scholarly journals Linked color imaging for the detection of early gastrointestinal neoplasms

2019 ◽  
Vol 12 ◽  
pp. 175628481988524 ◽  
Author(s):  
Satoshi Shinozaki ◽  
Hiroyuki Osawa ◽  
Yoshikazu Hayashi ◽  
Alan Kawarai Lefor ◽  
Hironori Yamamoto
Keyword(s):  
Gastrointestinal Endoscopy ◽  
Narrow Band ◽  
Narrow Band Imaging ◽  
Blue Laser ◽  
Gastrointestinal Neoplasms ◽  
Color Contrast ◽  
Color Imaging ◽  
Adenoma Detection ◽  
Blue Laser Imaging ◽  
Linked Color Imaging

In routine upper and lower gastrointestinal endoscopy, overlooking neoplastic lesions is inevitable even for well-trained endoscopists. Various methods have been reported to improve the detection of gastrointestinal neoplasms including chromoendoscopy, special endoscopes, and processor and image enhanced technologies. Equipment-based image enhanced endoscopy (e-IEE) using narrow band imaging (NBI) and blue laser imaging (BLI) is useful to characterize known lesions with magnification at a close-up view. However, they are not useful for the early detection of superficial, pale neoplasms, or both because of the weak image at a distant view in a wide lumen such as the stomach or colon. Linked color imaging (LCI) is a novel pre- and post-processing technology developed by Fujifilm Corporation that has sufficient brightness to illuminate a wide lumen. LCI delineates early gastric cancers as orange–red and intestinal metaplasia as purple. LCI improves the adenoma detection rate in the colon and decreases the polyp miss rate. LCI contributes to the detection of superficial lesions throughout the gastrointestinal tract by enhancing the color contrast between the neoplasm and the surrounding mucosa. LCI can distinguish them by their specific color allocation based mainly on the distribution of capillaries. The authors believe that moving forward, LCI should be used in routine upper and lower gastrointestinal endoscopy.

Magnifying Blue Laser Imaging versus Magnifying Narrow-Band Imaging for the Diagnosis of Early Gastric Cancer: A Prospective, Multicenter, Comparative Study

Digestion ◽  
2017 ◽  
Vol 96 (3) ◽  
pp. 127-134 ◽  
Author(s):  
Osamu Dohi ◽  
Nobuaki Yagi ◽  
Shigeto Yoshida ◽  
Shoko Ono ◽  
Yoji Sanomura ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Early Gastric Cancer ◽  
Comparative Study ◽  
Narrow Band ◽  
Narrow Band Imaging ◽  
Blue Laser ◽  
Laser Imaging ◽  
Blue Laser Imaging

scholarly journals A CNN CADx System for Multimodal Classification of Colorectal Polyps Combining WL, BLI, and LCI Modalities

2020 ◽  
Vol 10 (15) ◽  
pp. 5040 ◽  
Author(s):  
Roger Fonollà ◽  
Quirine E. W. van der Zander ◽  
Ramon M. Schreuder ◽  
Ad A. M. Masclee ◽  
Erik J. Schoon ◽  
...  
Keyword(s):  
Area Under The Curve ◽  
Colorectal Polyps ◽  
Blue Laser ◽  
Classification Model ◽  
Misclassification Rate ◽  
Laser Imaging ◽  
Color Imaging ◽  
Additional Information ◽  
Blue Laser Imaging ◽  
Linked Color Imaging

Colorectal polyps are critical indicators of colorectal cancer (CRC). Blue Laser Imaging and Linked Color Imaging are two modalities that allow improved visualization of the colon. In conjunction with the Blue Laser Imaging (BLI) Adenoma Serrated International Classification (BASIC) classification, endoscopists are capable of distinguishing benign and pre-malignant polyps. Despite these advancements, this classification still prevails a high misclassification rate for pre-malignant colorectal polyps. This work proposes a computer aided diagnosis (CADx) system that exploits the additional information contained in two novel imaging modalities, enabling more informative decision-making during colonoscopy. We train and benchmark six commonly used CNN architectures and compare the results with 19 endoscopists that employed the standard clinical classification model (BASIC). The proposed CADx system for classifying colorectal polyps achieves an area under the curve (AUC) of 0.97. Furthermore, we incorporate visual explanatory information together with a probability score, jointly computed from White Light, Blue Laser Imaging, and Linked Color Imaging. Our CADx system for automatic polyp malignancy classification facilitates future advances towards patient safety and may reduce time-consuming and costly histology assessment.

scholarly journals 252 – A Prospective Randomized Tandem Colonoscopy Study of Linked Color Imaging Or Narrow Band Imaging for Detection of Colorectal Polyp

2019 ◽  
Vol 156 (6) ◽  
pp. S-46-S-47
Author(s):  
Wai Keung Leung ◽  
Chuan-Guo Guo ◽  
Kwan-Lung Michael Ko ◽  
Wai Pan E. To ◽  
Lung-Yi Mak ◽  
...  
Keyword(s):  
Narrow Band ◽  
Narrow Band Imaging ◽  
Colorectal Polyp ◽  
Color Imaging ◽  
Linked Color Imaging

Blue laser imaging and linked color imaging improve the color difference value and visibility of colorectal polyps in underwater conditions

2020 ◽  
Vol 32 (5) ◽  
pp. 791-800 ◽  
Author(s):  
Yasushi Yamasaki ◽  
Keita Harada ◽  
Shumpei Yamamoto ◽  
Eriko Yasutomi ◽  
Shotaro Okanoue ◽  
...  
Keyword(s):  
Color Difference ◽  
Colorectal Polyps ◽  
Blue Laser ◽  
Laser Imaging ◽  
Color Imaging ◽  
Blue Laser Imaging ◽  
Linked Color Imaging

scholarly journals The Efficacy of Linked Color Imaging in the Endoscopic Diagnosis of Barrett’s Esophagus and Esophageal Adenocarcinoma

