The management of pancreatic metastasis from synovial sarcoma of the soft tissue: A case report

Pancreatic metastases are rare, accounting for 2%–3% of pancreatic tumors. The pancreas represents an unusual metastatic site of synovial sarcoma (SS) outside the usual localizations (regional nodes, lung, bone, and liver). The diagnosis is evoked by the personnel medical history of SS and imaging then confirmed by histological examination of the guided pancreatic biopsy. Its therapeutic management is mainly surgical with extensive removal of the lesion. So far only four cases have been reported in the English literature. We reported the case of a male aged 30-year-old who was admitted to our Institute for a local recurrence of SS of the left thigh which was initially treated by surgical excision. The patient underwent a wide surgical excision followed by chemotherapy and radiotherapy. About 15 months later, he experienced a pancreatic metastasis of his SS. He had a caudal splenopancreatectomy with partial resection of the transverse colon followed by chemotherapy. This report highlights the diagnostic difficulties of this rare localization and therapeutic challenge.

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Recurrent Episodic Foot-Drop Following Surgery to the Thigh

Sarcoma ◽

10.1155/2000/949842 ◽

2000 ◽

Vol 4 (4) ◽

pp. 183-184 ◽

Cited By ~ 1

Author(s):

Srinivas Maiya ◽

Simon Tan ◽

Robert J. Grimer

Keyword(s):

Soft Tissue ◽

Soft Tissue Sarcoma ◽

Case History ◽

Surgical Excision ◽

Left Thigh ◽

Foot Drop ◽

Complete Relief ◽

History Of

Subject.We present the case history of a 47-year-old lady who, 10 months following excision of a soft tissue sarcoma from the left thigh, was struck with recurrent episodes of foot drop.Discussion.The curious phenomenon of recurrent foot drop was found to be secondary to pressure symptoms from a tense seroma of the thigh. She underwent surgical excision of the sac and had immediate and complete relief of symptoms.

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Pancreatic Metastasis of High-Grade Papillary Serous Ovarian Carcinoma Mimicking Primary Pancreas Cancer: A Case Report

Case Reports in Medicine ◽

10.1155/2012/943280 ◽

2012 ◽

Vol 2012 ◽

pp. 1-3 ◽

Cited By ~ 2

Author(s):

Yusuf Gunay ◽

Ebru Demiralay ◽

Alp Demirag

Keyword(s):

Ovarian Cancer ◽

Cystic Lesion ◽

Pancreatic Neoplasm ◽

Pancreatic Mass ◽

Pancreatic Tumors ◽

Pancreatic Metastasis ◽

High Grade ◽

Ovarian Carcinomas ◽

Serous Adenocarcinoma ◽

History Of

Introduction. Reports of epithelial ovarian carcinomas metastatic to the pancreas are very rare. We herein present a metastasis of high grade papillary serous ovarian cancer to mid portion of pancreas.Case. A 42-year-old patient was admitted with a non-specified malignant cystic lesion in midportion of pancreas. She had a history of surgical treatment for papillary serous ovarian adenocarcinoma. A cystic lesion was revealed by an abdominal computerized tomography (CT) performed in her follow up . It was considered as primary mid portion of pancreatic cancer and a distal pancreatectomy was performed. The final pathology showed high-grade papillary serous adenocarcinoma morphologically similar to the previously diagnosed ovarian cancer.Discussion. Metastatic pancreatic cancers should be considered in patients who present with a solitary pancreatic mass and had a previous non-pancreatic malignancy. Differential diagnosis of primary pancreatic neoplasm from metastatic malignancy may be very difficult. A biopsy for tissue confirmation is required to differentiate primary and secondary pancreatic tumors. Although, the value of surgical resection is poorly documented, resection may be considered in selected patients.Conclusion. Pancreatic metastasis of ovarian papillary serous adenocarcinoma has to be kept in mind when a patient with pancreatic mass has a history of ovarian malignancy.

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Solitary Colorectal Cancer Metastasis to the Pancreas

Case Reports in Surgery ◽

10.1155/2019/4891512 ◽

2019 ◽

Vol 2019 ◽

pp. 1-3

Author(s):

M. Karageorgou ◽

D. Myoteri ◽

T. Kotsis ◽

G. Polymeneas ◽

E. Bournakis ◽

...

