scholarly journals A supernumerary muscle complicated axillary lymphadenectomy: case report

2009 ◽  
Vol 11 (S1) ◽  
Author(s):  
T Totlis ◽  
R Iosifidou ◽  
F Pavlidou ◽  
Ath Papanikolaou ◽  
K Natsis ◽  
...  

2021 ◽  
Author(s):  
Hongping Tang ◽  
Lihua Zhong ◽  
Hongbing Jiang ◽  
Gui’e Xie

Abstract Background: Secretory carcinoma of the breast is one of the rarest entities accounting for less than 0.15% of all infiltrating breast carcinomas. It has characteristic histopathological and molecular features and more favorable prognosis. In this case report, we describe a local advanced secretory carcinoma of the breast with chemo-resisted for neoadjuvant chemotherapy and unfavorable prognosis.Case Presentation: A hard, painless and palpably bossed mass about 12 cm in diameter occupied most of the left breast of a 39-year-old woman and fixation to the overlying skin. Breast ultrasonography and magnetic resonance imaging (MRI) scan gave the same grading as BI-RADS IV. A needle biopsy was performed and pathological diagnosis was secretory carcinoma. Neoadjuvant chemotherapy (NAC) was then performed, after which ultrasonography and MRI scan revealed the tumor was partial response for EC therapy while progressive disease after the DC therapy. The tumor showed chemo-resisted for neoadjuvant chemotherapy. Left breast mastectomy and axillary lymphadenectomy were subsequently performed. Tumor cells were triple-negative and positive for S-100 and periodic acid-Schiff (PAS) staining. Fluorescence in-situ hybridization (FISH) analysis indicated the fusion arrangement of ETV6-NTRK3 gene. The patient underwent multiple distant metastases in brain, and died of these metastases 19 months after initial diagnosis.Conclusion: Secretory carcinomas of breast have been described as a low-grade histologic subtype with a favorable prognosis. This case showed chemo-resisted for neoadjuvant chemotherapy, multiple distant metastases, and final an unfavorable prognosis. Further research is needed to better understanding of its behavior and treatment of this rare tumor.



Mastology ◽  
2020 ◽  
Vol 30 (Suppl 1) ◽  
Author(s):  
Vanessa Monteiro Sanvido ◽  
Mary Miyazawa Simomoto ◽  
Afonso Celso Pinto Nazário

Introduction: Mammographic screening is recommended yearly after the age of 40; however, many pregnant women are younger and should undergo the test. In these cases, anamnesis and clinical examination of the breasts are essential to detect any breast change. In case of clinical suspicion, it is recommended to undergo mammography with abdominal protection, and breast ultrasound is the examination of choice to assess the extension of the injury and guide the percutaneous biopsy. Breast surgery is safe, and can be performed in the three trimesters of pregnancy. It is important to emphasize the importance of the type of surgery according to gestational age. The reference axillary surgery during pregnancy is axillary lymphadenectomy. However, some articles present the safety of the sentinel lymph node biopsy. The use of technetium (Tc-99m) with lymphoscintigraphy is an acceptable technique, with fetal exposure to radiation inferior to the teratogenic limit of 50 mGv. Objective: To emphasize the importance of mammary propedeutics during pregnancy. Case report: 37 year-old patient, primiparous, of 34 weeks, referred a nodule in the right breast for 1 year. She denies having family history of carcinoma. At clinical examination, she presented with turgid breasts, absence of palpable nodules and negative axilla. Current mammography with presence of architectural distortion in the inferolateral quadrant of the right breast, and ultrasound with irregular and spiculated 2 cm nodule , both BIRADS category 5. Percutaneous biopsy showed invasive breast carcinoma of no special type, histological grade 2, and immunohistochemical with positive hormone receptors (estrogen and progesterone receptor with 90%), negative HER2 and Ki 67 of 20%> The conduct was conserving surgery (excision of the breast injury and radio-guided sentinel lymph node biopsy) on the 36th week of pregnancy. The intraoperative assessment of the sentinel lymph node showed presence of macrometastasis and, as a consequence of the exclusion of pregnancy in the ACOSOG Z0011 study, the patient was submitted to axillary lymphadenectomy. The definitive anatomopathological result was invasive breast carcinoma of no special type, histological grade 3, measuring 2.1 cm, and 1 lymph node compromised by macrometastasis of 15 dissected nodes (pT2 pN1a). The multidisciplinary team chose to wait for delivery, from 2 to 4 weeks, and a Cesarean section was performed after 40 weeks of pregnancy. The chemotherapy was scheduled to begin 4 weeks after delivery. The patient was referred to genetic counselling. Conclusions: The treatment of breast cancer during pregnancy is challenging for the multidisciplinary team, which must focus on maternal and fetal well-being. Therapy should be carried out similarly to non-pregnant patients, respecting the procedures that are allowed in each gestational trimester. It is important to mention how essential it is to not delay the treatment, in order to not compromise the patient’s prognosis.



