scholarly journals Characterization of bone repair in rat femur after treatment with calcium phosphate cement and autogenous bone graft

2010 ◽  
Vol 6 (1) ◽  
Author(s):  
Edela Puricelli ◽  
Adriana Corsetti ◽  
Deise Ponzoni ◽  
Gustavo L. Martins ◽  
Mauro G. Leite ◽  
...  
2006 ◽  
Vol 21 (5) ◽  
pp. 341-347 ◽  
Author(s):  
José Carlos Garcia de Mendonça ◽  
Rafael De Rossi ◽  
Celso Massaschi Inouye ◽  
Diego Rodrigo Paulillo Bazan ◽  
João Carlos Castro Monteiro ◽  
...  

PURPOSE: Morphological study comparing castor oil polyurethane and autogenous bone graft to repair bone defect in zygomatic bone of rabbits. METHODS: Twenty-four adult, male New Zealand rabbits were randomly distributed between two groups of twelve. Bone defects of 5mm in diameter were cut through the zygomatic bone and filled with polyurethane discs in the experimental group or autogenous bone harvested from the tibia in the control group. Animals were sacrificed after 30, 60 or 90 days, and the zygomatic bones were macro- and microscopically analyzed. Student's, Fisher's, chi-squared and McNemar's tests were used for statistical analysis. RESULTS: Both the castor oil polyurethane and the autograft adapted well to the defect, with no need for fixation. Fibrous connective tissue encapsulated the polyurethane, but no inflammation or giant cell reaction was observed. Acidophilic and basophilic areas were observed inside the micropores of the polyurethane, suggesting cell nuclei. After 90 days, bone repair with a lamellar pattern of organization was observed in the control group. CONCLUSION: The castor oil polyurethane was biocompatible and did not cause inflammation. It may be considered an alternative to fill bone defects.


2007 ◽  
Vol 18 (2) ◽  
pp. 281-286 ◽  
Author(s):  
Rosane Vieira da Silva ◽  
Celso Aparecido Bertran ◽  
Elizabete Yoshie Kawachi ◽  
Jos?? Angelo Camilli

2007 ◽  
Vol 16 (4) ◽  
pp. 413-420 ◽  
Author(s):  
Celina A. Prata ◽  
Suzie A. Lacerda ◽  
Luiz Guilherme Brentegani

2020 ◽  
Vol 8 (15) ◽  
pp. 3038-3049 ◽  
Author(s):  
Weiwei Liang ◽  
Min Gao ◽  
Jingsheng Lou ◽  
Yunyang Bai ◽  
Jing Zhang ◽  
...  

Integrating multiple pro-osteogenic factors into bone graft substitutes is a practical and effective approach to improve bone repair efficacy.


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