Comparative study of four immortalized human brain capillary endothelial cell lines, hCMEC/D3, hBMEC, TY10, and BB19, and optimization of culture conditions, for an in vitro blood–brain barrier model for drug permeability studies

Brain Capillary ◽

Drug Permeability ◽

Permeability Studies ◽

Evaluation of the immortalised mouse brain capillary endothelial cell line, b.End3, as an in vitro blood–brain barrier model for drug uptake and transport studies

Brain Research ◽

10.1016/s0006-8993(03)03443-7 ◽

2003 ◽

Vol 990 (1-2) ◽

pp. 95-112 ◽

Cited By ~ 162

Author(s):

Yadollah Omidi ◽

Lee Campbell ◽

Jaleh Barar ◽

David Connell ◽

Saeed Akhtar ◽

...

Keyword(s):

Endothelial Cell ◽

Drug Uptake ◽

Brain Capillary ◽

Transport Studies ◽

Barrier Model ◽

Uptake And Transport

Functional expression of a proton-coupled organic cation (H+/OC) antiporter in human brain capillary endothelial cell line hCMEC/D3, a human blood–brain barrier model

Fluids and Barriers of the CNS ◽

10.1186/2045-8118-10-8 ◽

2013 ◽

Vol 10 (1) ◽

pp. 8 ◽

Cited By ~ 38

Author(s):

Keita Shimomura ◽

Takashi Okura ◽

Sayaka Kato ◽

Pierre-Olivier Couraud ◽

Jean-Michel Schermann ◽

...

Keyword(s):

Endothelial Cell ◽

Human Brain ◽

Human Blood ◽

Organic Cation ◽

Functional Expression ◽

Brain Capillary ◽

Functional Expression of Organic Cation/carnitine Transporter 2 (OCTN2/SLC22A5) in Human Brain Capillary Endothelial Cell Line hCMEC/D3, a Human Blood-brain Barrier Model

Drug Metabolism and Pharmacokinetics ◽

10.2133/dmpk.dmpk-13-rg-058 ◽

2014 ◽

Vol 29 (1) ◽

pp. 69-74 ◽

Cited By ~ 19

Author(s):

Takashi Okura ◽

Sayaka Kato ◽

Yoshiharu Deguchi

Keyword(s):

Endothelial Cell ◽

Human Brain ◽

Organic Cation ◽

Functional Expression ◽

Brain Capillary ◽

Carnitine Transporter ◽

Culture of mouse brain capillary endothelial cell lines that express factor VIII, γ-glutamyl transpeptidase, and form junctional complexes in vitro

In Vitro Cellular & Developmental Biology ◽

10.1007/bf02623679 ◽

1987 ◽

Vol 23 (11) ◽

pp. 775-781 ◽

Cited By ~ 18

Author(s):

Boro Dropulić ◽

Colin L. Masters

Keyword(s):

Endothelial Cell ◽

Factor Viii ◽

Cell Lines ◽

Mouse Brain ◽

Brain Capillary ◽

Junctional Complexes ◽

Glutamyl Transpeptidase

Monocytes deliver bioactive nerve growth factor through a brain capillary endothelial cell-monolayer in vitro and counteract degeneration of cholinergic neurons

Brain Research ◽

10.1016/j.brainres.2009.11.062 ◽

2010 ◽

Vol 1312 ◽

pp. 108-119 ◽

Cited By ~ 16

Author(s):

Danny Böttger ◽

Celine Ullrich ◽

Christian Humpel

Keyword(s):

Endothelial Cell ◽

Nerve Growth Factor ◽

Growth Factor ◽

Cell Monolayer ◽

Cholinergic Neurons ◽

Endothelial Cell Monolayer ◽

Brain Capillary

Bilirubin Efflux By Brain Capillary Endothelial Cell Monolayers in Vitro: Role of P-Glycoprotein.

Pediatric Research ◽

10.1203/00006450-200410000-00063 ◽

2004 ◽

Vol 56 (4) ◽

pp. 673-673

Author(s):

Deryk Sequeira ◽

Monica J Daood ◽

Jon F Watchko ◽

Burhan Mahmood

Keyword(s):

Endothelial Cell ◽

Brain Capillary ◽

Cell Monolayers ◽

P Glycoprotein

Marked Differences in the Effect of Antiepileptic and Cytostatic Drugs on the Functionality of P-Glycoprotein in Human and Rat Brain Capillary Endothelial Cell Lines

Pharmaceutical Research ◽

10.1007/s11095-013-1264-4 ◽

2014 ◽

Vol 31 (6) ◽

pp. 1588-1604 ◽

Cited By ~ 15

Author(s):

Dana Alms ◽

Maren Fedrowitz ◽

Kerstin Römermann ◽

Andreas Noack ◽

Wolfgang Löscher

Keyword(s):

Endothelial Cell ◽

Rat Brain ◽

Cell Lines ◽

Cytostatic Drugs ◽

Brain Capillary ◽

P Glycoprotein

The Proteome of Brain Capillary Endothelial Cells: Toward a Molecular Characterization of an In Vitro Blood–Brain Barrier Model

Expression Profiling in Neuroscience - Neuromethods ◽

10.1007/978-1-61779-448-3_10 ◽

2011 ◽

pp. 161-179 ◽

Cited By ~ 2

Author(s):

Sophie Duban-Deweer ◽

Christophe Flahaut ◽

Yannis Karamanos

Keyword(s):

Endothelial Cells ◽

Molecular Characterization ◽

Blood Brain Barrier ◽

Brain Barrier ◽

Brain Capillary ◽

Capillary Endothelial Cells ◽

Characteristics of L-citrulline transport through blood-brain barrier in the brain capillary endothelial cell line (TR-BBB cells)

Journal of Biomedical Science ◽

10.1186/s12929-017-0336-x ◽

2017 ◽

Vol 24 (1) ◽

Cited By ~ 7

Author(s):

Kyeong-Eun Lee ◽

Young-Sook Kang

Keyword(s):

Endothelial Cell ◽

Cell Line ◽

Blood Brain Barrier ◽

Brain Barrier ◽

Brain Capillary ◽

Endothelial Cell Line ◽

Blood Brain ◽

The Brain

Effect of MK-801 and U83836E on a porcine brain capillary endothelial cell barrier during hypoxia

Neuroscience Letters ◽

10.1016/0304-3940(95)11584-j ◽

1995 ◽

Vol 191 (3) ◽

pp. 169-172 ◽

Cited By ~ 39

Author(s):

Helga Giese ◽

Katharina Mertsch ◽

Ingolf E. Blasig

Keyword(s):

Endothelial Cell ◽

Brain Capillary ◽

Mk 801 ◽

Porcine Brain