scholarly journals Plasma concentrations of leptin at mid-pregnancy are associated with gestational weight gain among pregnant women in Tanzania: a prospective cohort study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Dongqing Wang ◽  
Anne Marie Darling ◽  
Chloe R. McDonald ◽  
Nandita Perumal ◽  
Enju Liu ◽  
...  
Keyword(s):  
Weight Gain ◽  
Pregnant Women ◽  
Gestational Weight Gain ◽  
Risk Ratio ◽  
Plasma Concentrations ◽  
Mean Difference ◽  
Gestational Weight ◽  
Excessive Gestational Weight Gain ◽  
Maternal Metabolism ◽  
Plasma Leptin

Abstract Background Gestational weight gain (GWG) has critical implications for maternal and child health. Inflammation and angiogenesis are implicated in various aspects of maternal metabolism that may play a role in gestational weight gain. The associations of inflammatory, angiogenic, and metabolic pathways with GWG are yet to be elucidated. This study evaluated associations between a panel of inflammatory, angiogenic, and metabolic proteins measured in mid-pregnancy and gestational weight gain. Methods Pregnant women were enrolled from Dar es Salaam, Tanzania, between 2001 and 2004. The participants were enrolled at mid-pregnancy (12 to 27 weeks of gestation) and followed up until delivery. This analysis focused on a cohort of 1002 women who were primigravid, had singleton live births, had longitudinal measures of gestational weight, and whose mid-pregnancy plasma samples underwent analysis for 18 proteins. Results Higher plasma concentrations of leptin (mean difference in GWG percent adequacy comparing highest with lowest quartiles: 10.24; 95% CI 3.31, 17.16; p-trend = 0.003) and chitinase-3-like protein-1 (CH3L1) (mean difference in GWG percent adequacy comparing highest with lowest quartiles: 7.02; 95% CI 0.31, 13.72; p-trend = 0.007) were associated with greater GWG in a dose-response pattern. Higher leptin concentrations were associated with a lower risk of inadequate GWG (risk ratio comparing highest with lowest quartiles: 0.77; 95% CI 0.65, 0.91; p-trend = 0.001) and a higher risk of excessive GWG (risk ratio comparing highest with lowest quartiles: 1.57; 95% CI 1.03, 2.39; p-trend = 0.03). Higher CH3L1 concentrations were associated with a higher risk of excessive GWG (p-trend = 0.007). The associations of leptin and CH3L1 with inadequate GWG were stronger during the second than the third trimester. The other 16 proteins examined were not significantly associated with GWG. Conclusions Mid-pregnancy plasma leptin concentrations may be associated with GWG and have clinical predictive utility in identifying women at a higher risk of inadequate or excessive gestational weight gain.

scholarly journals Determining Acceptability of a Text-message Based Intervention to Prevent Excessive Gestational Weight Gain in Low-income Women in Hawai'i WIC (P04-029-19)

2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Dustin Valdez ◽  
Cristina Palacios ◽  
Jinan Banna
Keyword(s):  
Weight Gain ◽  
Pregnant Women ◽  
Gestational Weight Gain ◽  
Low Income ◽  
Text Message ◽  
Healthy Food ◽  
Nutrition Intervention ◽  
Gestational Weight ◽  
Excessive Gestational Weight Gain ◽  
Low Income Women

Abstract Objectives The purpose of this study was to determine the acceptability of messages in a text message-based nutrition intervention for the prevention of excessive gestational weight gain in low-income women in the Women, Infants, and Children (WIC) program in Hawai‘i. Methods Low-income pregnant women (n = 100) in Hawaii participated in a four-month text message-based nutrition intervention program. Participants in the intervention arm received 18 text messages (1/week) that focused on reinforcing WIC's nutritional recommendations for pregnant women. Participants who completed the intervention were interviewed at their respective WIC clinic about their experiences with the messages. The interviews were transcribed and content analysis to identify the prevailing themes and concepts was performed with NVivo (version 12, GSR International, Inc, Burlington, MA). Results Participants responded to questions in four content areas: most useful messages for staying healthy, least useful messages for staying healthy, messages that affected eating and exercise habits, and the experience of receiving messages. The most useful messages related to healthy food substitutions. The least helpful messages were those participants felt they were unable to perform, such as eating sardines for omega-3 fatty acids. Participants cited that messages relating to healthy food substitutions as having the most impact on eating behavior. Most participants also felt that increasing the number of messages would have been helpful. Conclusions Results suggest that providing information relating to healthy food substitutions as well as providing a high frequency of messages could be beneficial in the development of mobile health programs for low-income pregnant women in controlling gestational weight gain. Funding Sources Mountain West Clinical Translational Research Infrastructure Network under a grant from National Institute of General Medicine Sciences of the National Institute of Health.

