An Assessment of Concentrations of Soluble CD4 and CD8 Receptors in Serum before and after Surgical Treatment in Patients with Chronic Maxillary Sinusitis

2003 ◽  
Vol 17 (3) ◽  
pp. 123-126
Author(s):  
Jurek Olszewski ◽  
Wiesław Chudzik ◽  
Kazimierz Wiśniewski ◽  
Jarosław Miłonski ◽  
Robert Matyja
Keyword(s):  
Surgical Treatment ◽  
Maxillary Sinusitis ◽  
Receptor Expression ◽  
Assay Method ◽  
Control Groups ◽  
Group I ◽  
Before And After ◽  
Chronic Maxillary Sinusitis ◽  
Soluble Cd4 ◽  
Maxillary Sinuses

Background The aim of this study was to assess the concentrations of soluble CD4 (sCD4) and sCD8 receptors in serum of patients before and after surgical treatment of chronic maxillary sinusitis. Methods We examined 57 patients, aged 20–63 years (mean age, 41 ± 0.5 years), and divided them into four groups: group I, 14 patients with chronic maxillary sinusitis without allergy; group II, 15 patients with chronic maxillary sinusitis with allergy; group III, 16 patients with cyst of maxillary sinuses without allergy (control); and group IV, 12 patients with cyst of maxillary sinuses with allergy (control). The assay of sCD4 and sCD8 receptor concentrations was performed by means of enzyme-linked immunosorbent assay method. The concentrations of sCD4 and sCD8 receptors before and after 30 days of surgical treatment of maxillary sinuses were examined. Results In our studies the increase of concentration of sCD4 in groups I and II in comparison with the concentration in control groups were statistically significant. The differences between mean concentrations of sCD8 in groups I and II and in the control groups were not statistically significant. After surgical treatment of chronic maxillary sinusitis, a significant decrease in values of sCD4 and sCD8 in comparison with the results before surgical treatment suggest that the measurement of cell suppression product concentration can be used to assess the extirpation of the inflammatory process and the effectiveness of the operation method. Conclusion Changes in concentration of sCD4 and sCD8 manifest activation or suppression of cells with particular receptor expression.

Bacteriology of Chronic Maxillary Sinusitis and Normal Maxillary Sinuses: Using Culture and Multiplex Polymerase Chain Reaction

2003 ◽  
Vol 17 (3) ◽  
pp. 143-147 ◽  
Author(s):  
M. Tayyar Kalcioglu ◽  
Bengul Durmaz ◽  
Elif Aktas ◽  
Orhan Ozturan ◽  
Riza Durmaz
Keyword(s):  
Maxillary Sinusitis ◽  
Control Group ◽  
Study Group ◽  
Control Groups ◽  
Coagulase Negative Staphylococci ◽  
Detection Rates ◽  
Chronic Maxillary Sinusitis ◽  
Polymerase Chain ◽  
And Control ◽  
Maxillary Sinuses

Background Although many investigations have been performed on bacteriology of chronic sinusitis and normal sinuses, there still is much discussion. Also a new bacterial agent, Alloiococcus otitidis determined in the nasopharynx and middle ear specimens can be thought as a causative agent of sinusitis. Methods The bacteriology of chronic maxillary sinusitis and maxillary sinuses with normal radiogram and endoscopic findings were studied by culture methods for aerobic and anaerobic bacteria. Multiplex polymerase chain reaction (PCR) was used to investigate four bacteria in study and control groups. There were 27 specimens in the study group and 28 specimens in the control group. Results In the study group, the bacteria commonly isolated were Staphylococcus aureus (11.1%), α-hemolytic streptococci (11.1%), Streptococcus pneumoniae (11.1%), Haemophilus influenzae (7.4%), coagulase-negative staphylococci (7.4%), and anaerobes (33.3%). Coagulase-negative staphylococci (14.3%), α-hemolytic streptococci (10.7%), and anaerobes (35.7%) were isolated also in the control group. PCR was used to investigate S. pneumoniae, H. influenzae, Moraxella catarrhalis, and A. otitidis in the study and control groups. None of these bacteria was determined in the control group whereas detection rates of these bacteria in the study group were 11.1, 11.1, 3.7, and 7.4%, respectively. It should be considered that PCR yielded faint amplification band for A. otitidis. Conclusion Using multiplex PCR can help to increase detection rates of bacterial etiology. Healthy sinuses are not sterile. A. otitidis may be one of the pathogens causing sinusitis.

