Insluin and epithelial growth factor (EGF) promote programmed death ligand 1(PD-L1) production and transport in colon cancer stem cells

Mo1923 Inhibition of Insulin-Like Growth Factor Receptor Activity Attenuates Colon Cancer Stem Cells Growth and Self-Renewal by Targeting Mevlonate-Isoprenoid Metabolism

Gastroenterology ◽

10.1016/s0016-5085(14)62513-0 ◽

2014 ◽

Vol 146 (5) ◽

pp. S-692

Author(s):

Chetna Sharon ◽

Jagrut Patel ◽

Nirmita J. Patel ◽

Somesh Baranwal ◽

Bhaumik B. Patel

Keyword(s):

Stem Cells ◽

Colon Cancer ◽

Growth Factor ◽

Cancer Stem Cells ◽

Growth Factor Receptor ◽

Receptor Activity ◽

Self Renewal ◽

Colon Cancer Stem Cells ◽

Isoprenoid Metabolism

Study of the interaction among Notch pathway receptors, correlation with stemness, as well as their interaction with CD44, dipeptidyl peptidase-IV, hepatocyte growth factor receptor and the SETMAR transferase, in colon cancer stem cells

Journal of Receptors and Signal Transduction ◽

10.3109/10799893.2013.828072 ◽

2013 ◽

Vol 33 (6) ◽

pp. 353-358 ◽

Cited By ~ 11

Author(s):

Panagiotis Apostolou ◽

Maria Toloudi ◽

Eleni Ioannou ◽

Eleni Kourtidou ◽

Marina Chatziioannou ◽

...

Keyword(s):

Stem Cells ◽

Colon Cancer ◽

Growth Factor ◽

Cancer Stem Cells ◽

Hepatocyte Growth Factor ◽

Notch Pathway ◽

Growth Factor Receptor ◽

Colon Cancer Stem Cells ◽

Hepatocyte Growth Factor Receptor ◽

Hepatocyte Growth

Abstract 4667: A synergistic combination strategy for optimal inhibition of colon cancer stem cells: Simultaneous inhibition of Insulin-like growth factor-1 receptor-AKT-mammalian target of rapamycin axis and the mevalonate-isoprenoid biosynthetic pathway

10.1158/1538-7445.sabcs18-4667 ◽

2019 ◽

Author(s):

Chetna Sharon ◽

Rio Boothello ◽

Alberto Vera ◽

Bhaumik B. Patel

Keyword(s):

Stem Cells ◽

Colon Cancer ◽

Growth Factor ◽

Cancer Stem Cells ◽

Biosynthetic Pathway ◽

Mammalian Target Of Rapamycin ◽

Combination Strategy ◽

Colon Cancer Stem Cells ◽

Simultaneous Inhibition

The clinical and biological roles of transforming growth factor beta in colon cancer stem cells: A systematic review

European Journal of Cell Biology ◽

10.1016/j.ejcb.2017.11.001 ◽

2018 ◽

Vol 97 (1) ◽

pp. 15-22 ◽

Cited By ~ 13

Author(s):

Anna Chruścik ◽

Vinod Gopalan ◽

Alfred King-yin Lam

Keyword(s):

Systematic Review ◽

Stem Cells ◽

Colon Cancer ◽

Growth Factor ◽

Cancer Stem Cells ◽

Transforming Growth Factor Beta ◽

Transforming Growth Factor ◽

Colon Cancer Stem Cells ◽

Growth Factor Beta

Abstract 4667: A synergistic combination strategy for optimal inhibition of colon cancer stem cells: Simultaneous inhibition of Insulin-like growth factor-1 receptor-AKT-mammalian target of rapamycin axis and the mevalonate-isoprenoid biosynthetic pathway

10.1158/1538-7445.am2019-4667 ◽

2019 ◽

Author(s):

Chetna Sharon ◽

Rio Boothello ◽

Alberto Vera ◽

Bhaumik B. Patel

Keyword(s):

Stem Cells ◽

Colon Cancer ◽

Growth Factor ◽

Cancer Stem Cells ◽

Biosynthetic Pathway ◽

Mammalian Target Of Rapamycin ◽

Combination Strategy ◽

Colon Cancer Stem Cells ◽

Simultaneous Inhibition

Human colon cancer stem cells are enriched by insulin-like growth factor-1 and are sensitive to figitumumab

Cell Cycle ◽

10.4161/cc.10.14.16418 ◽

2011 ◽

Vol 10 (14) ◽

pp. 2331-2338 ◽

Cited By ~ 37

Author(s):

Lori S. Hart ◽

Nathan G. Dolloff ◽

David T. Dicker ◽

Constantinos Koumenis ◽

James G. Christensen ◽

...

Keyword(s):

Stem Cells ◽

Colon Cancer ◽

Growth Factor ◽

Cancer Stem Cells ◽

Human Colon ◽

Human Colon Cancer ◽

Betulinic Acid Kills Colon Cancer Stem Cells

Current Stem Cell Research & Therapy ◽

10.2174/1574888x11666151203223512 ◽

2016 ◽

Vol 11 (5) ◽

pp. 427-433 ◽

Cited By ~ 20

Author(s):

Lisette Potze ◽

Simone di Franco ◽

Jan H. Kessler ◽

Giorgio Stassi ◽

Jan Paul Medema

Keyword(s):

Stem Cells ◽

Colon Cancer ◽

Cancer Stem Cells ◽

Betulinic Acid ◽

Aberrant expression of redox protein Ape1 in colon cancer stem cells

Oncology Letters ◽

10.3892/ol.2014.1864 ◽

2014 ◽

Vol 7 (4) ◽

pp. 1078-1082 ◽

Cited By ~ 17

Author(s):

DEBAO LOU ◽

LINA ZHU ◽

HUAWEI DING ◽

HAI-YAN DAI ◽

GANG-MING ZOU

Keyword(s):

Stem Cells ◽

Colon Cancer ◽

Cancer Stem Cells ◽

Aberrant Expression ◽

Redox Protein ◽

Non-Canonical Hedgehog Signaling Is a Positive Regulator of the WNT Pathway and Is Required for the Survival of Colon Cancer Stem Cells

Cell Reports ◽

10.1016/j.celrep.2017.11.025 ◽

2017 ◽

Vol 21 (10) ◽

pp. 2813-2828 ◽

Cited By ~ 40

Author(s):

Joseph L. Regan ◽

Dirk Schumacher ◽

Stephanie Staudte ◽

Andreas Steffen ◽

Johannes Haybaeck ◽

...

Keyword(s):

Stem Cells ◽

Colon Cancer ◽

Cancer Stem Cells ◽

Hedgehog Signaling ◽

Wnt Pathway ◽

Positive Regulator ◽

435: Identification of hypoxia-induced miRNAs in colon cancer stem cells

European Journal of Cancer ◽

10.1016/s0959-8049(14)50389-9 ◽

2014 ◽

Vol 50 ◽

pp. S104-S105

Author(s):

P. Ullmann ◽

K. Baig ◽

W. Ammerlaan ◽

S. Haan ◽

E. Lettelier

Keyword(s):

Stem Cells ◽

Colon Cancer ◽

Cancer Stem Cells ◽