scholarly journals Normal reference values for thoracic and abdominal aorta and main pulmonary artery dimensions by cardiovascular magnetic resonance: the Framingham heart study

2013 ◽  
Vol 15 (S1) ◽  
Author(s):  
Michael L Chuang ◽  
Philimon Gona ◽  
Carol J Salton ◽  
Connie W Tsao ◽  
Susan B Yeon ◽  
...  
Keyword(s):  
Cardiovascular Magnetic Resonance ◽  
Magnetic Resonance ◽  
Pulmonary Artery ◽  
Reference Values ◽  
Abdominal Aorta ◽  
Framingham Heart Study ◽  
Main Pulmonary Artery ◽  
Normal Reference ◽  
Heart Study ◽  
Thoracic And Abdominal

scholarly journals Reference values for left atrial size by cardiovascular magnetic resonance in the Framingham Heart Study Offspring cohort

2012 ◽  
Vol 14 (S1) ◽  
Author(s):  
Garima Arora ◽  
Philimon Gona ◽  
Carol J Salton ◽  
Susan J Blease ◽  
Christopher J O'Donnell ◽  
...  
Keyword(s):  
Cardiovascular Magnetic Resonance ◽  
Magnetic Resonance ◽  
Reference Values ◽  
Framingham Heart Study ◽  
Left Atrial ◽  
Offspring Cohort ◽  
Left Atrial Size ◽  
Heart Study ◽  
Atrial Size

scholarly journals Distribution, Determinants, and Normal Reference Values of Thoracic and Abdominal Aortic Diameters by Computed Tomography (from the Framingham Heart Study)

2013 ◽  
Vol 111 (10) ◽  
pp. 1510-1516 ◽  
Author(s):  
Ian S. Rogers ◽  
Joseph M. Massaro ◽  
Quynh A. Truong ◽  
Amir A. Mahabadi ◽  
Matthias F. Kriegel ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Reference Values ◽  
Framingham Heart Study ◽  
Normal Reference ◽  
Abdominal Aortic ◽  
Heart Study ◽  
Thoracic And Abdominal

Normal Reference Values and Reproducibility of Tricuspid Annulus Dimensions Using Cardiovascular Magnetic Resonance

2019 ◽  
Vol 124 (4) ◽  
pp. 594-598 ◽  
Author(s):  
Yang Zhan ◽  
Dany Debs ◽  
Mohammad A. Khan ◽  
Duc T. Nguyen ◽  
Edward A. Graviss ◽  
...  
Keyword(s):  
Cardiovascular Magnetic Resonance ◽  
Magnetic Resonance ◽  
Reference Values ◽  
Tricuspid Annulus ◽  
Normal Reference

scholarly journals Normal sex and age-specific parameters in a multi-ethnic population: a cardiovascular magnetic resonance study of the Canadian Alliance for Healthy Hearts and Minds cohort

2022 ◽  
Vol 24 (1) ◽  
Author(s):  
Judy M. Luu ◽  
Catherine Gebhard ◽  
Chinthanie Ramasundarahettige ◽  
Dipika Desai ◽  
Karleen Schulze ◽  
...  
Keyword(s):  
Cardiovascular Magnetic Resonance ◽  
Magnetic Resonance ◽  
Reference Values ◽  
Left Ventricular ◽  
Cardiovascular Magnetic Resonance Study ◽  
Ethnic Population ◽  
Clinical Trial Registration ◽  
Ventricular Ejection Fraction ◽  
Normal Reference ◽  
And Function

Abstract Background Despite the growing utility of cardiovascular magnetic resonance (CMR) for cardiac morphology and function, sex and age-specific normal reference values derived from large, multi-ethnic data sets are lacking. Furthermore, most available studies use a simplified tracing methodology. Using a large cohort of participants without history of cardiovascular disease (CVD) or risk factors from the Canadian Alliance for Healthy Heart and Minds, we sought to establish a robust set of reference values for ventricular and atrial parameters using an anatomically correct contouring method, and to determine the influence of age and sex on ventricular parameters. Methods and results Participants (n = 3206, 65% females; age 55.2 ± 8.4 years for females and 55.1 ± 8.8 years for men) underwent CMR using standard methods for quantitative measurements of cardiac parameters. Normal ventricular and atrial reference values are provided: (1) for males and females, (2) stratified by four age categories, and (3) for different races/ethnicities. Values are reported as absolute, indexed to body surface area, or height. Ventricular volumes and mass were significantly larger for males than females (p < 0.001). Ventricular ejection fraction was significantly diminished in males as compared to females (p < 0.001). Indexed left ventricular (LV) end-systolic, end-diastolic volumes, mass and right ventricular (RV) parameters significantly decreased as age increased for both sexes (p < 0.001). For females, but not men, mean LV and RVEF significantly increased with age (p < 0.001). Conclusion Using anatomically correct contouring methodology, we provide accurate sex and age-specific normal reference values for CMR parameters derived from the largest, multi-ethnic population free of CVD to date. Clinical trial registration ClinicalTrials.gov, NCT02220582. Registered 20 August 2014—Retrospectively registered, https://clinicaltrials.gov/ct2/show/NCT02220582.

