Self-reported adverse reactions in 4337 healthcare workers immunizations against novel H1N1 influenza

This chapter describes various biological hazards and their impact on workers and others. A major focus of the chapter is biological hazards in healthcare and laboratory settings, including exposure to bloodborne pathogens and prevention of diseases related to them. Sections deal with sharps injuries, HIV/AIDS, hepatitis B virus, hepatitis C virus, tuberculosis, and other infectious diseases that can be acquired in the work environment via direct contact, droplet or airborne spread, or fecal-oral transmission. In addition, infectious agents spread by animal contact or arthropod vectors in a broad range of settings will be addressed. Newly emerging infectious or re-emerging infections, such as those due to H5N1 and novel H1N1 influenza, Middle Eastern respiratory syndrome (MERS), and Ebola Virus Disease (EVD) as well as agents associated with bioterrorism are discussed.

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Sequential Seasonal H1N1 Influenza Virus Infections Protect Ferrets against Novel 2009 H1N1 Influenza Virus

Journal of Virology ◽

10.1128/jvi.02257-12 ◽

2012 ◽

Vol 87 (3) ◽

pp. 1400-1410 ◽

Cited By ~ 45

Author(s):

Donald M. Carter ◽

Chalise E. Bloom ◽

Eduardo J. M. Nascimento ◽

Ernesto T. A. Marques ◽

Jodi K. Craigo ◽

...

Keyword(s):

Influenza Virus ◽

H1n1 Influenza ◽

Cross Reactivity ◽

Influenza Viruses ◽

The Novel ◽

Virus Infections ◽

H1n1 Influenza Virus ◽

Virus Shedding ◽

2009 H1n1 ◽

Novel H1n1 Influenza

ABSTRACTIndividuals <60 years of age had the lowest incidence of infection, with ∼25% of these people having preexisting, cross-reactive antibodies to novel 2009 H1N1 influenza. Many people >60 years old also had preexisting antibodies to novel H1N1. These observations are puzzling because the seasonal H1N1 viruses circulating during the last 60 years were not antigenically similar to novel H1N1. We therefore hypothesized that a sequence of exposures to antigenically different seasonal H1N1 viruses can elicit an antibody response that protects against novel 2009 H1N1. Ferrets were preinfected with seasonal H1N1 viruses and assessed for cross-reactive antibodies to novel H1N1. Serum from infected ferrets was assayed for cross-reactivity to both seasonal and novel 2009 H1N1 strains. These results were compared to those of ferrets that were sequentially infected with H1N1 viruses isolated prior to 1957 or more-recently isolated viruses. Following seroconversion, ferrets were challenged with novel H1N1 influenza virus and assessed for viral titers in the nasal wash, morbidity, and mortality. There was no hemagglutination inhibition (HAI) cross-reactivity in ferrets infected with any single seasonal H1N1 influenza viruses, with limited protection to challenge. However, sequential H1N1 influenza infections reduced the incidence of disease and elicited cross-reactive antibodies to novel H1N1 isolates. The amount and duration of virus shedding and the frequency of transmission following novel H1N1 challenge were reduced. Exposure to multiple seasonal H1N1 influenza viruses, and not to any single H1N1 influenza virus, elicits a breadth of antibodies that neutralize novel H1N1 even though the host was never exposed to the novel H1N1 influenza viruses.

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The novel H1N1 Influenza A global airline transmission and early warning without travel containments

Chinese Science Bulletin ◽

10.1007/s11434-010-3180-x ◽

2010 ◽

Vol 55 (26) ◽

pp. 3030-3036 ◽

Cited By ~ 17

Author(s):

ChaoYi Chang ◽

ChunXiang Cao ◽

Qiao Wang ◽

Yu Chen ◽

ZhiDong Cao ◽

...

Keyword(s):

Early Warning ◽

Influenza A ◽

H1n1 Influenza ◽

The Novel ◽

Novel H1n1 Influenza

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Time for T? Thoughts about the 2009 novel H1N1 influenza outbreak and the role of T cell epitopes in the next generation of influenza vaccines

Human Vaccines ◽

10.4161/hv.6.2.11333 ◽

2010 ◽

Vol 6 (2) ◽

pp. 157-163 ◽

Cited By ~ 3

Author(s):

Anne S. De Groot ◽

Elizabeth McClaine ◽

Lenny Moise ◽

William Martin

Keyword(s):

T Cell ◽

H1n1 Influenza ◽

Influenza Vaccines ◽

T Cell Epitopes ◽

Next Generation ◽

Influenza Outbreak ◽

Novel H1n1 Influenza

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Adverse Reactions of the Second Dose of the BNT162b2 mRNA COVID-19 Vaccine in Healthcare Workers in South Korea

Journal of Korean Medical Science ◽

10.3346/jkms.2021.36.e153 ◽

2021 ◽

Vol 36 (21) ◽

Author(s):

Yun Woo Lee ◽

So Yun Lim ◽

Ji-Hyang Lee ◽

Joon Seo Lim ◽

Miseo Kim ◽

...

Keyword(s):

South Korea ◽

Healthcare Workers ◽

Adverse Reactions

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Behaviours regarding preventive measures against pandemic H1N1 influenza among Italian healthcare workers, October 2009

Eurosurveillance ◽

10.2807/ese.14.49.19432-en ◽

2009 ◽

Vol 14 (49) ◽

Author(s):

G La Torre ◽

D Di Thiene ◽

C Cadeddu ◽

W Ricciardi ◽

A Boccia

Keyword(s):

Healthcare Workers ◽

Preventive Measures ◽

H1n1 Influenza ◽

The United States ◽

Pandemic H1n1 ◽

Online Questionnaire ◽

Pandemic H1n1 Influenza ◽

Region Of Residence ◽

Similar Survey ◽

Harvard School

A survey on attitudes and behaviours towards preventive measures against pandemic H1N1 influenza 2009 was carried out during the month of October 2009 in Italy through an online questionnaire adapted to the Italian situation from a similar survey of the Harvard School of Public Health in the United States (US). Results show that the intention to get vaccinated against pandemic H1N1 influenza 2009 is generally low and that there are differences in attitudes and behaviours towards preventive measures against pandemic H1N1 influenza 2009 between physicians and nurses, especially concerning vaccination. Differences relate also to sex, region of residence and marital status.

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