same 4 testing visits. RESULTS This study is funded by National Heart Foundation of Australia and Victoria University. Enrolment has commenced and the data collection is expected to be completed in mid 2018. The initial results are expected to be submitted for publication by the end of 2018. CONCLUSIONS If inorganic nitrate supplementation can improve exercise tolerance in patients with chronic heart failure, it has the potential to aid in further refining the treatment of patients in this population. CLINICALTRIAL Australian New Zealand Clinical Trials Registry ACTRN12615000906550; https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=368912 (Archived by WebCite at http://www.webcitation.org/6xymLMiFK)


2018 ◽  
Vol 24 (8) ◽  
pp. S124-S125 ◽  
Author(s):  
Md. Mobashir Hasan Shandhi ◽  
Joanna Fan ◽  
Alex J. Heller ◽  
Mozziyar Etemadi ◽  
Omer T. Inan ◽  
...  

Author(s):  
Garrick C. Stewart

Heart failure is a complex clinical syndrome occurring in patients with an abnormality of cardiac structure or function that impairs the ability of the heart to fill with or eject blood. Patients with heart failure develop a constellation of symptoms (dyspnea and fatigue) and signs (edema and rales) that lead to frequent hospitalizations, poor quality of life, and a shortened life expectancy. Heart failure has also been defined as the failure of the heart to pump enough blood to meet the metabolic demands of the body, or the ability to do so only at elevated filling pressures. Congestive heart failure is the end stage for many cardiac diseases. Cardiomyopathy refers to any condition in which there is a structural abnormality of the myocardium itself.


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