scholarly journals The influence of hepatitis C infection and interferon-α therapy on thyrotropin blocking and stimulating autoantibodies in Graves' ophthalmopathy: a case report

2009 ◽  
Vol 2 (1) ◽  
pp. 12 ◽  
Author(s):  
Huy A Tran ◽  
Glenn EM Reeves
Keyword(s):  
Case Report ◽  
Hepatitis C ◽  
Interferon Α ◽  
Hepatitis C Infection ◽  
Graves Ophthalmopathy

scholarly journals Case Report: Severe Interstitial Pneumonitis Secondary to Pegylated Interferon α-2b and Ribavirin Treatment of Hepatitis C Infection

2004 ◽  
Vol 49 (11-12) ◽  
pp. 1966-1970 ◽  
Author(s):  
Valentin Fuhrmann ◽  
Ludwig Kramer ◽  
Edith Bauer ◽  
Hermann Laferl ◽  
Gerhard Tucek ◽  
...  
Keyword(s):  
Case Report ◽  
Hepatitis C ◽  
Interstitial Pneumonitis ◽  
Pegylated Interferon ◽  
Interferon Α ◽  
Hepatitis C Infection

Mechanisms of Action of Ribavirin in Antiviral Therapies

2001 ◽  
Vol 12 (5) ◽  
pp. 261-272 ◽  
Author(s):  
Robert C Tam ◽  
Johnson YN Lau ◽  
Zhi Hong
Keyword(s):  
Hepatitis C ◽  
Viral Infections ◽  
Rna Virus ◽  
Lassa Fever ◽  
Biological Properties ◽  
Interferon Α ◽  
Hepatitis C Infection ◽  
Antiviral Activities ◽  
Syncytial Virus

Although ribavirin was originally synthesized over 30 years ago and has been used to treat viral infections as monotherapy (respiratory syncytial virus and Lassa fever virus) or with interferon-α (IFN-α) as combination therapy (hepatitis C virus), the precise mechanism of its therapeutic activities remains controversial. In this review we focus on two main biological properties of ribavirin: its indirect and direct antiviral activities (with particular emphasis on its efficacy against chronic hepatitis C infection). Each property could individually or collectively account for its clinical efficacy against viral infections. First, with emphasis on the evidence for indirect activities of ribavirin, we will review the clinical observations that suggest that the immunomodulatory properties of ribavirin can in part account for its antiviral activities in vivo. We will then describe the mode of ribavirin's direct antiviral activities. These direct activities can be ascribed to several possible mechanisms, including the recently described activity as an RNA mutagen, a property that may be important in driving a rapidly mutating RNA virus over the threshold to ‘error catastrophe′.

Interferon-α Therapy and Anti–Human Leukocyte Antigen Antibodies in Hepatitis C Virus–Positive Patient: Case Report

2007 ◽  
Vol 39 (6) ◽  
pp. 2040-2041 ◽  
Author(s):  
C. Cervelli ◽  
G. Fontecchio ◽  
M.A. Fioroni ◽  
R. Azzarone ◽  
C. Battistoni ◽  
...  
Keyword(s):  
Case Report ◽  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Human Leukocyte Antigen ◽  
Human Leukocyte ◽  
Positive Patient ◽  
Interferon Α ◽  
Patient Case ◽  
Leukocyte Antigen

170: Recurrent Oral Ulcers in a Patient with Hemochromatosis and Hepatitis C Infection: A Case Report

1996 ◽  
Vol 115 (2) ◽  
pp. P210-P210 ◽  
Author(s):  
Lenhanh P. Tran ◽  
Elizabeth A. Blair ◽  
Ziad E. Deeb ◽  
Ana A. Cardenas
Keyword(s):  
Case Report ◽  
Hepatitis C ◽  
Hepatitis C Infection ◽  
Oral Ulcers

scholarly journals Nonresponse to Interferon-α Based Treatment for Chronic Hepatitis C Infection Is Associated with Increased Hazard of Cirrhosis

PLoS ONE ◽  
2013 ◽  
Vol 8 (4) ◽  
pp. e61568 ◽  
Author(s):  
Myrna L. Cozen ◽  
James C. Ryan ◽  
Hui Shen ◽  
Robert Lerrigo ◽  
Russell M. Yee ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Hepatitis C ◽  
Chronic Hepatitis C ◽  
Interferon Α ◽  
Hepatitis C Infection
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