scholarly journals Association Between Maternal Body Mass and Physical Activity Counseling During Pregnancy

2021 ◽  
Vol 12 ◽  
Author(s):  
Shelly Ruart ◽  
Stéphane Sinnapah ◽  
Olivier Hue ◽  
Eustase Janky ◽  
Sophie Antoine-Jonville
Keyword(s):  
Physical Activity ◽  
Weight Gain ◽  
Pregnant Women ◽  
Gestational Weight Gain ◽  
Weight Status ◽  
Maternal Obesity ◽  
Gestational Weight ◽  
Excessive Gestational Weight Gain ◽  
Weight Problem ◽  
Weight Problems

Aims: The antenatal period provides an important opportunity for giving advice on healthy lifestyle choices. However, the prevalence of maternal obesity is increasing, and women report that they do not receive counseling. We investigated the information given to pregnant women on gestational weight gain, physical activity, and nutrition during pregnancy in relation with their initial weight status, current gestational weight gain and diagnoses of either pre-pregnancy overweight/obesity or excessive gestational weight gain.Methods: Cross-sectional survey using a questionnaire. Pregnant participants (n = 141) were recruited from a midwife center. They completed a structured questionnaire on the information they received during their pregnancy and we assessed its relationship with their weight.Results: We found that many pregnant women did not receive advice about physical activity, gestational weight gain and nutrition (37.5, 53.2, and 66.2%, respectively). Women with weight problems (pre-pregnancy overweight/obesity and excessive gestational weight gain) were less targeted for counseling, although more than 80% of the women viewed receiving information on these topics as positive. Also, being informed of a weight problem was associated with a greater chance of receiving information about physical activity, gestational weight gain and nutrition (all p < 0.05). However, verbalization of the weight problems was low (14.0% of women with pre-pregnancy overweight were informed of their status).Conclusion: Health professionals should dispense more information, especially on PA and particularly for women with weight problems. Verbalization of the weight problem seems associated with more frequent transmission of information.

scholarly journals Pregnancy outcomes in women with excessive gestational weight gain in Dschang health district of Cameroon

2021 ◽  
Vol 7 (4) ◽  
pp. 239
Author(s):  
Skinner Lekelem Nguefack ◽  
Jackson Jr Ndenkeh ◽  
Cavin Bekolo ◽  
Bruno Kenfack
Keyword(s):  
Weight Gain ◽  
Pregnant Women ◽  
Gestational Weight Gain ◽  
Pregnancy Outcomes ◽  
Genital Tract ◽  
Health District ◽  
P Value ◽  
Prolonged Labour ◽  
Gestational Weight ◽  
Excessive Gestational Weight Gain

<p class="abstract"><strong>Background:</strong> Excessive gestational weight gain (EGWG) during pregnancy can lead to adverse outcomes for the mother and/or the new-born. The aim of the study was to determine the prevalence of EGWG as well as its effect on pregnancy outcomes amongst pregnant women at the health district of Dschang in Cameroon.  </p><p class="abstract"><strong>Methods:</strong> This was a cross sectional study conducted from January to June 2019 and targeting all consenting pregnant women in Dschang District Hospital. They were administered a prepared questionnaire followed by their body mass index measurements for times at the beginning and the end of gestation to measure GWG. Logistic regression was used to determine the association of the EGWG to some particular pregnancy outcomes, adjusting for other factors with significance set at 5%.   </p><p class="abstract"><strong>Results:</strong> A total of 400 women were included in this study with a mean age of 27±5years, 59.2% being married and 34.8% still being students. Also it was noted that 24.8% of these women were obese while 25.3% had EGWG. Furthermore, EGWG was independently associated to prolonged labour (aOR=2.4; CI: 1.3-4.6; p value=0.007), genital tract laceration (aOR=2.0; CI: 1.0-3.8; p value=0.036) and foetal macrosomia (aOR=7.3; CI: 3.5-15.2; p value&lt;0.001).</p><p class="abstract"><strong>Conclusions:</strong> The prevalence of EGWG was high and it was associated with prolonged labour, genital tract laceration and foetal macrosomia. There is thus the need to improve the awareness of these women on EGWG as well as a constant follow up all through gestational period so as to regulate their GWG. The above measures will help to reduce occurrence of these complications, and consequently reduce maternal and neonatal mortality.</p><p class="abstract"> </p>

