scholarly journals A prospective study on the diagnosis of peripheral lung cancer using endobronchial ultrasonography with a guide sheath and computed tomography-guided transthoracic needle aspiration

2018 ◽  
Vol 10 ◽  
pp. 175883401775226 ◽  
Author(s):  
Jun Zhu ◽  
Feng Tang ◽  
Ye Gu
Keyword(s):  
Computed Tomography ◽  
Lung Cancer ◽  
Needle Aspiration ◽  
Detection Rates ◽  
Peripheral Lung Cancer ◽  
Lung Cancer Patients ◽  
Endobronchial Ultrasonography ◽  
Significant Difference ◽  
Peripheral Lung ◽  
A Prospective Study

Background: It is difficult to collect peripheral lung cancer samples. This study analyzed the applicability of endobronchial ultrasonography with a guide sheath (EBUS-GS) and computed tomography-guided transthoracic needle aspiration (CT-TTNA) for the diagnosis of peripheral lung cancer. Methods: A prospective analysis of peripheral lung cancer patients was performed. The study included 150 cases in the EBUS-GS group and 177 cases in the CT-TTNA group. The diagnostic rate, pathological type, genetic status and complications were analyzed. Results: The diagnosis rates were 64.0% and 97.7% in the EBUS-GS and CT-TTNA groups, respectively. The EBUS-GS group had undergone the most operations of the upper lobes of both lungs, while there was no significant difference in the operation distribution among the lobes in the CT-TTNA group. Adenocarcinoma (64 cases versus 51 cases) was most commonly observed in both groups, followed by squamous cell carcinoma. The detection rates of patients who were given a genetic test were 96.1% and 98.9% in the EBUS-GS and CT-TTNA groups, respectively. The incidence of complications in the EBUS-GS group was significantly less than that in the CT-TTNA group. Conclusions: EBUS-GS and CT-TTNA both had operational limitations. The diagnostic rate of EBUS-GS was lower than that of CT-TTNA, but there were fewer complications. CT-TTNA had better tolerance. According to the specific location of the lesion, we recommend EBUS-GS for lesions with a diameter ⩽30 mm and CT-TTNA for lesions with a diameter >30 mm. CT-TTNA specimens were advantageous for genetic testing.

scholarly journals Factors Associated with Diagnostic Yield of Endobronchial Ultrasonography with a Guide Sheath for Peripheral Lung Cancer

2016 ◽  
Vol 38 (1) ◽  
pp. 17-23 ◽  
Author(s):  
Keigo UCHIMURA ◽  
Kei YAMASAKI ◽  
Hiroshi ISHIMOTO ◽  
Sho KAKINOUCHI ◽  
Koki KIMURA ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Diagnostic Yield ◽  
Peripheral Lung Cancer ◽  
Factors Associated ◽  
Endobronchial Ultrasonography ◽  
Peripheral Lung

scholarly journals Preoperative Computed Tomography–Determined Sarcopenia and Postoperative Outcome After Surgery for Non-Small Cell Lung Cancer

2017 ◽  
Vol 107 (3) ◽  
pp. 244-251 ◽  
Author(s):  
E. Y. Kim ◽  
H. Y. Lee ◽  
K. W. Kim ◽  
J.-I. Lee ◽  
Y. S. Kim ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Lung Cancer ◽  
Overall Survival ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Disease Free Survival ◽  
Small Cell ◽  
Small Cell Lung ◽  
Lung Cancer Patients ◽  
Significant Difference

Background: Sarcopenia, reduced skeletal muscle mass, is associated with frailty, injuries, and mortality. The purpose of this study was to evaluate the impact of computed tomography–determined sarcopenia on surgical complications and outcomes after resection of non-small cell lung cancer. Methods: For a total 272 non-small cell lung cancer patients that underwent surgery between 2011 and 2016, cross-sectional area of muscle at the third lumbar vertebra (L3) was retrospectively measured using preoperative chest computed tomography images. Sarcopenia was defined as an L3 muscle index of <55 cm2/m2 for men and of <39 cm2/m2 for women. Clinical characteristics, postoperative complications, disease-free survival, and overall survival of patients with or without sarcopenia were compared. Results: A total of 60.3% ( n = 164) were male, and mean patient age was 62.9 ± 9.6 years. The prevalence of sarcopenia was 22.4% for all study subjects, 32.9% for men, and 6.5% for women. No significant difference was observed between patients with or without sarcopenia in terms of intensive care unit or hospital stay ( p = 0.502 and p = 0.378, respectively), and the presence of sarcopenia was not associated with postoperative complications. Furthermore, no significant difference was observed between the 3-year disease-free survival rate (74.3% vs 66.7%, p = 0.639) or 3-year overall survival rate (83.9% vs 87.7%, p = 0.563) of patients with or without sarcopenia. Conclusion: Sarcopenia as determined by preoperative computed tomography does not appear to have a negative impact on surgical outcome or overall survival for resected non-small cell lung cancer patients.

scholarly journals A prospective study of number of attempts required in conventional image guided transthoracic fine needle aspiration for pulmonary lesions

2019 ◽  
Vol 6 (3) ◽  
pp. 969
Author(s):  
Ramesh C. Sagar ◽  
K. V. Veerendra Kumar ◽  
S. D. Madhu ◽  
M. Malathi
Keyword(s):  
Computed Tomography ◽  
Lung Cancer ◽  
Fine Needle Aspiration ◽  
Needle Aspiration ◽  
Ct Guidance ◽  
Lung Lesions ◽  
Fine Needle ◽  
Pulmonary Lesions ◽  
Image Guided ◽  
Significant Difference

Background: With the established role of computed tomography (CT) screening for lung cancer, and the broad application of high-resolution CT, the solitary pulmonary nodule (SPN) are increasingly detected. The discovery rate of pulmonary lesions is evidently elevated these days: most of them are benign, but some of them are lung cancer. Lung cancer remains the leading cause of cancer deaths worldwide. The diagnosis of this pulmonary lesion is difficult and obtaining tissue samples to conduct pathology examination is the key point. Image guided transthoracic fine needle aspiration (TTFNA) of lung lesions is a well established, safe, and rapid method for achieving a definitive diagnosis for most lung lesions.Methods: TTFNA were performed in 160 patients attended the OPD and admitted due to pulmonary lesions between September 2016 and May 2017. After detailed characterization by computed tomography and compared with chest x-ray, TTFNA was done. Number of attempts, reasons for multiple attempts, and final FNAC diagnosis were recorded.Results: When CT guidance was used sufficient material was obtained in 91.03% of patients, but with USG guidance insufficient material was reason for repeated attempts in nearly 25.25% of cases. Bloody aspirate was reason in total 13.54% patients and there was no significant difference between CT guidance and USG guidance (14.29% v/s 13.13% respectively). Again only inflammatory cells was reason for repeated attempts, in CT guidance 8.93% and in USG guidance 20.20%, attributed to localization of needle in both techniques.Conclusions: CT guided FNAC should be considered in diagnosis of lung lesions if computerized tomography is not contraindicated. Further, routine need for advanced imaging techniques like 3D computerized tomographic study for localizing lesions in lung to reduce the number of attempts should be considered.

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