Onconephrology, an extra year of training: Where do we stand?

2020 ◽  
pp. 239936932097304
Author(s):  
Kenar D Jhaveri ◽  
Sonalika Agarwal
Keyword(s):  
Kidney Disease ◽  
Clinical Training ◽  
Next Generation ◽  
Specific Group ◽  
Close Collaboration ◽  
Cancer Centers ◽  
Pros And Cons ◽  
Local Expert ◽  
Second Year

Onconephrology is a new subspecialty of nephrology that recognizes the important intersections of kidney disease with cancer. As novel anti cancers are being used to treat patients, we are beginning to see even more kidney-related complications that require close collaboration with hematology and oncology colleagues. Secondary to the increased number and complexity of onconephrology consultations spanning nephrology and oncology, there is a need to expand and focus clinical training in this area. Some authors propose an extra year of fellowship in onconephrology and others propose against extra year of fellowship. An “area of concentration” during the second year of fellowship with 6–9 months of dedicated time might be a solution for a trainee interested in onconephrology. To train the next generation of fellows, all centers should consider at least a local expert in onconephrology and specialty clinics to teach the necessary skills. The large stand-alone cancer centers can then enhance those skills for a specific group of fellows interested by offering an extra year of fellowship. In this editorial, we discuss the pros and cons of having an extra year of training in onconephrology.

scholarly journals Approaches and Trends of Automatic Bangla Text Summarization

2020 ◽  
Vol 11 (4) ◽  
pp. 67-83
Author(s):  
Md. Majharul Haque ◽  
Suraiya Pervin ◽  
Anowar Hossain ◽  
Zerina Begum
Keyword(s):  
Research Work ◽  
Text Summarization ◽  
Internet User ◽  
English Text ◽  
The Internet ◽  
Next Generation ◽  
Huge Number ◽  
Pros And Cons ◽  
Review Study ◽  
Electronic Content

As long as the internet user is increasing, online electronic content is growing proportionally irrespective of languages. A lot of research works on English text summarization have come to light to deal with this gigantic body of online text. Unfortunately, a few works have been accomplished for Bangla though a huge number of people are involved with this language. This article has tried to explore the trend of research work on Bangla text summarization. Fourteen approaches have been briefly expounded here by addressing the pros and cons with some scope of improvement. A comparison has also been turned based on their incorporated features and evaluation results. It is expected that this article will draw the attention of more researchers in the area of Bangla text summarization and give a crystal-clear message about the opportunities to the next generation. The integrated message about all the existing methods has been depicted here to reveal the importance of Bangla text summarization. To the best of the author's knowledge, this is the first review study in this ground.

scholarly journals Clinical Trial Accrual Targeting Genomic Alterations After Next-Generation Sequencing at a Non-National Cancer Institute–Designated Cancer Program

2016 ◽  
Vol 12 (4) ◽  
pp. e396-e404 ◽  
Author(s):  
Kalyan C. Mantripragada ◽  
Adam J. Olszewski ◽  
Andrew Schumacher ◽  
Kimberly Perez ◽  
Ariel Birnbaum ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Clinical Trials ◽  
Next Generation Sequencing ◽  
National Cancer Institute ◽  
Next Generation ◽  
Genomic Alterations ◽  
Cancer Centers ◽  
Cancer Program ◽  
Clinical Trial Accrual ◽  
Generation Sequencing

Purpose: Successful clinical trial accrual targeting uncommon genomic alterations will require broad national participation from both National Cancer Institute (NCI)–designated comprehensive cancer centers and community cancer programs. This report describes the initial experience with clinical trial accrual after next-generation sequencing (NGS) from three affiliated non–NCI-designated cancer programs. Materials and Methods: Clinical trial participation was reviewed after enrollment of the first 200 patients undergoing comprehensive genomic profiling by NGS as part of an institutional intuitional review board–approved protocol at three affiliated hospitals in Rhode Island and was compared with published experience from NCI-designated cancer centers. Results: Patient characteristics included a median age of 64 years, a median of two lines of prior therapy, and a predominance of GI carcinomas (58%). One hundred sixty-four of 200 patients (82%) had adequate tumor for NGS, 95% had genomic alterations identified, and 100% had variants of unknown significance. Fifteen of 164 patients (9.2%) enrolled in genotype-directed clinical trials, and three patients (1.8%) received commercially available targeted agents off clinical trials. The reasons for nonreceipt of NGS-directed therapy were no locally available matching trial (48.6%), ineligibility (33.6%) because of comorbidities or interim clinical deterioration, physician's choice of a different therapy (6.8%), or stable disease (11%). Conclusion: This experience demonstrates that a program enrolling patients in specific targeted agent clinical trials after NGS can be implemented successfully outside of the NCI-designated cancer program network, with comparable accrual rates. This is important because targetable genes have rare mutation rates and clinical trial accrual after NGS is low.

