scholarly journals First case of periprosthetic joint infection due to Clostridioides difficile in China

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Yang Song ◽  
Hong Yi Shao ◽  
Xiang Cheng ◽  
Yu Guo
Keyword(s):  
Hip Joint ◽  
Periprosthetic Joint Infection ◽  
Joint Infection ◽  
Sample Collection ◽  
Movement Restriction ◽  
Clostridioides Difficile ◽  
First Case ◽  
Intestinal Infections ◽  
One Year ◽  
The Right

Abstract Background Clostridioides difficile usually causes intestinal infections. However, a 75-year-old lady had a periprosthetic joint infection due to this microorganism. We report a C. difficile infection of a prosthetic hip joint. Such an infection is rarely reported around the world. Case presentation The elder female patient presented with a 2-year history of right hip pain with movement restriction. Her right leg was shorter than another. The skin around the right hip joint was red and swollen without sinus. Her lab test result showed elevator ESR and CRP. Her X-ray film showed a massive bone defect. The patient had a total hip arthroplasty 16 years ago and had a revision 5 years ago. During this hospitalization, her cultures of the synovial fluid and tissue repeatedly grew C. difficile. She improved following two-stage revision surgery and antibiotic treatment. The patient has no recurrence of infection after a one-year follow-up. Conclusion A rapid and accurate sample collection is significant for culture results, making an outstanding contribution to the successful treatment.

scholarly journals First Case Report of a Late Onset Knee Periprosthetic Joint Infection Caused byLactococcus garvieae

2016 ◽  
Vol 2016 ◽  
pp. 1-3 ◽  
Author(s):  
V.-I. Neagoe ◽  
S. Zytoun ◽  
H.-J. Neuhaus
Keyword(s):  
Periprosthetic Joint Infection ◽  
Late Onset ◽  
Joint Infection ◽  
Hepatic Abscess ◽  
Nile Perch ◽  
Replacement Surgery ◽  
Source Of Infection ◽  
First Case ◽  
Contaminated Food ◽  
The Right

Lactococcus garvieaeis known as a Gram-positive, catalase-negative, and facultatively anaerobic fish pathogen. The association betweenLactococcusspp. and human infectious diseases is described as being mainly associated with lumbar osteomyelitis, hepatic abscess, and infective endocarditis. In the literature of orthopedic post-prosthetic infections,L. garvieaewas associated with a case of hip prosthetic infection in a fishmonger woman. We present the case of a 79-year-old male patient with multiple comorbidities, who is admitted to our center with a 5-day history of pain, swelling, and motility disorder of the right knee by the presence of a bicondylar knee replacement surgery, which was performed due to gonarthrosis 17 years ago. The radiographies of the right knee revealed no signs of displacement or loosening of the prothesis. After multiple radical debridements including VAC therapy and targeted antibiotic therapy we have managed to defeat the infection without exchange arthroplasty. Although we could not demonstrate the source of infection, we can only presume that in our case the source of infection was represented by the ingestion of possibly contaminated food. The patient had a habit of eating Nile perch fish (Lates niloticus) every 4 weeks. We illustrated once more the possibility of a late onsetL. garvieaerelated orthopedic periprosthetic joint infection by multiple comorbidities.

Psoriasis Vulgaris Caused by Ceramic Inserts Used in Total Hip Replacement

2012 ◽  
Vol 16 (6) ◽  
pp. 448-450 ◽  
Author(s):  
Fujio Higuchi ◽  
Daisuke Tsuruta ◽  
Yumiko Ishibashi ◽  
Kazuko Imamura ◽  
Tokiko Shimoyama ◽  
...  
Keyword(s):  
Nous Avons ◽  
Total Hip Replacement ◽  
Hip Joint ◽  
Hip Replacement ◽  
Nuclear Factor Κb ◽  
Total Hip ◽  
First Case ◽  
The Right ◽  
Ceramic Insert ◽  
Psoriatic Lesions

Background: Ceramics are inorganic nonmetallic materials and are used as bioinert components in joint replacement surgeries. Ceramics are known to be low allergenic. We experienced a ceramic-induced psoriasis. Objective: We report a first case of possible ceramic-induced psoriasis caused by a ceramic insert. Methods: A 55-year-old female received an implanted ceramic-on-ceramic total hip replacement for osteoarthritis of the right hip joint. Following surgery, she developed psoriatic lesions, which continued for 10 years. We suspected that psoriasis was caused by a ceramic insert and removed it surgically. Results: When the ceramic insert was replaced with a polyethylene-on-metal hip joint, the psoriatic lesions completely disappeared. Conclusion: The pathogenesis of psoriasis is still an enigma, although deregulation of nuclear factor κB signaling and resulting abnormal cytokine secretion are speculated to be involved. Ceramics may affect these signaling events and cause the onset of psoriasis. Renseignements de base: Les céramiques sont des matériaux non métalliques inorganiques et sont utilisées comme composants bio-inertes dans les arthroplasties. Les céramiques sont reconnues pour être peu allergisantes. Nous avons observé un psoriasis provoqué par la céramique. Objectif: Nous exposons un premier cas possible de psoriasis provoqué par la céramique causé par un implant en céramique. Méthodes: Une femme de 55 ans a reçu une prothèse céramique-sur-céramique implantée lors d'une arthroplastie totale de la hanche pour traiter l'arthrose de l'articulation de la hanche droite. Après la chirurgie, elle a développé des lésions psoriasiques dont la manifestation s'est poursuivie pendant 10 ans. Nous avons soupçonné que le psoriasis était causé par l'implant en céramique, et nous l'avons enlevé chirurgicalement. Résultats: Une fois l'implant en céramique remplacé par une prothèse articulaire en polyéthylène-sur-métal, les lésions psoriasiques ont disparu complètement. Conclusion: La pathogenèse du psoriasis demeure une énigme, bien qu'on suppose que la dérégulation de la voie de signalisation NF-κB et que la sécrétion anormale de cytokines résultante soient impliquées. Les céramiques peuvent affecter ces événements de signalisation et provoquer l'apparition du psoriasis.

