scholarly journals BRAIN DEATH IN A NEUROLOGIC INTENSIVE CARE UNIT IN TURKEY

2015 ◽  
Vol 3 (Suppl 1) ◽  
pp. A987
Author(s):  
Z Kurtpınar ◽  
T Akbaş ◽  
S Şenadım ◽  
E Çoban ◽  
V Özkubat ◽  
...  
Neurology ◽  
2003 ◽  
Vol 60 (5) ◽  
pp. 837-841 ◽  
Author(s):  
C. Commichau ◽  
N. Scarmeas ◽  
S. A. Mayer

2014 ◽  
Vol 4 (1) ◽  
pp. 45-50
Author(s):  
Hafize Oksuz ◽  
Mahmut Arslan ◽  
Gokce Gisi ◽  
Birsen Dogu ◽  
Mustafa Gokce ◽  
...  

2012 ◽  
Vol 63 (2) ◽  
pp. 129-134 ◽  
Author(s):  
Santanu Chakraborty ◽  
Sean P. Symons ◽  
Martin Chapman ◽  
Richard I. Aviv ◽  
Allan J. Fox

Purpose In the intensive care unit (ICU), prognosticating patients who are comatose or defining brain death can be challenging. Currently, the criteria for brain death are clinical supported by paraclinical tests. Noncontrast computed tomography (CT) shows diffuse loss of grey-white differentiation consistent with infarction. We hypothesize that the extent of hypodensity is predictive of poor neurologic outcome or brain death. Materials and Methods A total of 235 consecutive adult patients with cardiac arrest or with serious trauma admitted to ICU in 1 year were studied. Seventy met inclusion criteria. CT images were reviewed by multiple observers blinded to final outcome who assessed for loss of grey-white conspicuity. A modification of the validated Alberta Stroke Program Early CT Score (ASPECTS) was used to include non–middle cerebral artery territories. Primary outcome was death or functional disability at 3 months. Dichotomized CT scores were correlated with poor clinical status (Glasgow Coma Score < 5 and APACHE [Acute Physiology and Chronic Health Evaluation] score >19) and poor outcome (modified Rankin Scale >2). Results The CT score was ≤10 in 7 patients and >10 in 63 patients. The CT score value correlated with the severity of baseline clinical status on the Glasgow Coma Score ( r = 0.53, P < .01) and negatively with the APACHE-II score ( r = −0.27, P < .05). The CT score value negatively correlated with functional outcome ( r = −0.40, P < .01). All the patients with a CT score ≤10 died. The sensitivity of the CT score for functional outcome was 24%, and specificity was 100%. Agreement among observers for the CT score was good (Intraclass correlation coefficient = 0.77). Conclusion Diffuse loss of grey-white matter differentiation is subtle but specific for poor neurologic outcome, which may allow earlier prognostication of patients in whom clinical parameters are difficult to assess.


2012 ◽  
Vol 11s1 (2) ◽  
pp. 546-549 ◽  
Author(s):  
Bárbara Cristina de Aguiar Ernesto Virginio ◽  
Cristina Lavoyer Escudeiro

Author(s):  
Özlem Özkan Kuşcu ◽  
Meltem Aktay

Objective: Organ transplantation is important for patients with end-stage organ failure to survive. For this reason, detection of brain death cases and adequate number of donations are necessary. Methods: 31 cases diagnosed with brain death between 01.01.2018-01.01.2020 were evaluated retrospectively. Demographic characteristics, diagnoses causing brain death, time to detect brain death, additional tests applied for the diagnosis of brain death, time to diagnosis of brain death and cardiopulmonary arrest or donation, the proportion of families accepting organ donation, the proportion of donors, organ removed from donors the number and blood types of the cases were recorded Results: The number of cases diagnosed with brain death was 31, and the mean age of the cases was 46,71 (1-89) years. 71% (n=22) of the patients were admitted to the intensive care unit from the emergency department. The most common reason for admission to the intensive care unit 67.7% (n=21) was intracranial bleeding. While the family donation rate was 19% (n=5), three cases who accepted the donation could be donors. The mean age of the patients for whom organ donation was accepted was 35.80±11 years, while the mean age of the patients for whom organ donation was not accepted was 57.43±21.30 years (p=0.04). Conclusion: Due to the increasing number of end-stage organ failure patients awaiting transplantation, it is necessary to increase the number of cadaveric donors. Timely and sufficient detection of brain death cases, increasing the family donation rate and increasing the number of cadaveric donors will be contributed.


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