scholarly journals Delivery room triage of large for gestational age infants of diabetic mothers

2014 ◽  
Vol 2 ◽  
pp. 205031211452728 ◽  
Author(s):  
Leandro Cordero ◽  
Krista Rath ◽  
Katherine Zheng ◽  
Mark B Landon ◽  
Craig A Nankervis
Keyword(s):  
Gestational Age ◽  
Delivery Room ◽  
Large For Gestational Age ◽  
Infants Of Diabetic Mothers ◽  
Diabetic Mothers

269: Delivery outcomes of large for gestational age (LGA) infants of diabetic mothers (IDMs)

2013 ◽  
Vol 208 (1) ◽  
pp. S123
Author(s):  
Kara Markham ◽  
Krista Rath ◽  
Katherine Zheng ◽  
Celeste Durnwald ◽  
Stephen Thung ◽  
...  
Keyword(s):  
Gestational Age ◽  
Large For Gestational Age ◽  
Infants Of Diabetic Mothers ◽  
Delivery Outcomes ◽  
Diabetic Mothers

scholarly journals Neonatal Outcomes of Large-for-Gestational Age Infants with or without Gestational Diabetes Mellitus

2018 ◽  
Vol 16 (2) ◽  
pp. 25-30
Author(s):  
Taslima Begum ◽  
Gulshan Ara Begum ◽  
Mahmood A Chowdhury ◽  
Wazir Ahmed ◽  
Md Badrudddoza
Keyword(s):  
Blood Glucose ◽  
Birth Weight ◽  
Gestational Diabetes ◽  
Respiratory Distress ◽  
Hospital Stay ◽  
Gestational Age ◽  
Neonatal Outcomes ◽  
Large For Gestational Age ◽  
Infants Of Diabetic Mothers ◽  
Diabetic Mothers

Background: Infants are considered Large for Gestational Age (LGA)if their birth weight is greater than the 90th percentile for gestational age. Birth weight is influenced by a number of factors with maternal diabetes being one of the most common risk factor affecting birth weight. They have an increased risk for adverse perinatal outcomes. The aim of the present study was to compare the neonatal outcomes of LGA infants delivered by women with and without gestational diabetes mellitus.Methods: This is a prospective study of all live-born LGA infants of 37 weeks of gestation with a birth weight of 4000g admitted at Neonatal ward of Chattagram Maa Shishu-O-General Hospital (CMSOGH) between 1st August 2013 to 31st July 2014. Type of sampling was purposive convenient sampling. A total of 51 neonatal patients were included. Data was collected in case record form. Data collected for the mothers included age, parity, gestational age and mode of delivery. Data for the infants include sex, birth weight, birth length and laboratory test. Outcomes were compared between infants of diabetic mothers (Group A) and infants of non- diabetic mothers (Group B). Then data was analyzed by SPSS 17.0 program and presented by tabular method, diagram and chart.Results: Among fifty one study subjects, thirty were Infants of Diabetic Mothers (IDMs) while twenty one were non- IDMs. 19 (63.3%) of the IDMs were male while 11 (36.7%) were female. Among the 21 non-IDMs 10 (47.6%) were male and 11 (52.4%) were female. Male to female ratio was 1.4:1. 5 (16.7%) of the IDMs were delivered vaginally while 25 (83.3%) were delivered by Caesarian Section (CS) where as 8 (38.1%) of the non- IDMs were delivered vaginally while 13 (61.9%) were delivered by CS. Respiratory distress was the most common morbidity affecting 70% of the IDMs and 66.7% of the non-IDMs. TTN accounted for the majority of the respiratory distress cases, occurring in 17 of the IDMs and 12 of the non-IDMs. Regarding analysis of other clinical features, convulsion (63.3%) was present more in IDMs than in non-IDMs (52.4%) cyanosis was found more in IDMs (60%) than non-IDMs (38.1%). Hypoglycemia was found more in IDMs than in non-IDMs. Mean glucose values were 41.06±19.91mg/dl for IDMs and 53.06±28.96mg/dl for the non-IDMs (p=0.001). Hyperbilirubinemia was more frequently observed in IDMs than in non- IDMs. About 17 (56.6%) of the IDMs and 7(33.3%) of the non-IDMs developed jaundice during the period of hospital stay. Polycythemia was not observed in both the groups but PCV was higher in IDMs (53.96±6.36) compared to non-IDMs (50.50±8.76). Hypocalcemia was not peculiar to a specific group. Five of the IDMs had congenital anomaly, of which three of them had cardiac anomaly. One of the non-IDM was suffering from ventricular septal defect. Birth asphyxia was observed more in non-IDMs (71.4%) than in IDMs (53.3%).One of the IDMs and two of the non-IDMs sustained a brachial plexus injury following vaginal delivery. On an average, IDMs had a longer duration of hospital stay. Outcome was more fatal in IDMs. About six (20%) of IDMs died compared to two (9.5%) of the non-IDMs. That was found statistically significant (p=<0.05).Conclusion: LGA babies with diabetic mother had more adverse outcome in terms of mortality and blood glucose level. More concentration is needed to control blood glucose of mother during pregnancy. Also extra care for the babies is needed to avoid fatal neonatal outcomes.Chatt Maa Shi Hosp Med Coll J; Vol.16 (2); July 2017; Page 25-30

