Risk-adjusted versus overall blood pressure control rate for identifying the need for intensified cardiovascular risk reduction: lessons from a cross-sectional study

2012 ◽  
Vol 20 (6) ◽  
pp. 972-979 ◽  
Author(s):  
Jürgen in der Schmitten ◽  
Karl Wegscheider ◽  
Heinz-Harald Abholz ◽  
Achim Mortsiefer
Keyword(s):  
Blood Pressure ◽  
Cardiovascular Risk ◽  
Risk Reduction ◽  
Blood Pressure Control ◽  
Pressure Control ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cardiovascular Risk Reduction ◽  
Cross Sectional ◽  
Blood Pressure Control Rate

scholarly journals Glutathione S-transferase M1 and T1 Genes Deletion Polymorphisms and Blood Pressure Control Among Treated Essential Hypertensive Patients in Burkina Faso.

2020 ◽  
Author(s):  
Herman Karim SOMBIE ◽  
Daméhan Tchélougou ◽  
Pegdwendé Abel Sorgho ◽  
Jonas Koudougou Kologo ◽  
Abdoul Karim OUATTARA ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Essential Hypertension ◽  
Burkina Faso ◽  
Blood Pressure Control ◽  
Pressure Control ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Gstm1 Gene ◽  
Significant Difference

Abstract ObjectiveGlutathione S-transferases have been associated with experimental resistance to some drugs. The present study investigated the factors associated with blood pressure control in patients with essential hypertension, especially the role of GSTT1 and GSTM1 genes polymorphisms. This cross-sectional study in Burkina Faso consisted of 200 patients with essential hypertension and under treatment. ResultsThis cross-sectional study population consisted of 57.5 % (115/200) of patients with their hypertension under control. No statistically significant difference (p > 0.05) was found between controlled and uncontrolled (SBP and/or DBP) groups for anthropometric and biochemical parameters as well as for GSTT1 or GSTM1 gene polymorphisms. However, current alcohol consumption (OR = 3.04; CI = 1.88 - 6.13; p < 0.001), physical inactivity (OR = 3.07; CI = 1.71 - 5.49; p < 0.001), severity of hypertension (Grade III [OR = 3.79; CI = 2.00 - 7.17; p < 0.001]) and heart damage (OR = 3, 14; CI = 1.59 - 6.02; p < 0.001) were statistically more frequent in uncontrolled essential hypertension group than controlled group.

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