Changes in Salivary Flow Rate and Buffering Capacity in Children with Newly Diagnosed Type 1 Diabetes Mellitus

2016 ◽  
Vol 22 (1) ◽  
pp. 48-54 ◽  
Author(s):  
Cüneyt Asım ARAL ◽  
Bilge Gülsüm NUR ◽  
Mustafa ALTUNSOY ◽  
Korcan DEMİR
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Type 1 Diabetes Mellitus ◽  
Flow Rate ◽  
Salivary Flow ◽  
Buffering Capacity ◽  
Salivary Flow Rate ◽  
Newly Diagnosed

scholarly journals Xerostomia appearance in type 1 diabetes mellitus children in RSUPN dr. Cipto Mangunkusumo Jakarta

2011 ◽  
Vol 23 (1) ◽  
Author(s):  
Adis Tyaning Puspitasari ◽  
Rosiliwati Wihardja ◽  
Jakobus Runkat
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Type 1 Diabetes Mellitus ◽  
Flow Rate ◽  
Salivary Flow ◽  
Diabetes Mellitus Type 1 ◽  
Salivary Flow Rate ◽  
Metabolic Disturbances ◽  
Oral Dryness

Diabetes mellitus is a chronic metabolic disease characterized by hyperglycemia due to insulin deficiency. As a result, there will be metabolic disturbances on carbohydrate, fat, and protein. Diabetes mellitus type 1 may occur because of pancreatic B cells damage resulting in decreased secretion of insulin in absolute terms. Xerostomia is the medical term for the subjective complaint of dry mouth due to the lack of saliva and can occur in patients with type 1 diabetes mellitus. The purpose of this study was to obtain data on the salivary flow rate and oral dryness complaints in children with type 1 diabetes mellitus The method of this study was descriptive by survey technique. The sample was obtained by purposive sampling and consisted of 30 children with type 1 diabetes mellitus in RSUPN Dr. Cipto Mangunkusumo Jakarta in April to May 2010. The study was conducted with an objective examination by measuring the salivary flow rate and subjective examination using a questionnaire. The results showed that the salivary flow rate from an average of 30 respondents was below normal values. The most common complaints about the dryness of the mouth cavity were thirst, 24 patients (80.00%), and oral dryness 19 patients (63.33%). The conclusion from this study showed that children with type 1 diabetes mellitus were having oral dryness complaints and the decrease of salivary flow rate.

Salivary flow rate, buffer capacity, and urea concentration in adolescents with type 1 diabetes mellitus

2016 ◽  
Vol 29 (12) ◽  
Author(s):  
Ivana Maria Saes Busato ◽  
Carlos Cesar De Antoni ◽  
Thiago Calcagnotto ◽  
Sérgio Aparecido Ignácio ◽  
Luciana Reis Azevedo-Alanis
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Type 1 Diabetes Mellitus ◽  
Flow Rate ◽  
Buffer Capacity ◽  
Salivary Flow ◽  
Urea Concentration ◽  
Type 1 Dm ◽  
Salivary Concentration

Abstract Background: The objective of the study was to analyze salivary flow rate, urea concentration, and buffer capacity in adolescents with type 1 diabetes mellitus (type 1 DM) in two different stages. Methods: This study was performed on adolescents (14–19 years), allocated between two groups: type 1 DM group comprised 32 adolescents with type 1 DM, and non-type 1 DM group comprised 32 nondiabetics. The adolescents in type 1 DM group were evaluated at a baseline (T0) and after 15 months (T1), and those in non-type 1 DM group were only evaluated at T0. Diabetic status was determined by glycosylated hemoglobin (GHb) and capillary glucose tests. Measurement of salivary flow was performed by means of stimulated saliva (SSFR) collection. The buffer capacity (BC) was determined, and analysis of urea salivary concentration was performed using the colorimetric method. Results: At T0, there were significant differences between diabetics and nondiabetics for SSFR and BC (p<0.05). In diabetics, SSFR was 0.790 mL/min in T0 and 0.881 mL/min in T1 (p>0.05). BC at T0 was 4.8, and at T1, it was 3.9 (p=0.000). Urea concentration mean value had a significant decrease at T1 (28.13) compared with T0 (34.88) (p=0.013). There was a negative correlation between SSFR and urea salivary concentration at both T0 (r=−0.426, p≤0.05) and T1 (r=−0.601, p≤0.01). Conclusions: In adolescents with type 1 DM, hyposalivation at T0 was associated with an increase in urea salivary concentration. At T1, hyposalivation was associated with a reduction in BC, and an increase in salivary urea.

