Bannaxanthone E Induced Cell-Cycle Arrest and Apoptosis in Human Lung Cancer Cell Line
2021 ◽
Vol 16
(11)
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pp. 1934578X2110590
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The anti-cancer activity of bannaxanthone E isolated from Garcinia mckeaniana leaves was assessed through a flow cytometric method on human lung SK-LU-1 cancer cells, including cell cycle changes and induction of cell apoptosis. Treatment with bannaxanthone E led to the suppression of cell cycle progression at the G2/M phase to 19.6% at 4 µM, and induced apoptosis via cell morphological changes, increased the fluorescence signal in caspase-3/7 activation, and accumulation of apoptotic cells in the SK-LU-1 line at 4 µM to 25.7%.
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2012 ◽
Vol 27
(2)
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pp. 113-118
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2011 ◽
Vol 31
(10)
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pp. 1091-1095
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2004 ◽
Vol 33
(2)
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pp. 287-290
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2004 ◽
Vol 33
(8)
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pp. 1237-1245
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2020 ◽
Vol 18
(7)
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pp. 483-490
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