A Case of Periprosthetic Joint Infection Because of Rothia Mucilaginosa

2021 ◽  
Author(s):  
Janse T Schermerhorn ◽  
Donald F Colantonio ◽  
Derek T Larson ◽  
Robert J McGill
Keyword(s):  
Knee Arthroplasty ◽  
Periprosthetic Joint Infection ◽  
Joint Infection ◽  
Diagnostic Delay ◽  
Infectious Agent ◽  
Two Stage ◽  
Treatment Regimens ◽  
History Of ◽  
Rothia Mucilaginosa ◽  
One Year

ABSTRACT Periprosthetic joint infection (PJI) is a rare but devastating complication of total joint arthroplasty. Identifying the offending infectious agent is essential to appropriate treatment, and uncommon pathogens often lead to a diagnostic delay. This case describes the first known instance of a total knee arthroplasty (TKA) with Rothia mucilaginosa, a typical respiratory tract organism. This report aims to provide insight into the treatment of this atypical PJI, as there are only six previously published cases of Rothia species PJI septic arthritis. The patient is a 64-year-old diabetic male who underwent a right TKA and left TKA ∼6 months later. Approximately 3 weeks status post-left TKA, he showed evidence of left PJI. One year after treatment and recovery from his left PJI, he presented with several months of right knee pain and fatigue. Subsequent labs and imaging revealed right PJI. No recent history of dental disease or work was observed. He then underwent two-stage revision right knee arthroplasty and microbial cultures yielded Rothia mucilaginosa. After initial empiric treatment, antibiotic therapy was narrowed to 6 weeks of vancomycin. Following negative aspiration cultures the patient underwent reimplantation of right TKA components. One year following treatment, the patient was fully recovered with no evidence of infection. This case emphasizes the possibility of microbial persistence despite various antibiotic treatment regimens for the patient’s contralateral knee arthroplasty and PJI. Additionally, this case demonstrates the importance of two-stage revision in patients with PJI, and the viability of treating Rothia species PJIs with vancomycin.

scholarly journals Periprosthetic Joint Infection Increases the Risk of One-Year Mortality

2013 ◽  
Vol 95 (24) ◽  
pp. 2177-2184 ◽  
Author(s):  
Benjamin Zmistowski ◽  
Joseph A Karam ◽  
Joel B Durinka ◽  
David S Casper ◽  
Javad Parvizi
Keyword(s):  
Periprosthetic Joint Infection ◽  
Joint Infection ◽  
One Year

scholarly journals Copper-Coated Spacer for Total Femoral Replacement in Recurrent Periprosthetic Joint Infection: A Case Report

2021 ◽  
Vol 27 (1) ◽  
pp. 175-182
Author(s):  
A. Belokobylov ◽  
N. D. Batpenov ◽  
S. S. Balgazarov ◽  
V. D. Serikbayev ◽  
A. A. Krikliviy ◽  
...  
Keyword(s):  
Total Hip Arthroplasty ◽  
Hip Arthroplasty ◽  
Periprosthetic Joint Infection ◽  
Joint Infection ◽  
Sinus Tract ◽  
Knee Joints ◽  
Cement Spacer ◽  
Total Hip ◽  
The Right ◽  
Postoperative Scar

