scholarly journals Baseline predictors of response and discontinuation of tumor necrosis factor-alpha blocking therapy in ankylosing spondylitis: a prospective longitudinal observational cohort study

2011 ◽  
Vol 13 (3) ◽  
pp. R94 ◽  
Author(s):  
Suzanne Arends ◽  
Elisabeth Brouwer ◽  
Eveline van der Veer ◽  
Henk Groen ◽  
Martha K Leijsma ◽  
...  
2013 ◽  
Vol 88 (6 suppl 1) ◽  
pp. 26-28 ◽  
Author(s):  
Guida Santos ◽  
Lourdes Emerenciano Sousa ◽  
Alexandre Miguel Bruno Lopes João

The paradoxical adverse effects of tumor necrosis factor-alpha (TNF-alpha) antagonists have been described frequently as a result of the widespread use of these drugs. Among the TNF-alpha blocking agents, few reports exist relating the use of adalimumab in cutaneous sarcoidosis, although all of them show good results. More recently, sarcoidosis onsets have been reported with various TNF-alpha inhibitors. The current case is, to our knowledge, the first to describe the exacerbation of cutaneous lesions of sarcoidosis treated with adalimumab.


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