scholarly journals Correlation of serum homocysteine and previous history of gestational diabetes mellitus

Author(s):  
Sudabeh Alatab ◽  
Hossein Fakhrzadeh ◽  
Farshad Sharifi ◽  
Mojde Mirarefin ◽  
Zohreh Badamchizadeh ◽  
...  
Author(s):  
Nasloon Ali ◽  
Aysha S. Aldhaheri ◽  
Hessa H. Alneyadi ◽  
Maha H. Alazeezi ◽  
Sara S. Al Dhaheri ◽  
...  

Gestational diabetes mellitus (GDM) increases the risk of adverse pregnancy outcomes in any pregnancy and recurrence rates are high in future pregnancies. This study aims to investigate the effect of self-reported history of previous GDM on behaviors in a future pregnancy. This is an interim cross-sectional analysis of the pregnant women who participated in the Mutaba’ah Study between May 2017 and March 2020 in the United Arab Emirates. Participants completed a baseline self-administered questionnaire on sociodemographic and pregnancy-related information about the current pregnancy and previous pregnancies. Regression models assessed the relationships between self-reported history of GDM and pre-pregnancy and pregnancy behaviors in the current pregnancy. Out of 5738 pregnant parous women included in this analysis, nearly 30% (n = 1684) reported a history of GDM in a previous pregnancy. Women with a history of previous GDM were less likely to plan their current pregnancies (adjusted odds ratio (aOR): 0.84, 95% confidence interval (CI) 0.74–0.96) and more likely to be worried about childbirth (aOR: 1.18, 95% CI 1.03–1.36). They had shorter interpregnancy intervals between their previous child and current pregnancy (aOR: 0.88, 95% CI 0.82–0.94, per SD increase). There were no significant differences between women with and without a history of GDM in supplement use, sedentary behavior, or physical activity before and during this current pregnancy. Nearly a third of parous pregnant women in this population had a history of GDM in a previous pregnancy. Pregnant women with a previous history of GDM were similar to their counterparts with no history of GDM in the adopted pre-pregnancy and prenatal health behaviors. More intensive and long-term lifestyle counseling, possibly supported by e-health and social media materials, might be required to empower pregnant women with a history of GDM. This may assist in adopting and maintaining healthy prenatal behaviors early during the pregnancy or the preconception phase to minimize the risk of GDM recurrence and the consequential adverse maternal and infant health outcomes.


2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Barnabas Kahiira Natamba ◽  
Arthur Araali Namara ◽  
Moffat Joha Nyirenda

Abstract Background The burden, determinants and outcomes of gestational diabetes mellitus (GDM) in sub-Saharan Africa are not known. We summarized existing evidence on the prevalence, risk factors and complications of GDM in the region. Methods PubMed was searched from inception to January 31st 2019. Studies were included if carried out in any of the sub-Saharan Africa countries and were available as abstracts or full texts. Interventional studies and those only including qualitative data were excluded. We employed random effects modelling to estimate the pooled GDM prevalence and risk ratios (RRs) for risk factors and outcomes of GDM and their 95%CI. Results 283 papers were identified in the initial search, 33 of which met the inclusion criteria. Data on GDM burden suggest a pooled prevalence of 9% (95%CI, 7–12%). Family history of type 2 diabetes and previous history of GDM, macrosomia, stillbirth and abortion were important risk factors of GDM. In addition, being overweight or obese, over 25 years of age or hypertensive increased the risk of GDM. In terms of complications, GDM more than doubles the risk macrosomia (RR; 95%CI: 2.2; 1.1–4.4). Conclusions There is a high burden of gestational diabetes mellitus in sub-Saharan Africa, but more studies are needed to document locally important risk factors as well as maternal and offspring outcomes. Interventions to reduce obesity among older African women might lead to reduced risk of GDM in sub-Saharan Africa.


Diabetes Care ◽  
2007 ◽  
Vol 30 (2) ◽  
pp. 348-353 ◽  
Author(s):  
S. Lim ◽  
S. H. Choi ◽  
Y. J. Park ◽  
K. S. Park ◽  
H. K. Lee ◽  
...  