2017 ◽  
Vol 66 ◽  
pp. S123
Author(s):  
Shweta Kumari ◽  
Puja Chauhan ◽  
Mahendra Kathole ◽  
Jyoti Arora ◽  
Vandana Mehta ◽  
...  


2000 ◽  
Vol 118 (2) ◽  
pp. 46-48 ◽  
Author(s):  
Luiz Henrique Gebrim ◽  
Júlio Roberto de Macedo Bernardes Júnior ◽  
Afonso Celso Pinto Nazário ◽  
Cláudio Kemp ◽  
Geraldo Rodrigues de Lima

CONTEXT: The malignant variety of the phyllodes tumor is rare. The occurrence of invasive lobular carcinoma within fibroadenoma is rare as well. DESIGN: Case report. CASE REPORT: A 58-year-old black female patient was referred to the Mastology unit of the Department of Gynecology, Federal University of São Paulo / Escola Paulista de Medicina, in February 1990, presenting an ulcerated tumor in the right breast with fast growth over the preceding six months. She was a virgin, with meno-pause at the age of 45 years and had not undergone hormone replacement treatment. The physical examination showed, in her right breast, an ulcerated tumor of 20 x 30 cm which was not adher-ent to the muscle level, multilobular and with fibroelastic consistency. The axillary lymph nodes were not palpable. The left breast showed a 2 x 3 cm painless, movable nodule, with well-defined edges, and fibroelastic consistency. We performed left-breast mammography, which showed several nodules with well-defined edges, the largest being 2 x 3 cm and exhibiting rough calcification and grouped microcalcifications within it. The patient underwent a frozen biopsy that showed a malignant variant of the phyllodes tumor in the right breast and fibroadenoma in the left one. After that, we performed a total mastectomy in the right breast and an excision biopsy in the left one. Paraffin study confirmed the frozen biopsy result from the right breast, yet we observed that in the interior of the fibroadenoma that was removed on the left, there was a focal area of invasive lobular carcinoma measuring 0.4 cm. The patient then underwent a modi-fied radical mastectomy with total axillary lymphadenectomy. None of the 21 dissected lymph nodes showed evidence of metastasis. In the follow-up, the patient evolved asymptomatically and with normal physical and laboratory examination results up to July 1997.



2017 ◽  
Vol 4 (r) ◽  
Author(s):  
Adil ARSALANE ◽  
Abdelfetah ZIDANE ◽  
Smail SAADI ◽  
Yassine MSOUGAR

Primary Sarcomas of the breast account for less than 1% of breast tumors. Leiomyosarcomas are less common. Only 51 cases have been reported in the literature, which only 4 cases in men. We present a new case of male breast leiomyosarcoma and discuss management and therapy of these unusual neoplasms. The confirmation of diagnosis was obtained by immunohistochemical study of surgical biopsy. The patient underwent a radical mastectomy and axillary lymphadenectomy. Adjuvant radiotherapy was indicated. Two years after surgery the patient is still in life without recurrence.



2016 ◽  
Vol 5 (3) ◽  
pp. 169
Author(s):  
Rituparna Basu ◽  
Karabi Baral ◽  
Jayanta Sarkar ◽  
Koushik Ray ◽  
Bileswar Mistry


2013 ◽  
Vol 03 (01) ◽  
pp. 66-68
Author(s):  
Vishal K. ◽  
Kavitha K. ◽  
Vinay K. V. ◽  
Raghavendra A. Y.

