Nonepileptic Myoclonus in COVID-19: Case Report

In late 2019, the novel coronavirus, SARS-CoV-2, and the disease it causes, COVID-19, was identified. Since then many different neurological manifestations of COVID-19 have been well reported. Movement abnormalities have been rarely described. We report here a critically ill patient with COVID-19 who developed generalized myoclonus during the recovery phase of the infection. Myoclonus was associated with cyclical fevers and decreased alertness. Movements were refractory to conventional anti-epileptic therapies. There was concern that myoclonus could be part of a post-infectious immune-mediated syndrome. The patient improved fully with a 4-day course of high-dose steroids. Our experience highlights a rare, generalized myoclonus syndrome associated with COVID-19 that may be immune-mediated and is responsive to treatment.

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Hemisferic encephalic involviment associated with sars- cov-2

10.5327/1516-3180.005 ◽

2021 ◽

Author(s):

Maria Clara Carvalho Silva de Amorim ◽

Karla Oliveira Couto ◽

Pedro José da Silva Júnior ◽

Thiago Gonçalves Fukuda ◽

Pedro Antônio Pereira de Jesus ◽

...

Keyword(s):

Case Report ◽

Severe Acute Respiratory Syndrome ◽

Respiratory Disease ◽

Critically Ill ◽

Clinical Presentation ◽

Neurological Complications ◽

Metabolic Changes ◽

The Novel ◽

Immunological Reaction ◽

Neurological Manifestations

Context: The novel severe acute respiratory syndrome coronavirus 2 (SARSCoV-2) emerged in Wuhan, China and rapidly spread worldwide. Although the predominant clinical presentation is with respiratory disease, neurological manifestations are being recognised increasingly. Case report: In this report, we demonstrate a case of hemispheric brain in volvement as a neurological manifestation of Sars-cov-2 in a 74-year-old patient admitted to Hospital Santa Izabel (HSI) between May and July 2020. Conclusion: In COVID-19, although the predominant clinical presentation is with respiratory disease, neurological complications have been reported. Severe neurological complications are either because of direct viral invasion, immunological reaction, or hypoxic metabolic changes. The patients with encephalitis are usually severely or critically ill.

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Henoch–Schoenlein Purpura Following Severe Acute Respiratory Syndrome Coronavirus-2 Infection: A Case Report and Short Review of Histopathological Changes in Dermis

10.22541/au.161148965.52528385/v1 ◽

2021 ◽

Author(s):

Saeed Soleiman-Meigooni ◽

Ramin Hamidi-Farahani ◽

Mousa Ahmadi ◽

Ali Asgari ◽

Ramin Yaghmaee

Keyword(s):

Abdominal Pain ◽

Case Report ◽

Severe Acute Respiratory Syndrome ◽

Short Review ◽

The Novel ◽

Histopathological Changes ◽

Immune Mediated ◽

Novel Coronavirus ◽

Purpuric Rash

As the novel Coronavirus pandemic continues to affect people worldwide, immune-mediated inflammatory syndromes have been reporting related to this virus. We presented a case of novel Coronavirus pneumonia, who developed a purpuric rash, abdominal pain, and hematuria, diagnosed with Henoch–Schoenlein purpura.

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Acute motor-sensory axonal polyneuropathy variant of Guillain–Barre syndrome complicating the recovery phase of coronavirus disease 2019 infection: a case report

Journal of Medical Case Reports ◽

10.1186/s13256-021-02988-y ◽

2021 ◽

Vol 15 (1) ◽

Author(s):

Ahmed Maseh Haidary ◽

Sarah Noor ◽

Esmatullah Hamed ◽

Tawab Baryali ◽

Soma Rahmani ◽

...

Keyword(s):

Recovery Phase ◽

Sudden Onset ◽

Therapeutic Interventions ◽

Guillain Barre Syndrome ◽

The Novel ◽

Case Presentation ◽

Progressive Muscle Weakness ◽

Guillain Barré Syndrome ◽

Novel Coronavirus ◽

Guillain Barré

Abstract Introduction The novel coronavirus, since its first identification in China, in December 2019, has shown remarkable heterogeneity in its clinical behavior. It has affected humans on every continent. Clinically, it has affected every organ system. The outcome has also been variable, with most of the older patients showing grave outcomes as compared with the younger individuals. Here we present a rare and severe variant of Guillain–Barre syndrome that complicated the disease in recovery phase. Case presentation A 60-year-old Afghan man, who had been recovering from symptoms related to novel coronavirus associated disease, presented with sudden onset of progressive muscle weakness and oxygen desaturation. Electrophysiological workup confirmed the diagnosis of Guillain–Barre syndrome, and early institution of intravenous immunoglobulin resulted in complete resolution. Conclusion Guillain–Barre syndrome has recently been reported in many patients diagnosed with novel coronavirus associated disease. While clinical suspicion is mandatory to guide towards an effective diagnostic workup, early diagnosis of this complication and timely institution of therapeutic interventions are indispensable and lifesaving.

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Pneumocystis and SARS-CoV-2 Co-Infection: A Case Report and Review of an Emerging Diagnostic Dilemma

Open Forum Infectious Diseases ◽

10.1093/ofid/ofaa633 ◽

2020 ◽

Author(s):

Carlos Rubiano ◽

Kathleen Tompkins ◽

Subhashini A Sellers ◽

Brian Bramson ◽

Joseph Eron ◽

...

Keyword(s):

Case Report ◽

Critically Ill ◽

Therapeutic Strategies ◽

Pneumocystis Jirovecii ◽

Critically Ill Patient ◽

Pneumocystis Jirovecii Pneumonia ◽

Diagnostic Dilemma

Abstract We present a case of a critically ill patient with COVID-19 found to have AIDS and Pneumocystis jirovecii pneumonia (PCP). COVID-19 and PCP co-occurrence is increasingly reported and may complicate diagnostic and therapeutic strategies. Patients with severe COVID-19 should be screened for underlying immunocompromise and coinfections should be considered.

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