scholarly journals Development of next generation sequencing panel for UMOD and association with kidney disease

PLoS ONE ◽  
2017 ◽  
Vol 12 (6) ◽  
pp. e0178321 ◽  
Author(s):  
Caitlin Bailie ◽  
Jill Kilner ◽  
Alexander P. Maxwell ◽  
Amy Jayne McKnight
Keyword(s):  
Next Generation Sequencing ◽  
Kidney Disease ◽  
Next Generation ◽  
Generation Sequencing

scholarly journals A Qualitative Exploration of Medical Student Empathy During the COVID-19 Pandemic

2021 ◽  
Author(s):  
Gabriel Ellison ◽  
Thomas Pruzinsky
Keyword(s):  
Medical Education ◽  
Medical Student ◽  
Medical Students ◽  
Clinical Training ◽  
Medical Specialty ◽  
Moral Dilemmas ◽  
Structured Interview ◽  
Family Responsibilities ◽  
Second Year ◽  
Difficult Times

Abstract BackgroundThere is evidence that medical student self-reported empathy may decline as one progresses through their clinical training. Due to the unprecedented changes to both patient care and medical education caused by COVID-19, it is reasonable to assume that medical student empathy may be impacted. The goal of this July 2020 study was to qualitatively explore how the COVID-19 pandemic might affect medical students’ reported experience of empathy.MethodUsing a semi-structured interview, the authors interviewed 12 medical students, 6 second-year and 6 fourth-year. They selected these groups because of the distinct differences in their clinical experience. ResultsData analysis identified 5 major themes: 1) Expanded Perspective (e.g., a feeling of “we’re in this together”, increased awareness of patient vulnerability) 2) Moral Dilemmas (e.g., difficult decisions faced by students as a result of the pandemic such as weighing educational vs. family responsibilities, students risking their own health to provide the best possible care) 3) Confirmation of Values (e.g., Feeling reaffirmed in decision to enter medicine, feeling the pandemic was “what we signed up for” by entering medical school) 4) Shaping Priorities (e.g., changes in medical specialty or populations of interest) 5) Barriers to Empathy and Adaptive Strategies (e.g., COVID-19 created many physical, psychological, and social barriers to empathy for students, students presented many strategies for ameliorating these barriers). Five students (42%) reported increased empathy with no students reporting a decrease in empathy due to experiences during the pandemic. Conclusions Participants did not report that their personal experience of empathy for patients was negatively influenced by the COVID-19 pandemic. Many reported that their empathy increased. The observed differences in responses by pre-clinical (second-year) and clinical (fourth-year) students suggests a possible shift in how empathy is experienced and practiced as one progresses through their medical education. The overwhelmingly positive responses to the semi-structured interview, emphasizing appreciation of the opportunity to discuss topics not previously openly discussed, underscores the importance of providing explicit opportunities for students to discuss their emotional/interpersonal experiences within medical education, particularly in difficult times such as the COVID-19 pandemic.

scholarly journals Biomarkers and Next Generation Sequencing in Chronic Kidney Disease

2016 ◽  
Vol 2 (1) ◽  
pp. 23-25
Author(s):  
Ying Shi ◽  
◽  
Hao Yi ◽  
Chunling Huang ◽  
Carol A. Pollock ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Next Generation Sequencing ◽  
Kidney Disease ◽  
Next Generation ◽  
Generation Sequencing

scholarly journals mGWAS: next generation genetic prediction in kidney disease

2020 ◽  
Vol 16 (5) ◽  
pp. 255-256
Author(s):  
Daniel Montemayor ◽  
Kumar Sharma
Keyword(s):  
Kidney Disease ◽  
Next Generation ◽  
Genetic Prediction

scholarly journals Imaging and Characterization of Extrasolar Planets with the Next Generation of Space Telescopes

Geosciences ◽  
2018 ◽  
Vol 8 (12) ◽  
pp. 442
Author(s):  
Ana I. Gómez de Castro
Keyword(s):  
Extrasolar Planets ◽  
Current Status ◽  
Next Generation ◽  
Special Issue ◽  
Space Telescopes ◽  
Large Space ◽  
Design Studies ◽  
Pros And Cons ◽  
Nm Range

The study and characterization of the exoplanets’ atmospheres and composition is in its infancy. The large facilities that will make feasible to image an exo-Earth are currently under study. This contribution to the special issue on “detection and characterization of extrasolar planets” is a summary on the current status of the design studies to build large space-based facilities working in the 100–3000 nm range for this purpose. The three basic designs: Fresnel imagers, starshades, and coronagraphs on large space telescopes are described. An outline of the pros and cons for each design is provided. The relevance of transmission spectroscopy to characterize exoplanets atmospheres is pointed out.

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