Keyword(s):

Metastatic Disease ◽

Cancer Metastasis ◽

Rectal Adenocarcinoma ◽

Neoadjuvant Chemoradiotherapy ◽

Tumor Board ◽

Pancreatic Tumors ◽

Pancreatic Metastasis ◽

Solid Organ ◽

En Bloc ◽

History Of

Introduction. Secondary pancreatic metastasis from other solid organ malignancy is rare and accounts for less than 2% of all pancreatic tumors. The aim of this study is to highlight that colorectal metastatic disease in the pancreas could be in selected cases an indication for surgery rather than for palliative chemotherapy. Case Presentation. We present a case of a 62-year-old Caucasian female with a history of rectal adenocarcinoma. Four years ago, the patient underwent low anterior resection of the rectosigmoid, post neoadjuvant chemoradiotherapy, with adjuvant chemotherapy. During her follow-up, imaging examinations revealed a lesion in the pancreatic neck with features indicating primary pancreatic cancer. Near-total distal pancreatectomy with en bloc splenectomy was performed. Histopathology revealed metastatic disease compatible with colorectal adenocarcinoma as the primary cancer. Second-line chemotherapy was decided from the institutional tumor board. The patient remains disease free one year later. Conclusion. Pancreatic lesions in patients with a history of extrapancreatic malignancy should raise suspicions of metastatic disease. Surgical intervention is a legitimate treatment option for these pancreatic lesions, since they represent solitary disease deposits and of course in the context of multidisciplinary meeting decisions, and after proper and extensive staging investigations.

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Chronic Contained Rupture of Abdominal Aortic Aneurysm Presenting with Longstanding Back Pain

Scottish Medical Journal ◽

10.1177/003693300505000310 ◽

2005 ◽

Vol 50 (3) ◽

pp. 122-123 ◽

Cited By ~ 2

Author(s):

J Al-Koteesh ◽

Y Masannat ◽

N V M James ◽

U Sharaf

Keyword(s):

Abdominal Aortic Aneurysm ◽

Back Pain ◽

Aortic Aneurysm ◽

Rare Event ◽

Left Thigh ◽

Low Back ◽

Abdominal Aortic ◽

Diagnostic Difficulties ◽

History Of ◽

Recurrent Low Back Pain

Abdominal aortic aneurysm (AAA) is one of the important differential diagnoses of back pain which is often missed. Chronic contained rupture is a rare event that can cause diagnostic difficulties, presenting in different ways such as back pain, neuropathy or groin mass. We are presenting a case of 46-year-old man who presented with history of recurrent low back pain radiating to his left leg, associated with sensory deficit in the left thigh. His complaint proved to be resulting from chronic contained AAA leak.

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Pancreatic metastasis of mesenchymal chondrosarcoma

International Surgery Journal ◽

10.18203/2349-2902.isj20205374 ◽

2020 ◽

Vol 7 (12) ◽

pp. 4164

Author(s):

Cristina P. Camacho ◽

Emília C. Fraga ◽

Ana Almeida ◽

Maria J. Amaral ◽

Mario Sergio

Keyword(s):

Computed Tomography ◽

Chondrogenic Differentiation ◽

Pulmonary Metastases ◽

Surgical Excision ◽

Left Thigh ◽

Mesenchymal Chondrosarcoma ◽

Pancreatic Metastasis ◽

Pancreatic Tail ◽

Aggressive Tumor

Mesenchymal chondrosarcoma is an aggressive tumor with chondrogenic differentiation that typically develops in skeletal sites, such as craniofacial bones, ribs, ilium, femur, and the vertebrae. It counts less than 3% of primary chondrosarcomas, and about a third of these tumors develop extraskeletal sites such as the meninges, and soft tissue. We present a case of a 53-year-old female, that was diagnosed with mesenchymal chondrosarcoma in the left thigh and submitted to surgical excision. The patient's case was evaluated by a multidisciplinary team, and it was decided to maintain vigilance. In the 5 years, follow-up presented several pulmonary metastases that were submitted to pulmonary resections. Two years later, during imaging control, an abdominal computed tomography (CT) scan was performed and revealed a pancreatic mass of 3 centimeters, located in the pancreatic tail. The patient was submitted to an explorative laparoscopy and a distal pancreatectomy was performed. The biopsy gave the definitive result of the metastasis of mesenchymal chondrosarcoma.

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Pancreatic Metastasis from Prostate Cancer

Case Reports in Medicine ◽

10.1155/2010/826273 ◽

2010 ◽

Vol 2010 ◽

pp. 1-2 ◽

Cited By ~ 5

Author(s):

Julian Jacob ◽

Cyrus Chargari ◽

Olivier Bauduceau ◽

Maryse Fayolle ◽

Bernard Ceccaldi ◽

...

Keyword(s):

Prostate Cancer ◽

Diagnostic Delay ◽

Exceptional Case ◽

Metastatic Spread ◽

Pancreatic Tumors ◽

Pancreatic Metastasis ◽

Colorectal Cancers ◽

Pancreatic Metastases ◽

Appropriate Treatment ◽

Timely Delivery

The pancreas is an unusual location for metastases from other primary cancers. Rarely, pancreatic metastases from kidney or colorectal cancers have been reported. However, a variety of other cancers may also spread to the pancreas. We report an exceptional case of pancreatic metastasis from prostate cancer. Differences in management between primary and secondary pancreatic tumors make recognition of metastases to the pancreas an objective of first importance. Knowledge of unusual locations for metastatic spread will reduce diagnostic delay and lead to a timely delivery of an appropriate treatment.

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