"LEFT VENTRICULAR DIASTOLIC DYSFUNCTION IN IDIOPATHIC PULMONARY FIBROSIS: A TISSUE DOPPLER ECG STUDY". C.E. PAPADOPOULOS, G. PITSIOU, T.D. KARAMITSOS, H.I. KARVOUNIS, T. KONTAKIOTIS, G. GIANNAKOULAS, G.K. EFTHIMIADIS, P. ARGYROPOULOU, G.E. PARHARIDIS AND D. BOUROS. EUR RESPIR J 2008; 31: 701-706.

Introduction. Several cardiovascular manifestations in patients with diabetes may be asymptomatic. Left ventricular diastolic dysfunction (LVDD) is considered to be the earliest metabolic myocardial lesion in these patients, and can be diagnosed with tissue Doppler echocardiography. Silent myocardial ischemia (SMI) is a characteristic and frequently described form of ischemic heart disease in patients with diabetes. Objective. The aim of the study was to assess the prevalence of LVDD and SMI in patients with type 2 diabetes, as well as to compare demographic, clinical, and metabolic data among defined groups (patients with LVDD, patients with SMI and patients with type 2 diabetes, without LVDD and SMI). Methods. We investigated 104 type 2 diabetic patients (mean age 55.4?9.1 years, 64.4% males) with normal blood pressure, prehypertension and arterial hypertension stage I. Study design included basic laboratory assessment and cardiological workup (transthoracic echocardiography and tissue Doppler, as well as the exercise stress echocardiography). Results. LVDD was diagnosed in twelve patients (11.5%), while SMI was revealed in six patients (5.8%). Less patients with LVDD were using metformin, in comparison to other two groups (?2 =12.152; p=0.002). Values of HDL cholesterol (F=4.515; p=0.013) and apolipoprotein A1 (F=5.128; p= 0.008) were significantly higher in patients with LVDD. Conclusion. The study confirmed asymptomatic cardiovascular complications in 17.3% patients with type 2 diabetes.

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Left ventricular diastolic dysfunction by tissue Doppler echocardiography in pediatric chronic kidney disease

Pediatric Nephrology ◽

10.1007/s00467-013-2504-x ◽

2013 ◽

Vol 28 (10) ◽

pp. 2003-2013 ◽

Cited By ~ 21

Author(s):

Ylva Tranæus Lindblad ◽

Jonas Axelsson ◽

Rita Balzano ◽

Georgios Vavilis ◽

Milan Chromek ◽

...

Keyword(s):

Chronic Kidney Disease ◽

Kidney Disease ◽

Diastolic Dysfunction ◽

Doppler Echocardiography ◽

Tissue Doppler ◽

Left Ventricular Diastolic Dysfunction ◽

Left Ventricular ◽

Tissue Doppler Echocardiography ◽

Ventricular Diastolic Dysfunction

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Left ventricle diastolic dysfunction in diabetes: an update

Arquivos Brasileiros de Endocrinologia & Metabologia ◽

10.1590/s0004-27302007000200005 ◽

2007 ◽

Vol 51 (2) ◽

pp. 168-175 ◽

Cited By ~ 11

Author(s):

Cláudia Maria V. Freire ◽

Ana Luiza M.T. Moura ◽

Márcia de Melo Barbosa ◽

Lucas José de C. Machado ◽

Anelise Impeliziere Nogueira ◽

...

Keyword(s):

Diastolic Dysfunction ◽

Systolic Function ◽

Systolic Dysfunction ◽

Tissue Doppler ◽

Left Ventricular Diastolic Dysfunction ◽

Left Ventricular ◽

Diabetic Patients ◽

Detailed Evaluation ◽

Ventricular Diastolic Dysfunction ◽

And Function

Diabetes mellitus, a disease that has been reaching epidemic proportions, is an important risk factor to the development of cardiovascular complication. Diabetes causes changes within the cardiac structure and function, even in the absence of atherosclerotic disease. The left ventricular diastolic dysfunction (VE) represents the earliest pre-clinical manifestation of diabetic cardiomyopathy, preceding the systolic dysfunction and being able to evolve to symptomatic heart failure. The doppler echocardiography has emerged as an important noninvasive diagnostic tool, providing reliable data in the stages of diastolic function, as well as for systolic function. With the advent of recent echocardiographic techniques, such as tissue Doppler and color M-mode, the accuracy in identifying the moderate diastolic dysfunction, the pseudonormal pattern, has significantly improved. Due to cardiometabolic repercussions of DM, a detailed evaluation of cardiovascular function in diabetic patients is important, and some alterations may be seen even in patients with gestational diabetes.

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