scholarly journals Signs of oral dryness in relation to salivary flow rate, pH, buffering capacity and dry mouth complaints

2007 ◽  
Vol 7 (1) ◽  
Author(s):  
Najat MA Farsi
Keyword(s):  
Flow Rate ◽  
Salivary Flow ◽  
Buffering Capacity ◽  
Salivary Flow Rate ◽  
Dry Mouth ◽  
Ph Buffering ◽  
Oral Dryness ◽  
Ph Buffering Capacity

Salivary Flow Rate, pH, Buffering Capacity, Total Protein, Oxidative Stress and Antioxidant Capacity in Children with and without Dental Caries

2018 ◽  
Vol 42 (6) ◽  
pp. 445-449 ◽  
Author(s):  
Sudharani A Pyati ◽  
R Naveen Kumar ◽  
Vinod Kumar ◽  
N H Praveen Kumar ◽  
K M Parveen Reddy
Keyword(s):  
Antioxidant Capacity ◽  
Flow Rate ◽  
Total Protein ◽  
Chemical Properties ◽  
Salivary Flow ◽  
Buffering Capacity ◽  
Salivary Flow Rate ◽  
Ph Buffering ◽  
Total Antioxidant ◽  
Ph Buffering Capacity

Objectives: To measure and compare the levels of salivary flow rate, pH, buffering capacity, total protein, malondialdehyde (MDA) and total antioxidant capacity (TAC) between caries active and caries free children and to study the correlation between the DMFS/dfs score and above salivary parameters in caries active children. Study design: 50 caries active (DMFS/dfs ≥ 5) and 50 caries free (DMFS/dfs = 0) children aged between 6 to 12 years were included in the study. From all the children, unstimulated, mid-morning saliva samples were collected and salivary flow rate was calculated. Salivary pH, buffering capacity, total protein, MDA and TAC were measured. Results: The mean levels of salivary flow rate, pH, buffering capacity were significantly decreased (p < 0.05) and total protein, MDA and TAC were significantly increased (p < 0.05) in caries active children when compared to caries free controls. There was a proportionate decrease (p < 0.05) in salivary flow rate, pH and buffering capacity and proportionate increase (p > 0.05) in salivary total protein, MDA and TAC as DMFS/dfs score increased in caries active children. Conclusions: Significant alteration in the levels of salivary flow rate, pH, total proteins, MDA and TAC and their correlation with DMFS/dfs score in caries active children suggest, the levels of these physico-chemical properties of saliva can act as strong indicators of caries status in children.

scholarly journals Effect of a newly developed pastille on the salivary flow rate in subjects with dry mouth symptoms: a randomized, controlled, monocentric clinical study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
S. Bielfeldt ◽  
D. Wilhelm ◽  
C. Neumeister ◽  
U. Schwantes ◽  
K. -P. Wilhelm
Keyword(s):  
Surface Tension ◽  
Flow Rate ◽  
Gum Arabic ◽  
Salivary Flow ◽  
Salivary Flow Rate ◽  
Dry Mouth ◽  
Main Ingredient ◽  
Control Product ◽  
Swallowing Problems ◽  
The Mean

Abstract Background Xerostomia is associated with several diseases and is a side effect of certain drugs, resulting from reduced saliva secretion. Often, aged and sometimes younger people suffer from (idiopathic) xerostomia. Chewing gum and sucking pastilles may relieve symptoms of xerostomia by increasing the salivary flow rate due to the mechanical effect of sucking and gustatory stimulation. Swallowing problems and the urge to cough or experiencing a tickling sensation in the throat might be alleviated through a reduction in dry mouth symptoms. We investigated whether a pastille containing four polysaccharides increased the salivary flow rate and relieved the symptoms of dry mouth. Methods Participating subjects with xerostomia were randomized into two equally balanced treatment groups. Subjects received the pastille on Day 1 and a control product (Parafilm®) on Day 3, or vice versa. Unstimulated saliva was collected every 2.5 min for 0–10 min. Stimulated saliva was collected after subjects sucked the pastille or the control product. The salivary flow rate was determined gravimetrically, and, in parallel, the feeling of dry mouth was assessed using a visual analog scale. Saliva surface tension was measured in pooled saliva samples (0–5 min of sampling). Additionally, in stimulated saliva from six subjects who sucked the pastille, the presence of the main ingredient—gum arabic—was examined by Raman spectroscopy. Results Chewing the pastille significantly increased the mean salivary flow rate by 8.03 g/10 min compared to the mean changes after chewing the control product (+ 3.71 g/10 min; p < 0.0001). The mean score of dry mouth was significantly alleviated by the pastille (− 19.9 ± 17.9 mm) compared to the control product (− 3.3 ± 18.1 mm). No difference between the two products was seen regarding the saliva surface tension. Gum arabic was present in the saliva of all investigated subjects for up to 10 min after sucking the pastille. Conclusions The pastille was well tolerated and effective in increasing the salivary flow rate and reducing mouth dryness after sucking. These results were in line with the detection of the main ingredient, gum arabic, in saliva for up to 10 min after sucking the pastille. Trial registration German Register Clinical Trials (Deutsches Register Klinische Studien, DRKS) DRKS-ID: DRKS00017393, Registered 29 May 2019, https://www.drks.de/drks_web/navigate.do?navigationId=trial. HTML&TRIAL_ID = DRKS00017393.