Background. There are few cases of entire femur modular replacement with hip and knee joints in patients with periprosthetic joint infection (PJI) in literature. They report encouraging results in patients of elderly and senile age. We present case of a copper-coated femoral spacer implantation to 50-year-old patient with multiple PJI episodes and osteomyelitis of the entire femur.Clinical presentation. A 40-year-old male patient after resection of the proximal part of the right femur for fibrotic osteodysplasia underwent total hip arthroplasty with replacement of 15 cm of the femur. In December 2010 (20 months after implantation), instability of the femoral component developed, revision arthroplasty was performed with stem recementation. After 4 months, sinus tract formed in the area of the postoperative scar. After another 4 months, the head of the prosthesis was dislocated. In September 2011, the endoprosthesis components were removed and a unipolar cement spacer was implanted. The limb immobilized in a hip spica cast. Methicillin-sensitive S. epidermidis (MSSE) was detected in the preoperative joint aspiration puncture and periprosthetic tissues. After 3 months (December 2011), patient underwent revision total hip arthroplasty (25 cm defect was replaced). 5 years of PJI remission followed. In November 2016 after PJI recurrence the endoprosthesis was removed, and an articulating spacer was implanted. P. aeruginosa was detected in periprosthetic tissues. For the past 2.5 years there were periodically sinus tracts formations. In August of 2019 spacer’s migration resulted in an intercondylar fracture of the right femur. In September 2019, spacer was removed, and MSSE was detected in the surrounding tissues. An articulating cement spacer based on an oncological modular total femur coppercoated endoprosthesis was implanted. At each control examination during the year copper concentration in blood serum was determined, it did not exceed 900–1200 mcg/l. No local or systemic side effects were detected. The patient started working 3 months after surgery. After 6 months poor functioning sinus tract formed in the postoperative scar area in the lower third of the thigh. 1.5 years after the operation, the functional condition is satisfactory.Conclusion. The use of the copper-coated spacer based on modular total femur endoprosthesis with hip and knee joints in a patient with multiple PJI allowed to improve the function of the limb and reduce the severity of the infectious process. No local or systemic toxic effects of copper were detected.

Next-generation sequencing not superior to culture in periprosthetic joint infection diagnosis

2021 ◽  
Vol 103-B (1) ◽  
pp. 26-31
Author(s):  
Beau J. Kildow ◽  
Sean P. Ryan ◽  
Richard Danilkowicz ◽  
Alexander L. Lazarides ◽  
Colin Penrose ◽  
...  
Keyword(s):  
Next Generation Sequencing ◽  
Periprosthetic Joint Infection ◽  
Joint Infection ◽  
Next Generation ◽  
Sample Collection ◽  
Tissue Samples ◽  
Musculoskeletal Infection ◽  
Conventional Culture ◽  
Significant Difference ◽  
Generation Sequencing

Aims Use of molecular sequencing methods in periprosthetic joint infection (PJI) diagnosis and organism identification have gained popularity. Next-generation sequencing (NGS) is a potentially powerful tool that is now commercially available. The purpose of this study was to compare the diagnostic accuracy of NGS, polymerase chain reaction (PCR), conventional culture, the Musculoskeletal Infection Society (MSIS) criteria, and the recently proposed criteria by Parvizi et al in the diagnosis of PJI. Methods In this retrospective study, aspirates or tissue samples were collected in 30 revision and 86 primary arthroplasties for routine diagnostic investigation for PJI and sent to the laboratory for NGS and PCR. Concordance along with statistical differences between diagnostic studies were calculated. Results Using the MSIS criteria to diagnose PJI as the reference standard, the sensitivity and specificity of NGS were 60.9% and 89.9%, respectively, while culture resulted in sensitivity of 76.9% and specificity of 95.3%. PCR had a low sensitivity of 18.4%. There was no significant difference based on sample collection method (tissue swab or synovial fluid) (p = 0.760). There were 11 samples that were culture-positive and NGS-negative, of which eight met MSIS criteria for diagnosing infection. Conclusion In our series, NGS did not provide superior sensitivity or specificity results compared to culture. PCR has little utility as a standalone test for PJI diagnosis with a sensitivity of only 18.4%. Currently, several laboratory tests for PJI diagnosis should be obtained along with the overall clinical picture to help guide decision-making for PJI treatment. Cite this article: Bone Joint J 2021;103-B(1):26–31.

HIP JOINT INFECTION CAUSED BY SHIGELLA SONNEI IN A ONE-YEAR-OLD BOY

1994 ◽  
Vol 13 (12) ◽  
pp. 1156-1157 ◽  
Author(s):  
Robin L. Altman ◽  
Karl I. Li ◽  
Fern Juster ◽  
Kenneth G. Van Horn ◽  
Iris Schlesinger ◽  
...  
Keyword(s):  
Hip Joint ◽  
Joint Infection ◽  
Shigella Sonnei ◽  
One Year

scholarly journals Primary adrenocortical sarcomatoid carcinoma: Report of a case

2012 ◽  
Vol 6 (5) ◽  
Author(s):  
Jia-jun Yan ◽  
Ai-jing Sun ◽  
Yu Ren ◽  
Chuanlin Hou
Keyword(s):  
Adrenal Gland ◽  
Sarcomatoid Carcinoma ◽  
Final Diagnosis ◽  
Pathologic Examination ◽  
First Case ◽  
Complete Tumour ◽  
One Year ◽  
The One ◽  
The Right

We report the case of a 72-year-old man with a right adrenocortical mass who had undergone complete tumour excision with the adrenal gland and around adipose tissue. Pathologic examination led to a final diagnosis of primary sarcomatoid carcinoma of the right adrenal gland. The patient was without recurrence at the one year follow-up. To our knowledge, this is the first case in China and the second reported case in English published studies.

Sign in / Sign up

Export Citation Format

Share Document