2020 ◽  
Vol 2020 ◽  
pp. 1-8
Author(s):  
Mamoru Tokunaga ◽  
Tomoaki Matsumura ◽  
Kentaro Ishikawa ◽  
Tatsuya Kaneko ◽  
Hirotaka Oura ◽  
...  
Keyword(s):  
Barrett’S Esophagus ◽  
Esophageal Adenocarcinoma ◽  
Barrett's Esophagus ◽  
Color Space ◽  
Color Difference ◽  
Blue Laser ◽  
Color Imaging ◽  
Color Differences ◽  
Blue Laser Imaging ◽  
Linked Color Imaging

Background. The present study aimed to evaluate the efficacy of linked color imaging (LCI) in diagnosing Barrett’s esophagus (BE) and esophageal adenocarcinoma (EAC). Methods. A total of 112 and 12 consecutive patients with BE and EAC were analyzed. The visibility scores of BE and EAC ranging from 4 (excellent visibility) to 0 (not detectable) were evaluated by three trainees and three experts using white light imaging (WLI), LCI mode, and blue laser imaging bright (BLI-b) mode. In addition, L ∗ a ∗ b ∗ color values and color differences ( Δ E ∗ ) were evaluated using the CIELAB color space system. Results. The visibility score of the BE in LCI mode ( 2.94 ± 1.32 ) was significantly higher than those in WLI ( 2.46 ± 1.48 ) and BLI-b mode ( 2.35 ± 1.46 ) ( p < 0.01 ). The color difference ( Δ E ∗ ) from the adjacent gastric mucosa in LCI mode ( 17.11 ± 8.53 ) was significantly higher than those in other modes ( 12.52 ± 9.37 in WLI and 11.96 ± 6.59 in BLI-b mode, p < 0.01 ). The visibility scores of EAC in LCI mode ( 2.56 ± 1.47 ) and BLI-b mode ( 2.51 ± 1.28 ) were significantly higher than that in WLI ( 1.64 ± 1.46 ) ( p < 0.01 ). The color difference ( Δ E ∗ ) from the adjacent normal Barrett’s mucosa in LCI mode ( 19.96 ± 7.97 ) was significantly higher than that in WLI ( 12.95 ± 11.86 ) ( p = 0.03 ). Conclusion. The present findings suggest that LCI increases the visibility of BE and EAC and contributes to the improvement of the detection of these lesions.

Linked color imaging reduces the miss rate of neoplastic lesions in the right colon: a randomized tandem colonoscopy study

Endoscopy ◽  
2018 ◽  
Vol 50 (04) ◽  
pp. 396-402 ◽  
Author(s):  
Silvia Paggi ◽  
Giuseppe Mogavero ◽  
Arnaldo Amato ◽  
Emanuele Rondonotti ◽  
Alida Andrealli ◽  
...  
Keyword(s):  
Color Contrast ◽  
Right Colon ◽  
Color Imaging ◽  
Colon Adenoma ◽  
Detection Rates ◽  
Adenoma Detection ◽  
Significant Difference ◽  
Neoplastic Lesions ◽  
Linked Color Imaging ◽  
The Right

Abstract Background Linked color imaging (LCI) is a newly developed image-enhancing endoscopy technology that provides bright endoscopic images and increases color contrast. We investigated whether LCI improves the detection of neoplastic lesions in the right colon when compared with high definition white-light imaging (WLI). Methods Consecutive patients undergoing colonoscopy were randomized (1:1) after cecal intubation into right colon inspection at first pass by LCI or by WLI. At the hepatic flexure, the scope was reintroduced to the cecum under LCI and a second right colon inspection was performed under WLI in previously LCI-scoped patients (LCI–WLI group) and vice versa (WLI–LCI group). Lesions detected on first- and second-pass examinations were used to calculate detection and miss rates, respectively. The primary outcome was the right colon adenoma miss rate. Results Of the 600 patients enrolled, 142 had at least one adenoma in the right colon, with similar right colon adenoma detection rates (r-ADR) in the two groups (22.7 % in LCI–WLI and 24.7 % in WLI–LCI). At per-polyp analysis, double inspection of the right colon in the LCI–WLI and WLI–LCI groups resulted in an 11.8 % and 30.6 % adenoma miss rate, respectively (P < 0.001). No significant difference in miss rate was found for advanced adenomas or sessile serrated lesions. At per-patient analysis, at least one adenoma was identified in the second pass only (incremental ADR) in 2 of 300 patients (0.7 %) in the LCI – WLI group and in 13 of 300 patients (4.3 %) in the WLI – LCI group (P = 0.01). Conclusions LCI could reduce the miss rate of neoplastic lesions in the right colon.

Comparison Between Linked Color Imaging and Blue Laser Imaging for Improving the Visibility of Flat Colorectal Polyps: A Multicenter Pilot Study

2019 ◽  
Vol 65 (7) ◽  
pp. 2054-2062
Author(s):  
Naohisa Yoshida ◽  
Takashi Hisabe ◽  
Hiroaki Ikematsu ◽  
Hiroshi Ishihara ◽  
Masaki Terasawa ◽  
...  
Keyword(s):  
Pilot Study ◽  
Colorectal Polyps ◽  
Blue Laser ◽  
Laser Imaging ◽  
Color Imaging ◽  
Blue Laser Imaging ◽  
Linked Color Imaging
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