scholarly journals The Use of Computed Tomography for the Study of Chronic Maxillary Sinusitis: Based on Crania from the Pucará De Tilcara Fortress, Argentina

2020 ◽  
Vol 48 (3) ◽  
pp. 143-153
Author(s):  
A. V. Zubova ◽  
N. I. Ananyeva ◽  
V. G. Moiseyev ◽  
I. K. Stulov ◽  
L. M. Dmitrenko ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Maxillary Sinusitis ◽  
Secondary Infection ◽  
Ostiomeatal Complex ◽  
Odontogenic Origin ◽  
X Ray Computed ◽  
Chronic Maxillary Sinusitis ◽  
Relationship Of ◽  
Skeletal Samples ◽  
Maxillary Sinuses

We discuss the methodological advantages of using X-ray computed tomography (CT) for diagnosing chronic maxillary sinusitis (CMS) of various etiologies on skeletal samples. A CT examination of 20 crania from the Pucará de Tilcara fortress, Argentina (late 8th to 16th centuries AD), was carried out. Criteria for identifying CMS included osteitic lesions in the form of focal destruction, and thickened and sclerotized walls of maxillary sinuses. To determine the etiology of the disease, a tomographic and macroscopic examination of the dentition and bones of the ostiomeatal complex were performed, the presence or absence of facial injuries was assessed, and the co-occurrence of various pathologies was statistically evaluated. Five cases of CMS were identified. Four of these may be of odontogenic origin; in two cases, a secondary infection of the maxillary sinuses is possible. In one instance, the etiology was not determined. No indications of traumatic infection were found. Statistical analysis revealed a relationship of CMS with apical periodontitis and the ante-mortem loss of upper molars and premolars. An indirect symptom of CMS may be the remodeled bone tissue and porosity of the posterior surface of the maxilla.

Bacteriology of Chronic Maxillary Sinusitis in Adults

1989 ◽  
Vol 98 (6) ◽  
pp. 426-428 ◽  
Author(s):  
Itzhak Brook
Keyword(s):  
Staphylococcus Aureus ◽  
Chronic Sinusitis ◽  
Maxillary Sinusitis ◽  
Anaerobic Bacteria ◽  
Chronic Maxillary Sinusitis ◽  
Aerobic And Anaerobic ◽  
And Staphylococcus Aureus ◽  
Culture Positive ◽  
Maxillary Sinuses

Aspirates of 72 chronically inflamed maxillary sinuses were processed for aerobic and anaerobic bacteria. Bacterial growth was present in 66 of the 72 specimens (92%). Anaerobic bacteria were isolated in 58 of the 66 culture-positive specimens (88%). Anaerobes only were recovered in 37 cases (56%) and in 21 (32%) they were mixed with aerobic or facultative bacteria. Aerobic or facultative bacteria were present in eight cases (12%). A total of 185 isolates (2.8 per specimen) — 131 (2.0 per specimen) anaerobes and 54 (0.8 per specimen) aerobes or facultatives — were isolated. The predominant anaerobic organisms were anaerobic cocci and Bacteroides sp, and the predominant aerobes or facultatives were Streptococcus sp and Staphylococcus aureus. Twelve of the 27 Bacteroides sp that were tested for β-lactamase (44%) produced the enzyme. These findings indicate the major role of anaerobic organisms in chronic sinusitis.

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