AbstractThe Rectus Sternalis muscle is a small supernumerary muscle occasionally present in the anterior thoracic wall. During routine dissection for undergraduate medical students we observed a unilateral left sided rectus sternalis present on the anterior thoracic wall.The knowledge about this variation is very useful for morphologists and anatomists. The presence of this muscle may be mistaken by surgeons, radiologists and physicians for tumor on mammogram or during mastectomy which may increase unnecessary burden on their patients.



Mastology ◽  
2020 ◽  
Vol 30 (Suppl 1) ◽  
Author(s):  
Ridania de Oliveira Frederice

Introduction: It is estimated that 6% of the women with breast cancer (BC) present metastasis at diagnosis. In this context, the bone is the main site, followed by lung, liver and central nervous system. IN 15% of them, the bone presents as a single metastasis site, especially in the axial skeleton; unfrequently in the pelvis, and rarely in the appendicular skeleton. Case Report: In 2009, a female, 53-year old patient, in the menopause, hypertensive and former smoker, without family history of cancer, presented a palpable nodule in the right breast. At a consultation in the social responsibility service of Hospital Sírio Libanês, she presented a fragment biopsy compatible with invasive breast SOE, GH2, GN3, RE 80%, RP 50% and Ki67 20%. Staging was cT2 cN3C cM0. She underwent neoadjuvant chemotherapy with 4 cycles of doxorubicin with cyclophosphamide, and 12 of paclitaxel. She underwent quadrantectomy in the right breast, ipsilateral axillary lymphadenectomy, and reconstruction with thoracodorsal flap in August, 2010. Anatomopathological pT2pN3. She underwent radiotherapy of the breast and drainage, including supraclavicular fossa (50Gy) and boos (10Gy) until October, 2010. She used adjuvant anastrozole. In March, 2016, she reports pain and sudden loss of strength in the right forearm. X-ray and tomography showed extensive lesion in the radius, associated with pathological fracture without joint impairment. Systemic staging without other disease sites. Even though it was not possible to perform the biopsy, after a solid radiological evaluation, a secondary lesion was considered. She was started on exemestane and zoledronic acid, associated with immobilization and palliative radiotherapy (30Gy). The patient was asymptomatic, presented with pulmonary and lymph node progression in January, 201, changing from endocrine therapy to tamoxifen. In December, 2019, she started with fulvestrant de to discreet lymph node progression. She has been followed-up by an oncologist. Discussion: Lately, with advances in the multimodal treatment of BC, the global survival (GS) of the disease in stage IV has been increasing. Patients with single bone metastasis (SBM) have better prognosis, being mostly luminal tumors treated with the change of endocrine therapy. The main site of implantation is the lumbar and thoracic spine, and very rarely, the radius. Lee et al. reported, among 146 patients with bone metastasis, that 26 were in the femur; 5, in the humerus, and none in the radius, with progression-free survival of 24 months, and GS of 79 months. BC metastasis with appendicular skeleton, especially in the radius, are very rare; however, when SBM, present with better prognosis.



2020 ◽  
Vol 29 (4) ◽  
pp. 685-690
Author(s):  
C. S. Vanaja ◽  
Miriam Soni Abigail

Purpose Misophonia is a sound tolerance disorder condition in certain sounds that trigger intense emotional or physiological responses. While some persons may experience misophonia, a few patients suffer from misophonia. However, there is a dearth of literature on audiological assessment and management of persons with misophonia. The purpose of this report is to discuss the assessment of misophonia and highlight the management option that helped a patient with misophonia. Method A case study of a 26-year-old woman with the complaint of decreased tolerance to specific sounds affecting quality of life is reported. Audiological assessment differentiated misophonia from hyperacusis. Management included retraining counseling as well as desensitization and habituation therapy based on the principles described by P. J. Jastreboff and Jastreboff (2014). A misophonia questionnaire was administered at regular intervals to monitor the effectiveness of therapy. Results A detailed case history and audiological evaluations including pure-tone audiogram and Johnson Hyperacusis Index revealed the presence of misophonia. The patient benefitted from intervention, and the scores of the misophonia questionnaire indicated a decrease in the severity of the problem. Conclusions It is important to differentially diagnose misophonia and hyperacusis in persons with sound tolerance disorders. Retraining counseling as well as desensitization and habituation therapy can help patients who suffer from misophonia.



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