Physiological Factors Affecting Salivary Flow Rate, Oral Sugar Clearance, and the Sensation of Dry Mouth in Man

1987 ◽  
Vol 66 (2_suppl) ◽  
pp. 648-653 ◽  
Author(s):  
C. Dawes
Keyword(s):  
Flow Rate ◽  
Salivary Flow ◽  
Salivary Flow Rate ◽  
Dry Mouth ◽  
Physiological Factors ◽  
Physiological Basis ◽  
Factors Affecting ◽  
Physiological Variables ◽  
Normal Ranges ◽  
Whole Saliva

This paper discusses methods for collection of both whole saliva and individual gland secretions, the normal ranges of salivary flow rate, the effects of physiological variables which influence flow rate, and the role of saliva in oral sugar clearance. The physiological basis for the sensation of dry mouth is discussed, and a new concept is advanced which states that the sensation of dry mouth will occur when the salivary flow rate is less than the sum of the rates of water absorption and evaporation from the mouth. In a study of the effects of anticholinergic agents on salivary flow, the subjects experienced the sensation of dry mouth when the normal flow rate of unstimulated saliva was reduced by from 40 to 50%.

scholarly journals Estimation of salivary pH, buffering capacity, flow rate, caries prevalence and oral manifestation in chronic renal failure patients undergoing dialysis

2020 ◽  
Vol 10 (2) ◽  
pp. 19-24
Author(s):  
Bidhata Ojha ◽  
Radha Baral ◽  
Dipshikha Bajracharya
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Flow Rate ◽  
Oral Hygiene ◽  
Buffering Capacity ◽  
Caries Prevalence ◽  
Oral Manifestation ◽  
Ph Buffering ◽  
Salivary Ph ◽  
Ph Buffering Capacity

Background: Renal failure is a process that expresses a loss of functional capacity of the nephrons, independently of its etiology. Although acute renal failure is reversible in the majority of cases, chronic renal failure presents a progressive course towards terminal renal failure. Hemodialysis is the most widely used technique leading to systemic alterations, oral complications and variations in the flow and composition of the saliva. The purpose of this study was to estimate salivary pH, buffering capacity, flow rate in chronic renal failure patients undergoing hemodialysis with its oral manifestation and caries prevalence. Methods: Saliva samples were collected from 40 patients with chronic renal failure undergoing dialysis and 40 healthy subjects after taking the informed consent. Saliva samples were then taken to the lab for processing. Salivary pH, buffering capacity and flow rate was estimated. DMFT was calculated. The statistical analysis was done using SPSS version 23. Results: A statistically significant rise in salivary pH, buffering capacity with decrease in flow rate was noted in chronic renal failure patients undergoing dialysis compared to controls. Furthermore, decrease in DMFT value was noted in CRF group despite of poor oral hygiene of the patient. We could also observe different oral manifestations in CRF group among which uremic fetor being the commonest. Conclusions: Our report suggest that saliva is noninvasive tool which act as an adjunct in diagnos­ing oral lesions and manifestations in CRF patients whose oral hygiene is often neglected with their reluctance in long term dental appointment in the middle of regular hemodialysis schedule.

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