Impact of the 2004 mass drug administration for the control of lymphatic filariasis, in urban and rural areas of the Western province of Sri Lanka

2007 ◽  
Vol 101 (4) ◽  
pp. 335-341 ◽  
Author(s):  
G. S. A. Gunawardena ◽  
M. M. Ismail ◽  
M. H. Bradley ◽  
N. D. Karunaweera
2014 ◽  
Vol 8 (11) ◽  
pp. e3281 ◽  
Author(s):  
Ramakrishna U. Rao ◽  
Kumara C. Nagodavithana ◽  
Sandhya D. Samarasekera ◽  
Asha D. Wijegunawardana ◽  
Welmillage D. Y. Premakumara ◽  
...  

Author(s):  
Ginisha Gupta ◽  
Priyesh Marskole ◽  
Praveen Yuwane

Background: Currently 947 million people globally live in areas having endemic lymphatic filariasis and require preventive chemotherapy to stop the spread of infection. LF is transmitted by many mosquitoes particularly Culex and in some areas by Anopheles and Aedes too. This study was conducted to assess the programme implementation with respect to process and outcome indicators and to assess the reasons for non-compliance among population.Methods: We conducted a cross sectional study in Datia district, Madhya Pradesh during September 2014. We determined the sample size for survey based on standard guidelines for MDA coverage assessment. We identified four separate clusters, each with thirty households, for the survey. We selected three clusters from rural areas and one cluster from urban area to ensure adequate representation. We used stratified sampling technique for selection of three rural clusters.Results: We surveyed 859 study participants of Indergarh block, Datia district, residing in 120 households across four clusters. Among 859 study participants, the eligible population (excluding less than two year child and pregnant females) was 92% (790/859). District health authorities reported coverage of MDA across entire district to be 91%. We determined the distribution rate of DEC across all four clusters to be 84% (±9%). We identified highest drug distribution rate in Uchad (97%; 193/200) and lowest in Bargai (75%; 133/178).Conclusions: Non-compliant individuals are potential reservoir for the parasite which may serve as source of infection and transmission even after the mass drug administration ceases. As the prevalence of lymphatic filariasis continues to decrease with the implementation of control measures, addressing the issue of non-compliance holds primary importance to further substantiate the effect of our efforts. 


2019 ◽  
Vol 13 (4) ◽  
pp. e0007365 ◽  
Author(s):  
Ramakrishna U. Rao ◽  
Sandhya D. Samarasekera ◽  
Kumara C. Nagodavithana ◽  
Manjula W. Punchihewa ◽  
Udaya S. B. Ranasinghe ◽  
...  

2017 ◽  
Vol 11 (10) ◽  
pp. e0006066 ◽  
Author(s):  
Ramakrishna U. Rao ◽  
Sandhya D. Samarasekera ◽  
Kumara C. Nagodavithana ◽  
Tharanga D. M. Dassanayaka ◽  
Manjula W. Punchihewa ◽  
...  

2007 ◽  
Vol 6 (1) ◽  
pp. 11 ◽  
Author(s):  
Mirani V Weerasooriya ◽  
Channa T Yahathugoda ◽  
Darshana Wickramasinghe ◽  
Kithsiri N Gunawardena ◽  
Rohan A Dharmadasa ◽  
...  

2020 ◽  
Vol 20 (2) ◽  
pp. 167-174
Author(s):  
Ilo Dicko ◽  
Yaya Ibrahim Coulibaly ◽  
Modibo Sangaré ◽  
Bismark Sarfo ◽  
Priscillia Awo Nortey

Background: Lymphatic filariasis (LF) is a parasitic disease that has been targeted for elimination through the Mass Drug Administration (MDA.) Although the MDA started in the Ankobra community in Ghana in 2000, LF prevalence as reported in 2014 was relatively high (4.5%). Non-compliance to the MDA has been associated with the persistent LF prevalence in endemic regions. Objective: This study determined the factors associated with the non-compliance to the MDA among patients living in the Ankobra community, Ghana. Methods: A cross-sectional study using a one-stage cluster sampling method was used to collect data between June and July, 2017 in Ankobra. Questionnaires were used to collect data from health workers, the MDA drug distributors and study participants in Ankobra. Data analysis was performed using STATA 14. Logistic regression was used to measure the degree of association between the dependent (non-compliance) and independent variables. Non-compliance rate was defined as the percentage of individuals who self-reported that they did not actually swallow the drugs provided during the MDA. Results: The MDA coverage and non-compliance rates were 73.5% (147/200) and 33.33% (49/147) respectively. The main reason for non-compliance was fear of drug adverse events (75.51%, 37/49). Thought of “not being susceptible to LF” was significantly associated with the non-compliance (aOR= 2.83, [CI= 1.15, 6.98]). Conclusion: Health education about the susceptibility of residents getting LF disease in endemic community must be intensified to improve compliance to MDA medication ingestion and thus meet the Global Elimination of Lymphatic Filariasis by 2020.


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