scholarly journals Overlap of Psoriatic Arthritis and Dermatomyositis

2021 ◽  
Vol 9 ◽  
pp. 232470962110577
Author(s):  
Christopher Schreiber ◽  
Melanie Khamlong ◽  
Nadia Raza ◽  
Bao Quynh Huynh
Keyword(s):  
Diabetes Mellitus ◽  
Cardiovascular Disease ◽  
Liver Disease ◽  
Psoriatic Arthritis ◽  
Literature Review ◽  
Inflammatory Arthritis ◽  
Fatty Liver Disease ◽  
Inflammatory Myopathy ◽  
Nonalcoholic Fatty Liver ◽  
Pubmed Search

Psoriatic arthritis is an inflammatory arthritis, most commonly occurring several years after the onset of psoriasis. Psoriatic arthritis is associated with many comorbidities, including diabetes mellitus, nonalcoholic fatty liver disease, fibromyalgia, and cardiovascular disease. Dermatomyositis is an inflammatory myopathy primarily affecting the skin and muscles. As per literature review, cases of psoriasis and dermatomyositis have been reported. In most published cases, the courses of these diseases develop independently. This is the case of a 45-year-old woman initially diagnosed with psoriatic arthritis who developed concurrent dermatomyositis. The methods used were PubMed search and UpToDate search.

scholarly journals Nonalcoholic Fatty Liver Disease, Diabetes Mellitus and Cardiovascular Disease: Newer Data

2013 ◽  
Vol 2013 ◽  
pp. 1-8 ◽  
Author(s):  
A. N. Mavrogiannaki ◽  
I. N. Migdalis
Keyword(s):  
Diabetes Mellitus ◽  
Cardiovascular Disease ◽  
Liver Disease ◽  
Fatty Liver ◽  
Nonalcoholic Fatty Liver Disease ◽  
Fatty Liver Disease ◽  
Microvascular Complications ◽  
Response To Therapy ◽  
Nonalcoholic Fatty Liver

Nonalcoholic fatty liver disease (NAFLD) is the most common, chronic liver disease worldwide. Within this spectrum, steatosis alone is apparently benign, while nonalcoholic steatohepatitis may progress to cirrhosis and hepatocellular carcinoma. NAFLD is strongly associated with obesity, dyslipidemia, type 2 diabetes mellitus, and cardiovascular disease. The pathogenesis of hepatic steatosis is not clearly known, but its main characteristics are considered insulin resistance, mitochondrial dysfunction, increased free fatty acids reflux from adipose tissue to the liver, hepatocyte lipotoxicity, stimulation of chronic necroinflammation, and fibrogenic response. With recent advances in technology, advanced imaging techniques provide important information for diagnosis. There is a significant research effort in developing noninvasive monitoring of disease progression to fibrosis and response to therapy with potential novel biomarkers, in order to facilitate diagnosis for the detection of advanced cirrhosis and to minimize the need of liver biopsy. The identification of NAFLD should be sought as part of the routine assessment of type 2 diabetics, as sought the microvascular complications and cardiovascular disease, because it is essential for the early diagnosis and proper intervention. Diet, exercise training, and weight loss provide significant clinical benefits and must be considered of first line for treating NAFLD.

Metabolic markers of cardiovascular disease and type 2 diabetes mellitus in various clinical and morphological forms of nonalcoholic fatty liver disease in patients with abdominal obesity

2018 ◽  
Vol 4 (3) ◽  
pp. 1
Author(s):  
KsenyaKomshilova KsenyaKomshilova ◽  
NatalyaMazurina NatalyaMazurina ◽  
EkaterinaTrosina EkaterinaTrosina ◽  
TeonaShvangiradze TeonaShvangiradze ◽  
PavelBogomolov PavelBogomolov ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Cardiovascular Disease ◽  
Type 2 Diabetes Mellitus ◽  
Liver Disease ◽  
Fatty Liver ◽  
Fatty Liver Disease ◽  
Metabolic Markers ◽  
Nonalcoholic Fatty Liver
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