scholarly journals The Influence of Type 1 Diabetes Mellitus on Dental Caries and Salivary Composition

2018 ◽  
Vol 2018 ◽  
pp. 1-7 ◽  
Author(s):  
Lulëjeta Ferizi ◽  
Fatmir Dragidella ◽  
Lidvana Spahiu ◽  
Agim Begzati ◽  
Vjosa Kotori
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Oral Health ◽  
Dental Caries ◽  
Type 1 Diabetes Mellitus ◽  
Flow Rate ◽  
Buffer Capacity ◽  
Salivary Flow ◽  
Control Group

Diabetes mellitus is the most common chronic disease that affects the oral health. The aim of the study is to evaluate the dental caries, salivary flow rate, buffer capacity, and Lactobacilli in saliva in children with type 1 diabetes mellitus compared to the control group.Methods.The sample consisted of 160 children of 10 to 15 years divided into two groups: 80 children with type 1 diabetes mellitus and 80 children as a control group. Dental caries was assessed using the DMFT index for permanent dentition. Stimulated saliva was collected among all children. Salivary flow rate and buffer capacity were measured, and the colonies ofLactobacillusin saliva were determined. The observed children have answered a number of questions related to their dental visits and parents’ education. The data obtained from each group were compared statistically using the chi-square test and Mann–WhitneyU-test. The significant level was set atp<0.05.Results. DMFT in children with type 1 diabetes was significantly higher than that in the control group (p<0.001). Diabetic children have a low level of stimulated salivary flow rate compared to control children (0.86 ± 0.16 and 1.10 ± 0.14). The buffer capacity showed statistically significant differences between children with type 1 diabetes and control group (p<0.001). Also, children with type 1 diabetes had a higher count and a higher risk ofLactobacilluscompared to the control group (p<0.05andp<0.001).Conclusion. The findings we obtained showed that type 1 diabetes mellitus has an important part in children’s oral health. It appears that children with type 1 diabetes are exposed to a higher risk for caries and oral health than nondiabetic children.

scholarly journals Serum vitamin D deficiency in children and adolescents is associated with type 1 diabetes mellitus

2018 ◽  
Vol 7 (12) ◽  
pp. 1275-1279 ◽  
Author(s):  
Changwei Liu ◽  
Jingwen Wang ◽  
Yuanyuan Wan ◽  
Xiaona Xia ◽  
Jian Pan ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Vitamin D ◽  
Type 1 Diabetes ◽  
Type 1 Diabetes Mellitus ◽  
Vitamin D Deficiency ◽  
Newly Diagnosed ◽  
25Ohd Level ◽  
Serum 25Ohd ◽  
The Mean

Background To investigate the relationship 25-hydroxy vitamin D (25OHD) level among children and in children with type 1 diabetes mellitus (T1DM). Methods A case–control study was conducted to compare the serum 25OHD levels between cases and controls. This study recruited 296 T1DM children (106 newly diagnosed T1DM patients and 190 established T1DM patients), and 295 age- and gender-matched healthy subjects as controls. Results The mean serum 25OHD in T1DM children was 48.69 ± 15.26 nmol/L and in the controls was 57.93 ± 19.03 nmol/L. The mean serum 25OHD in T1DM children was lower than that of controls (P < 0.01). The mean serum 25OHD level (50.42 ± 14.74 nmol/L) in the newly diagnosed T1DM children was higher than that (47.70 ± 15.50 nmol/L) in the established T1DM children but the difference was not statistically significant (P = 0.16). HbA1c values were associated with 25OHD levels in established T1DM children (r = 0.264, P < 0.01), and there was no association between 25OHD and HbA1c in newly diagnosed T1DM children (r = 0.164; P > 0.05). Conclusion Vitamin D deficiency is common in T1DM children, and it should be worthy of attention on the lack of vitamin D in established T1DM children.

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