Abstract 3117: Subclinical Aortic Atherosclerosis by Cardiovascular Magnetic Resonance Imaging Predicts Increased Cardiovascular Morbidity and Mortality in an Initially Healthy Cohort: The Framingham Heart Study

Circulation ◽  
2008 ◽  
Vol 118 (suppl_18) ◽  
Author(s):  
Michael L Chuang ◽  
Philimon Gona ◽  
Farouc A Jaffer ◽  
Carol J Salton ◽  
Kraig V Kissinger ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Cardiovascular Magnetic Resonance ◽  
Magnetic Resonance ◽  
Framingham Heart Study ◽  
Plaque Burden ◽  
Rank Test ◽  
Black Blood ◽  
Aortic Atherosclerosis ◽  
Heart Study ◽  
Cardiovascular Morbidity And Mortality

INTRODUCTION: We sought to determine whether subclinical aortic atherosclerosis, detected noninvasively using cardiovascular magnetic resonance (CMR), predicts major adverse cardiovascular events (MACE) in adults without history or clinical manifestation of cardiovascular disease (CVD). METHODS: 318 Framingham Heart Study (FHS) Offspring cohort members (60±9 yrs, 51% women) underwent CMR in 1998–1999. Subjects were free of clinical CVD and were recruited from equal strata of age, sex and quintile of Framingham Coronary Risk score (FCRS), with double sampling of the top quintile. CMR of the descending aorta on a 1.5-T system used an ECG-triggered black-blood T2W TSE sequence with 1.03 × 0.64 × 5-mm 3 voxels, 10-mm gap. Aortic-lumen and plaque areas were hand-traced. MACE included CV death, myocardial infarction (MI), stroke or new heart failure (HF). A Cox proportional hazards model adjusted for FCRS was used to determine hazard ratio (HR) for MACE for the (within-sexes) quartile of subjects with greatest plaque burden (Q4) vs other subjects (Q1–3). Log-rank test was used to compare survival. RESULTS: CMR aortic atherosclerosis was identified in 38% of women and 41% of men. Over median 5.2-yr follow up, 38 MACE (4 deaths, 14 MIs, 12 strokes, 8 HF) occurred among 31 subjects. Greater plaque burden (Q4) was associated with 2.75-fold greater hazard of MACE (95% CI 1.33 – 5.69, p=0.007). The Figure shows Kaplan-Meier survival, log-rank p=0.0009. CONCLUSIONS: In a free-living population without history of cardiovascular disease, CMR evidence of subclinical aortic atherosclerosis was a predictor of 5-year MACE, even after adjustment for traditional cardiovascular risk factors.

Abstract 3574: Unsuspected Left Ventricular Wall Motion Abnormalities Identified by Cardiovascular Magnetic Resonance in a Free-Living Population: Lessons from the Framingham Heart Study

Circulation ◽  
2007 ◽  
Vol 116 (suppl_16) ◽  
Author(s):  
Connie W Tsao ◽  
Philimon Gona ◽  
Carol J Salton ◽  
Peter G Danias ◽  
Susan Blease ◽  
...  
Keyword(s):  
Cardiovascular Magnetic Resonance ◽  
Magnetic Resonance ◽  
Framingham Heart Study ◽  
Wall Motion ◽  
Left Ventricular ◽  
Short Axis ◽  
Free Living ◽  
Heart Study ◽  
History Of ◽  
Wall Motion Abnormalities

INTRODUCTION: Resting left ventricular (LV) wall motion abnormalities (WMAs) are associated with significant morbidity and mortality. We hypothesized that unsuspected resting WMAs would be present in a healthy population and applied cardiovascular magnetic resonance (CMR) to characterize the prevalence of these in a free-living population. METHODS: 1794 subjects in the Framingham Heart Study Offspring Cohort (844M, 65±9 yrs) underwent cine CMR in short-axis, 2-ch, and 4-ch planes. Wall motion was scored using a standard 17-segment model with a 5-point scale. Global and regional (Ant, Sept, Inf, Lat) wall motion score indices (WMSI=wall motion score/# segments) were calculated with a WMSI>1 considered abnormal. LV ejection fraction (EF) and mass index (LVMI) were measured from the short axis stack. Adjudicated clinical events [CE; a history of coronary heart disease (CHD) or congestive heart failure (CHF)] were assessed. RESULTS: WMAs were present in 143 subjects. Compared to subjects with no prior CE, those with CE (n=157) had greater prevalence of WMA (Global, 34% vs 6%; Ant, 16% vs 2%; Sept, 18% vs 3%; Inf, 28% vs 4%; Lat, 27% vs 3%; all p<0.0001) and higher Framingham Risk Score (FRS) (11±3 vs 7±4, p<0.0001). In subjects with CE, WMA was associated with higher LVMI (70±14 g/m 2 vs 59±14 g/m 2 , p<0.0001) and lower EF (53±11% vs 69±6%, p<0.0001), but not age, blood pressure (BP), or FRS. Among 1637 subjects with no CE, 90 (5.5%) had a WMA. In these subjects, WMA was associated with greater age, BP, FRS, and LVMI, and lower EF (TABLE ). In the entire (n=1794) cohort, WMAs were more prevalent in men than in women (40% vs 19% with CE; 9% vs 3% without CE, respectively, both p<0.0001). CONCLUSIONS: In this closely followed free-living population, 5.5% of subjects have WMAs despite the absence of CE. WMAs were associated with other parameters of cardiovascular risk. The presence of WMAs among subjects without history of CHD or CHF may identify those at risk for adverse cardiovascular events.

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