scholarly journals Yolk sac tumor in intraabdominal undescended testis in a child with normal serum alpha-fetoprotein: a rare case report

2020 ◽  
Vol 26 (1) ◽  
Author(s):  
Archika Gupta ◽  
Shiv Narain Kureel ◽  
Shalini Bhalla ◽  
Anand Pandey ◽  
Gurmeet Singh ◽  
...  
Keyword(s):  
Abdominal Mass ◽  
Testicular Tumor ◽  
Normal Serum ◽  
Yolk Sac ◽  
Alpha Fetoprotein ◽  
Yolk Sac Tumor ◽  
First Case ◽  
Preoperative Serum ◽  
Serum Alpha Fetoprotein ◽  
Cect Scan

Abstract Background Intraabdominal testicular tumors are rare in prepubertal children, and most of the cases reported are intraabdominal testicular teratoma. The present study reports the first case of intraabdominal testicular yolk sac tumor (YST) with normal preoperative serum alpha-fetoprotein levels and diagnosis confirmed on histopathology and immunohistochemistry. Case Presentation A 2-year-old boy presented with bilateral nonpalpable undescended testes (UDT) and abdominal mass. Preoperative serum alpha-fetoprotein was normal. Contrast-enhanced computed tomography (CECT) scan of whole abdomen revealed a heterogeneous mildly enhancing space-occupying lesion in midline and left side of pelvis, left intraabdominal testis and nonvisualization of right testis. During surgery, the mass was found to involve right testis with one turn of torsion of its pedicle. Derotation of testis was performed, and right radical orchiectomy was performed. Left orchiopexy was also performed at the same time. Histopathology and immunohistochemistry confirmed diagnosis of intraabdominal testicular YST. There was no recurrence or distant metastasis at 12-month follow-up after surgery. Conclusion In a case of nonpalpable UDT and abdominal mass/pain, one should always consider possibility of intraabdominal testicular tumor and should investigate the case with serum tumor markers and ultrasound/CECT abdomen. Further, histology of tumor helps in guiding treatment of condition.

scholarly journals Pure yolk sac tumor of testis with lung metastasis in an adult patient - case report

2020 ◽  
Author(s):  
Pushpanjali Behera ◽  
Arvind Ahuja ◽  
Minakshi Bhardwaj
Keyword(s):  
Case Report ◽  
Lung Metastasis ◽  
Testicular Tumor ◽  
Yolk Sac ◽  
Cell Tumor ◽  
Yolk Sac Tumor ◽  
Patient Case ◽  
Mixed Germ Cell Tumor ◽  
Yolk Sac Tumors ◽  
Tumor In Childhood

Pure yolk sac tumor is the most frequently seen testicular tumor in childhood; however it is usually a component of mixed germ cell tumor in adults. Pure yolk sac tumors are quite rare in adults. Pure yolk sac tumor in adults has been categorized as yolk sac tumor, post-pubertal type. We report a case of pure yolk sac tumor of right testis with lung metastasis in a 37-year-old man who was successfully treated by high inguinal orchidectomy and BEP combination chemotherapy.    

scholarly journals A Case Report of Yolk Sac Tumor in Cerebellar Hemisphere and Review of Literature

2020 ◽  
Author(s):  
Yuting Zhang ◽  
Lusheng Li ◽  
Ling He
Keyword(s):  
Case Report ◽  
Histopathological Examination ◽  
Case Reports ◽  
Yolk Sac ◽  
Alpha Fetoprotein ◽  
Yolk Sac Tumor ◽  
Cerebellar Hemisphere ◽  
Review Of Literature ◽  
Intracranial Germ Cell Tumor ◽  
The Right

Abstract Background: Yolk sac tumor also known as endodermal sinus tumor, is a rare intracranial germ cell tumor. We reported a case of yolk sac tumor in cerebellar hemisphere, and reviewed associated literatures. The majority of tumor locations are near the midline. On review of literature, very few case reports of intracranial yolk sac tumor have been published, and there is only one case report has described a yolk sac tumor arising from the cerebellum. Case presentation: A two years old boy admitted to our hospital due to headache and unsteady gait for six days. CT and MRI demonstrated a tumor in the right cerebellar hemisphere, and the blood and cerebrospinal fluid alpha-fetoprotein were found increased. It was diagnosed as yolk sac tumor after operation comfirmed by histopathological examination. Postoperative chemotherapy was performed, and the patient suffered no tumor recurrence one year and a half after the surgery. Conclusions: The clinical characteristics and imaging diagnosis of intracranial yolk sac tumor are lack of specificity, the comfirmed diagnosis is depending on the combination of elevated alpha-fetoprotein and histopathological examination.

scholarly journals SEMINOMA ANAPLASTIK DENGAN YOLK SAC TUMOR TESTIS (MIXED GERM CELL TUMOR TESTIS)

2013 ◽  
Vol 4 (3) ◽  
Author(s):  
Lily Loho
Keyword(s):  
Germ Cell ◽  
Germ Cell Tumor ◽  
Chorionic Gonadotropin ◽  
Human Chorionic Gonadotropin ◽  
Testicular Tumor ◽  
Yolk Sac ◽  
Cell Tumor ◽  
Yolk Sac Tumor ◽  
Mixed Germ Cell Tumor ◽  
Β Hcg

Abstract: Testicular cancer is relatively rare, accounting for less than 1% of malignant tumors affecting men. More than 90% of these tumors are of germ cell origin and most of them are found in young men between the ages of 15-34 years. Germ cell tumors are divided into seminoma and nonseminoma tumors. The seminoma makes up 30-40% of all testicular tumors. An anaplastic seminoma is a classic type of seminoma that has three or more mitosis under the high power microscopic field, combined with other morphologic criteria such as nuclear hyperchromasia, greater nucleolar sizes, pleomorphism, and an amount of necrosis. We reported a case of a 38-year-old male that was clinically diagnosed with a left testicular tumor and with an elevated alpha fetoprotein (AFP) and β human chorionic gonadotropin (β HCG) serum. The histopathological diagnosis was an anaplastic seminoma with a yolk sac tumor (YCT), i.e. a mixed germ cell tumor. Keywords: seminoma, testicular tumor, yolk sac tumor.   Abstrak: Kanker testis relatif jarang,  <1% dari semua kanker ganas pada laki-laki. Lebih dari 90 persen jenis tumor ini berasal dari sel germinal dan umumnya menyerang laki-laki muda berusia 15-34 tahun. Tumor sel germinal dibagi atas dua jenis: seminoma dan non seminoma. Jenis seminoma terdapat pada 30-40% dari seluruh tumor testis. Seminoma anaplastik adalah seminoma dengan ciri klasik mikroskopik berupa adanya tiga atau lebih sel-sel mitosis per lapangan pandang besar, disertai terdapatnya kriteria morfologik lain seperti inti sel hiperkromatik, anak inti berukuran besar, pleomorfik, dan terdapatnya sejumlah nekrosis. Kami melaporkan kasus seorang laki-laki berusia 38 tahun dengan diagnosis klinis tumor testis kiri disertai peningkatan kadar alfa feto protein (AFP) dan β human chorionic gonadotropin (β HCG) serum. Diagnosis histopatologik ialah  seminoma anaplastik dengan tumor yolk sac (YCT), yaitu tumor sel germinal campuran. Kata kunci: seminoma, tumor testis, tumor yolk sac.

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