scholarly journals Morphological features of the placenta in pregnant women with excessive gestational weight gain

2020 ◽  
Vol 20 (1-2) ◽  
pp. 6-12
Author(s):  
Anna S. Vachrushina ◽  
Anna S. Krivenko ◽  
Svetlana D. Moiseenkova ◽  
Anastasiya S. Ogareva ◽  
Vita N. Pokusaeva
Keyword(s):  
Weight Gain ◽  
Pregnant Women ◽  
Gestational Weight Gain ◽  
Fatty Degeneration ◽  
Study Objective ◽  
Gestational Weight ◽  
Excessive Gestational Weight Gain ◽  
Study Results ◽  
Microscopic Evaluation ◽  
Microscopic Morphology

Study objective. To evaluate the association between the placenta and excessive gestational weight gain (GWG). Materials and methods. A prospective cohort study included the standard ultrasonography with subsequent microscopic morphology of the placenta in term pregnancy. Of 83 examined pregnant women, 46 had excessive GWG and 37 had recommended one. In addition, intensity of lipid infiltration was investigated in 24 placentas (12 in each group). Study results. Excessive GWG resulted in significant enlargement of placenta which resulted in greater neonatal weight. Ultrasonography and subsequent microscopic evaluation revealed placentas to be less efficient in case of excessive GWG. Conclusions. These findings indicated that excessive GWG influenced placental morphology. Future studies are necessary to determine accumulation of fat in placentas and membranes in case of excessive GWG, which can be defined as fatty degeneration.

Identification of Problems and Needs When Designing an mHealth App for Overweight and Obese Pregnant Women to Prevent Excessive Gestational Weight Gain: A Focus Group Study (Preprint)

2020 ◽  
Author(s):  
Ching-Fang Lee ◽  
Li-Kang Chi ◽  
Jian-Pei Huang ◽  
Chen-Ju Lin
Keyword(s):  
Weight Gain ◽  
Focus Group ◽  
Pregnant Women ◽  
Gestational Weight Gain ◽  
Healthcare Providers ◽  
Adverse Outcomes ◽  
Obese Women ◽  
Focus Group Study ◽  
Gestational Weight ◽  
Excessive Gestational Weight Gain

BACKGROUND Overweight and obese women tend to gain excessive weight and have adverse outcomes during pregnancy. Despite the increasing number of health-related apps, there is still a lack of a user-based app to help prevent excessive gestational weight gain (GWG) and extend the longevity of the changes in behavior needed to maintain a woman’s optimal weight during pregnancy. OBJECTIVE The aim of this study was to identify the problems and needs for designing an mHealth app for obese and overweight pregnant women that they can continue to use to control their GWG. METHODS We used a qualitative interpretive approach and analytical induction to present the findings of three focus group sessions involving 13 overweight and obese pregnant women in Taipei, Taiwan. This study was conducted from July to October 2019. RESULTS Five problems and 10 needs were identified related to the use of an app to control overweight and obese women’s GWG. These problems were 1) an information gap, 2) a lack of support, 3) perceived complications of using the app(s), 4) easily forgetting the app(s), and 5) low motivation. The 10 main needs were 1) prenatal examination, 2) credible information, 3) short and easily understandable information, 4) a network community of peer support, 5) feedback from and interaction with healthcare providers, 6) a convenient and user-friendly interface, 7) goal-setting, 8) evaluation and tracking, 9) reminders, and 10) incentives for systematic celebrations and rewarding success. CONCLUSIONS The results of this study will help in the development of a user-based app that serves as a guide based on evidenced and informative practices. CLINICALTRIAL No

Sign in / Sign up

Export Citation Format

Share Document