2018 ◽  
Vol 13 (3) ◽  
pp. 149-158 ◽  
Author(s):  
Rajat Das Gupta ◽  
Sabyasachi Gupta ◽  
Anupom Das ◽  
Tuhin Biswas ◽  
Mohammad Rifat Haider ◽  
...  

2019 ◽  
Vol 26 (06) ◽  
Author(s):  
AASMA NAZ QURESHI ◽  
IRFAN AHMED ◽  
ASHOK KUMAR LOHANO ◽  
FARAH AFROZ ◽  
DR.KHAWER HUSSSAIN

Objectives: The objective of this study is to determine the frequency of factors leading to gestational diabetes mellitus and fetomaternal outcomes. Setting: Department of Obstetrics and Gynaecology Unit-II at Liaquat University Hospital Hyderabad. Study Design:  Cross sectional study. Duration of Study: Six months (1st July 2017 to 31st December 2017). Subject and Methods: A total of 86 Women with GDM included in the study by identification of risk factors from history an examination. A sample of capillary blood was tested with glucometer for random blood sugar level. GDM was diagnosed 2 hours blood glucose more than 126 mg/dl.Women with GDM was evaluated and followed to see the maternal outcome i.e. preterm delivery, pre-eclampsia and operative delivery and fetal outcome i.e. congenital anomalies, live birth, still birth, early neonatal death and macrosomia. All the data was entered on a pre-designed proforma attached at the end of synopsis. Results: The average age of the women was 26.23±4.03 years.  Frequency of factors leading to gestational diabetes mellitus was previous history of previous GDM; 66.3%, Previous history of macrosomia54.7%, Polyhydramnios in current pregnancy 51.2%, macrosomia in current pregnancy 44.2%,  previous history of shoulder dystosia 41.9%, and women with BMI >25kg/m2was observed in 32.6% cases. GDM causes significant maternal and fetal complications including preeclampsia 51.2%, preterm 23.3%, and operative delivery 29.1% as well as fetal death was observed in 21(24.4%) in which 17.44% still birth (15/86) and 6.98 (6/86) were neonatal death. Conclusion: Gestational Diabetes Mellitus is associated with increased morbidity in mothers and fetus. Early detection and intervention is important because it improves pregnancy outcome.


2021 ◽  
Vol 2021 ◽  
pp. 1-6
Author(s):  
Muche Argaw ◽  
Yibeltal Mesfin ◽  
Shegaw Geze ◽  
Keyredin Nuriye ◽  
Bitew Tefera ◽  
...  

Introduction. Preterm premature rupture of membrane is the rupture of membrane before 37 weeks of gestational age. It complicates approximately 3 percent of pregnancies and leads to one-third of preterm births. It increases the risk of prematurity and leads to several other perinatal and neonatal complications, including the risk of fetal death. Although the prevalence and associated factors of preterm premature rupture of the membrane were well studied in high-income countries, there is a scarcity of evidence in Ethiopia, particularly in the study area. Method. A hospital-based cross-sectional study design was conducted from 1st June to 30th June 2021 in Wolkite comprehensive specialized hospital. One hundred ninety nine (199) pregnant women were included as study subjects using a systematic random sampling technique. Data were collected using a structured interviewer-administered questionnaire. It carried out descriptive statistical analysis and statistical tests like the odds ratio. Both bivariate and multivariate logistic regression analyses were conducted. Statistically, significant tests were declared at a level of p value < 0.05. Result. The magnitude of preterm premature rupture membrane is 6.6%. Having gestational diabetes mellitus ( AOR = 5.99 (95% CI: 1.01, 32.97) and previous history of abortion ( AOR = 5.31 (95% CI: 1.06, 26.69) were found to be significantly associated with preterm premature rupture of membrane. Conclusion. Having gestational diabetes mellitus and having a previous history of abortion were significantly associated with preterm premature rupture of membrane.


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