Leptin, Insulin, and Glucose Serum Levels in Large-for-Gestational-Age Infants of Diabetic and Non-Diabetic Mothers

2008 ◽  
Vol 21 (1) ◽  
Author(s):  
M.M. Vela-Huerta ◽  
E.U. San Vicente-Santoscoy ◽  
J.M. Guizar-Mendoza ◽  
N. Amador-Lieona ◽  
C. Aldana-Valenzuela ◽  
...  
Keyword(s):  
Gestational Age ◽  
Serum Levels ◽  
Large For Gestational Age ◽  
Diabetic Mothers

Magnesium, Total Calcium, Phosphorus, Copper, and Zinc in Plasma and Erythrocytes of Venous Cord Blood from Infants of Diabetic Mothers: Comparison with a Reference Group by Logistic Discriminant Analysis

1992 ◽  
Vol 38 (10) ◽  
pp. 2002-2007 ◽  
Author(s):  
M Speich ◽  
A Murat ◽  
J L Auget ◽  
B Bousquet ◽  
P Arnaud
Keyword(s):  
Cord Blood ◽  
Gestational Age ◽  
Comparison Group ◽  
Reference Group ◽  
Total Calcium ◽  
Infants Of Diabetic Mothers ◽  
Calcium Phosphorus ◽  
The Mean ◽  
Diabetic Mothers ◽  
Apparently Healthy

Abstract Concentrations of magnesium (Mg), total calcium (Ca), phosphorus (P), copper (Cu), and zinc (Zn) were investigated in plasma (Pl) and erythrocytes (Erc) of venous cord blood of 44 infants of diabetic mothers (IDMs). These same concentrations plus total glycohemoglobin and fructosamine were determined at delivery in a subset of 15 mothers of these infants. Mineral results for IDMs were compared with those for 66 apparently healthy newborns. The duration of gestation in the two groups was significantly different (P &lt; 0.001). After adjustment for gestational age, the mean (+/- SD) differences between groups were significant for birth weight, head circumference, Erc-Mg (1.71 +/- 0.17 for IDMs vs 1.76 +/- 0.15 mmol/L for control subjects), Pl-Ca (1.96 +/- 0.32 vs 2.48 +/- 0.22 mmol/L), Pl-P (1.99 +/- 0.40 vs 1.57 +/- 0.25 mmol/L), and Erc-Cu (10.9 +/- 2.41 vs 12.9 +/- 3.00 mumol/L), but not for Erc-Zn (33.0 +/- 18.3 vs 40.4 +/- 13.6 mumol/L). The variable that best discriminated between the two infant groups after adjustment for gestational age was Pl-Ca. In the 15 mothers, Pl-Mg (0.67 +/- 0.07 mmol/L) and Pl-Ca (1.66 +/- 0.21 mmol/L) concentrations were low, Pl-Zn (9.81 +/- 3.40 mumol/L) was normal, and Pl-Cu (33.5 +/- 10.7 mumol/L) was above normal. Correlations between total glycohemoglobin and mineral values of the mothers or paired IDM mineral values were not significant. The concentration of Pl-Ca was positively correlated with Erc-Cu (P &lt; 0.001) and Pl-Cu (P &lt; 0.05) in the comparison group newborns but not in the IDMs.

