Urethral involvement of myeloma: A rare case of visible haematuria leading to a diagnosis of relapsed multiple myeloma after curative stem cell transplantation

2015 ◽  
Vol 10 (3) ◽  
pp. 208-210
Author(s):  
C Patel ◽  
PP Irwin ◽  
D Dey
Keyword(s):  
Multiple Myeloma ◽  
Stem Cell ◽  
Unusual Case ◽  
Stem Cell Transplant ◽  
Autologous Stem Cell Transplant ◽  
Cell Transplant ◽  
Cell Infiltrate ◽  
First Case ◽  
Malignant Plasma Cell ◽  
Urethral Lesion

Extramedullary multiple myeloma involving the urinary tract is extremely rare. We report an unusual case of visible haematuria in a 45-year-old male who had a stem cell transplant for multiple myeloma 18 months previously. Cysto-urethroscopy revealed a mid-urethral lesion that was then fully excised by endoscopic resection. Histology confirmed malignant plasma cell infiltrate with subsequent staging and skeletal biopsy of a rib lesion confirming relapse of multiple myeloma. We believe this is the first case of urethral involvement to reveal a relapse of multiple myeloma after autologous stem cell transplant.

scholarly journals Multiple Myeloma in a Patient with ANKRD26-Related Thrombocytopenia Successfully Treated with Combination Therapy and Autologous Stem Cell Transplant

2019 ◽  
Vol 2019 ◽  
pp. 1-3
Author(s):  
Muhammad Husnain ◽  
Trent Wang ◽  
Maikel Valdes ◽  
James Hoffman ◽  
Lazaros Lekakis
Keyword(s):  
Multiple Myeloma ◽  
Stem Cell ◽  
Combination Therapy ◽  
Myeloid Leukemia ◽  
Stem Cell Transplant ◽  
Autologous Stem Cell Transplant ◽  
Cell Transplant ◽  
Normal Platelet ◽  
First Case ◽  
Repeat Domain

Ankyrin repeat domain-containing protein 26- (ANKRD26-) related thrombocytopenia is a rare, autosomal dominant condition caused by ANKRD26 gene mutation. ANKRD26-related thrombocytopenia is characterized by moderate thrombocytopenia with minimal bleeding, normal platelet size, and dysmegakaryopoiesis on bone marrow evaluation. ANKRD26 mutation has been previously associated with myeloid malignancies, including acute myeloid leukemia, myelodysplastic syndrome, and chronic myeloid leukemia. We report the first case of multiple myeloma in a patient with ANKRD26 related thrombocytopenia. The patient was successfully treated with contemporary combination therapy followed by melphalan-conditioned autologous stem cell transplant for his multiple myeloma despite preexisting thrombocytopenia.

scholarly journals Patient‐reported outcomes following autologous stem cell transplant for patients with multiple myeloma

eJHaem ◽  
2021 ◽  
Author(s):  
Noa Biran ◽  
Wanting Zhai ◽  
Roxanne E. Jensen ◽  
Jeanne Mandelblatt ◽  
Susan Kumka ◽  
...  
Keyword(s):  
Multiple Myeloma ◽  
Stem Cell ◽  
Patient Reported Outcomes ◽  
Stem Cell Transplant ◽  
Autologous Stem Cell Transplant ◽  
Cell Transplant ◽  
Patient Reported

Poster: MM-293: Early Relapse After Autologous Stem Cell Transplant in Multiple Myeloma: Single-Center Experience in Salamanca, Spain

2021 ◽  
Vol 21 ◽  
pp. S254
Author(s):  
Felipe Peña-Muñoz ◽  
Luz Román-Molano ◽  
Danylo Palomino-Mendoza ◽  
Alberto Hernández-Sánchez ◽  
Borja Puertas-Martínez ◽  
...  
Keyword(s):  
Multiple Myeloma ◽  
Stem Cell ◽  
Stem Cell Transplant ◽  
Autologous Stem Cell Transplant ◽  
Cell Transplant ◽  
Single Center ◽  
Early Relapse ◽  
Single Center Experience
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