Physical health-related quality of life at higher achieved hemoglobin levels among chronic kidney disease patients: a systematic review and meta-analysis

Introduction: During the past few decades, health related quality of life has been considered as an important predictor for positive health outcomes. Health-related quality of life assessment helps in determining the impact of disease on the everyday life of patients. Chronic kidney disease severely affects health related quality of life of patient. Objective: The objective of this study was to assess health related quality of life among patients with chronic kidney diseases in Pakistan. Methodology: A descriptive cross-sectional study design was used. Study respondents included CKD pre-dialysis and dialysis patients with or without comorbidities visiting tertiary care facilities located in twin cities of Pakistan. Sample size was calculated to be 386 pharmacists to achieve 95% confidence level with 5% margin of error. Convenient sampling technique was used to select respondents. A pre- validated questionnaire Kidney Disease Quality of Life questionnaire (KDQoL-36) was used. Data was coded and analyzed using SPSS 21 after collection. Mann-Whitney and Kruskal-Wallis (p ≥ 0.05) tests were according to different demographic variables. Results: The results of the current study showed lowest scores for HRQoL in domain of physical health composite (30.77±11.16) followed by domain of symptoms and problems associated with CKD whereas daily life had the highest scores. The results highlighted that females had better HRQoL in all domains mental health (46.30, ± 8.73), burden of kidney disease (69.47, ± 32.35), symptoms (29.79, ± 31.22) and effect of disease on daily activities (40.96, ± 32.11) while lowest score for physical health (30.90, ± 10.34). Married respondents had better HRQoL among all domains than unmarried patients except for physical health (32.26, ± 10.7). A significant difference (p ≥ 0.05) was observed among different domains of HRQoL of CKD patients with respect to different genders, marital status, age groups and qualification levels. Males had relatively better physical health scores but their daily activities were also affected more by their disease. Married respondents had relatively better HRQoL among all domains than unmarried patients except for physical health. No significant difference (p ≥ 0.05) was observed for different stages of disease. Conclusion: The present study concluded that patients with CKD had poor HRQoL regardless of novel treatments availability. A negative impact was observed across all domains of health related quality of life among chronic kidney disease patients. Necessary programs focusing on health education for patients with low literacy levels should be initiated to increase health awareness and improve mental health among CKD patients.

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A Systematic Review Of Health-Related Quality Of Life Assessment For Children And Adolescents With Chronic Kidney Disease

Value in Health ◽

10.1016/j.jval.2014.03.1714 ◽

2014 ◽

Vol 17 (3) ◽

pp. A294-A295

Author(s):

A.V. Thach ◽

S. Jiang ◽

K.L. Rascati

Keyword(s):

Quality Of Life ◽

Systematic Review ◽

Chronic Kidney Disease ◽

Kidney Disease ◽

Life Assessment ◽

Health Related Quality ◽

Quality Of Life Assessment ◽

Related Quality ◽

Health Related

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Impact of chronic kidney disease on health-related quality of life in the pediatric population: meta-analysis

Jornal de Pediatria ◽

10.1016/j.jped.2020.10.013 ◽

2020 ◽

Author(s):

Keydis Sulay Ruidiaz-Gómez ◽

Luis Felipe Higuita-Gutiérrez

Keyword(s):

Quality Of Life ◽

Chronic Kidney Disease ◽

Kidney Disease ◽

Pediatric Population ◽

Meta Analysis ◽

Health Related Quality ◽

Related Quality ◽

Health Related

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Health Related-Quality of Life in CKD and Dialysis Patients in Asian Countries : A Systematic Review

ARKESMAS (Arsip Kesehatan Masyarakat) ◽

10.22236/arkesmas.v3i2.3007 ◽

2018 ◽

Vol 3 (2) ◽

pp. 50-55

Author(s):

Aan Anjarwati

Keyword(s):

Quality Of Life ◽

Systematic Review ◽

Chronic Kidney Disease ◽

Kidney Disease ◽

Health Related Quality ◽

Asian Countries ◽

Quality Life ◽

Related Quality ◽

Health Related

ABSTRACT Introduction: Chronic Kidney Disease (CKD) and Chronic dialysis has a great impact on patients health-related quality of life (HRQOL). The impacts are about the morbidity, mortality, and the survival rate of the dialysis therapy. We focused this systematic review in Asian countries. Methods: Systematic Review with PRISMA method retrieved from online database such as PubMed, Wiley and ProQuest using a keyword “Health Related-Quality Life (HRQOL)”, “Chronic Kidney Disease (CKD) patient OR ESRD (End Stage Renal Disease), CKD with Hemodialysis OR CKD dialysis at Asian Country”. The end of this search we got 10 journals. Results: The measurement HRQOL in CKD or dyalisis patients such EQ-5D and Kidney Disease Quality of Life (KDQOL). There are 4 country used KDQL (Korea, China, India, Singapore and Indonesia). The result show HRQOL in CKD patients has declined when the level of CKD increased especially when the amount of albumin high and the level of hemoglobin decline. HRQOL in dialysis patient has lower depressive mood in planned dialysis group than unplanned dialysis. There are no difference in KDCS, PCS, or MCS scores between patients treated by hemodialysis and CAPD. They also got 5 more years when choose dialysis (Hemodialysis). Conclusion: Health related quality of life (HRQOL) related with progressive of CKD level. The level that should pay attention is CKD level 3 where HRQOL can decreased. When the patients routine dialysis (CAPD or hemodialysis) used concern about the medicine (such erythropoietin, routine medicine) and the laboratory (albumin and hemoglobin). The more progressive level of CKD the lower of HRQOL. Keywords: Health Related Quality of Life (HQOL), CKD (Chronic Kidney Disease), Dialysis, Hemodialysis, Continuous Ambulatory Peritoneal Dialysis (CAPD).

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