ALPHA1-FETOPROTEIN AND CARBONIC ANHYDRASE B AND C CONCENTRATION IN CORD BLOOD FROM NEWBORN INFANTS OF DIABETIC MOTHERS

1974 ◽  
Vol 77 (3_Suppl) ◽  
pp. S81-S86 ◽  
Author(s):  
B. Nørgaard-Pedersen ◽  
J. G. Klebe
Keyword(s):  
Carbonic Anhydrase ◽  
Cord Blood ◽  
Gestational Age ◽  
Newborn Infants ◽  
Infants Of Diabetic Mothers ◽  
Carbonic Anhydrase B ◽  
Erythrocyte Carbonic Anhydrase ◽  
Diabetic Mothers

ABSTRACT Erythrocyte carbonic anhydrase (CA) concentration B and C and the α1-fetoprotein (AFP) concentration was determined in cord blood from 45 newborn infants of diabetic mothers (IDM). The concentration of these quantities has separately been compared with the corresponding concentration in cord blood from normal newborn infants with the same gestational age. No difference was found except for AFP, where a significantly (P < 0.05) higher concentration was found in some infants of insulin treated diabetic mothers.

Abstract 16893: Subclinical Decrease in Myocardial Function in Asymptomatic Infants of Diabetic Mothers: A Tissue Doppler Study

Circulation ◽  
2015 ◽  
Vol 132 (suppl_3) ◽  
Author(s):  
Jenny E Zablah ◽  
Dorota Gruber ◽  
Denise A Hayes
Keyword(s):  
Birth Weight ◽  
Cardiac Hypertrophy ◽  
Gestational Age ◽  
Myocardial Function ◽  
Ductus Arteriosus ◽  
Tissue Doppler ◽  
Doppler Imaging ◽  
Infants Of Diabetic Mothers ◽  
Ultrasound System ◽  
Diabetic Mothers

Introduction: Infants of diabetic mothers (IDMs) with cardiac hypertrophy are recognized to have impaired myocardial performance, but less is known about ventricular function in those without hypertrophy. We hypothesized that, in asymptomatic newborns with normal echocardiograms, tissue Doppler imaging (TDI) indices of cardiac function would be decreased in IDMs compared to controls. Methods: This retrospective case-control study involved IDMs ≥ 36 weeks gestational age, at 0 to 7 days of life. Subjects with cardiorespiratory symptoms, ventricular hypertrophy or dysfunction, or any echocardiographic abnormality (other than a patent ductus arteriosus before 4 days of life, or a patent foramen ovale) were excluded. Each subject was matched with 3 controls (healthy infants of non-diabetic mothers) by age (0-24, 25-48, 49-72, or > 72 hours of life), birth weight (± 0.5 kg), body surface area (± 0.03 m 2 ), and by the ultrasound system utilized. TDI systolic (S’), early diastolic (E’), and late diastolic (A’) velocities were measured at the mitral valve (MV) annulus, basal ventricular septum, and tricuspid valve (TV) annulus, and were averaged from 3 consecutive cardiac cycles. Early Doppler inflow velocity to E’ ratios (E/E’) were calculated. Results: Seventy cases (39 male) were identified: first 24 hours (h) of life (n=18), 25-48 h (n=22), 49-72 h (n=14), and > 72 h (n=16). Maternal diabetes was gestational in 60 cases, and pre-existing in 10. Median gestational age was 38 6/7 weeks (range 36-41 2/7), median birth weight 3.65 kg (2.56-5.38), and median BSA 0.22 m 2 (0.17-0.27). Ultrasound system vendors included Siemens ® (n=46), Philips ® (n=23), and General Electric ® (n=1). Cases were matched with 210 controls. IDMs had significantly lower S’ ( p ≤ 0.05) and E’ ( p ≤ 0.01) velocities, and significantly higher E/E’ ratios ( p ≤ 0.01) at the MV, basal septum, and TV compared to controls (Wilcoxon rank-sum test). There were no significant differences in A’ values between groups. Intraclass correlation demonstrated 84-99% interobserver and 98-99% intraobserver reliability. Conclusions: In asymptomatic newborn IDMs without cardiac hypertrophy, TDI suggests a subclinical decrease in systolic and diastolic myocardial function compared to controls.

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