scholarly journals A case of anterior persistent hyperplastic primary vitreous associated with morning glory disc anomaly and retinopathy of prematurity like retinopathy in a term-born child

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Hao Zhang ◽  
Kaiqin She ◽  
Fang Lu
Keyword(s):  
Birth Weight ◽  
Optic Disc ◽  
Retinopathy Of Prematurity ◽  
High Sensitivity ◽  
Normal Weight ◽  
Term Infant ◽  
Morning Glory ◽  
Normal Birth ◽  
Persistent Hyperplastic Primary Vitreous ◽  
Morning Glory Disc Anomaly

Abstract Background Association of morning glory disc anomaly (MGDA) with persistent hyperplastic primary vitreous (PHPV) has been reported earlier. Retinopathy of prematurity (ROP) like retinopathy in preterm babies with optic disc anomalies has also been published. Our case is unique in terms of presence MGDA, PHPV, unilateral ROP like retinopathy in a term infant with normal birth weight. Case presentation A 5-month-old girl, born at term with a birth weight of 3750 g, presented with anterior PHPV, MGDA and ROP like retinopathy. In order to prevent retinal detachment, she received 360 degree barrage laser photocoagulation at the edge of the optic disc excavation of the left eye. In the follow-up a month later, laser scars were found in her left fundus without other complications. Conclusion PHPV and MGDA with ROP like retinopathy in term and normal weight baby is rare. The peripheral avascular retinal area, caused by the dragging of the defected optic disc, might have been more vulnerable to the oxygen change after birth which resulted in ROP like retinopathy. High sensitivity to oxygen results in a series of changes such as upregulation of VEGF and IGF-1 may cause ROP-like retinopathy.

Optic Disc Pulsation in a Morning Glory Disc Anomaly

2019 ◽  
Vol 3 (6) ◽  
pp. 534
Author(s):  
Avner Hostovsky ◽  
Leslie D. Mackeen ◽  
Elise Heon
Keyword(s):  
Optic Disc ◽  
Morning Glory ◽  
Morning Glory Disc Anomaly

scholarly journals Differential Diagnosis of Retinopathy of Prematurity

2018 ◽  
pp. 73-77
Keyword(s):  
Differential Diagnosis ◽  
Birth Weight ◽  
Retinopathy Of Prematurity ◽  
Incontinentia Pigmenti ◽  
Normal Birth Weight ◽  
Childhood Blindness ◽  
Norrie Disease ◽  
Normal Birth ◽  
Preterm Babies ◽  
Retinal Pathologies

Retinopathy of prematurity (ROP) which is a proliferative vitreoretinopathy is seen in preterm babies has become one of the main causes of preventable childhood blindness in the developing countries. Nowadays, the survival rate of preterm babies who have low birth weight has been increasing thanks to neonatal advances. For this reason, the incidence of ROP has increased in recent times. Similar retinal pathologies to ROP can be seen in the term babies with normal birth weight. In this review, it is aimed to be discussed in detail on the retinal vascular disorders that may be mistaken with ROP clinically such as familial exudative vitreoretinopathy, persistent fetal vasculopathy, Norrie disease, incontinentia pigmenti, and osteoporosis pseudoglioma.

scholarly journals Statistical Analysis of Birth Weight and Gender of Newborn Infants

2018 ◽  
pp. 1-7
Author(s):  
Jide Onyekwelu ◽  
Chike H. Nwankwo ◽  
I. C. A. Oyeka
Keyword(s):  
Birth Weight ◽  
Adult Life ◽  
Normal Weight ◽  
High Birth Weight ◽  
Normal Birth Weight ◽  
Weight Category ◽  
Normal Birth ◽  
Significant Difference ◽  
Males And Females ◽  
The Mean

Introduction: Birth weight is an important determinant of infant morbidity and mortality. Its effect extends upto adult life and may explain some non-communicable diseases that may occur in adult life. In general, males weigh more than females. Birth weight is categorised into three levels, viz., low, normal and high. This study analysed the relationship between gender and the categories of birth weights. Materials and Methods: Data on babies’ gender and birth weights from 961 term life deliveries in a private general practice hospital were analysed. Test on equality of the mean weight of males and females at the three categorical levels were done using z test and t-tests, as necessary. Results: Mean birth weight was found to be 3.30 ± 0.495 kg. Males weighed significantly heavier than females at mean weights of 3.343 ± 0.495 kg and 3.258 ± 0.490 kg, respectively. In the low birth weight category, males weighed 1.844 ± 0.297 kg and females weighed 1.992 ± 0.397 kg. There was no significant difference. Similarly, the mean weight of males and females in the high birth weight category were 4.462 ± 0.343 kg and 4.342 ± 0.219 kg, respectively with no significant difference. In the normal weight category, males weighed significantly more than the females with the mean weight of 3.30 ± 0.359 kg and 3.248 ± 0.392 kg, respectively. Conclusion: Male babies weighed more than female babies only in the normal birth weight category. The factor that selectively affected the birth weight of male babies must be acting under the category of normal birth weight only. More studies are necessary to identify the factors and the reasons, for which they act only at the level of the normal birth weight.  

scholarly journals Morbidity profile and immediate outcome of low birth weight neonates in a rural tertiary care hospital of Gujarat, India

2018 ◽  
Vol 5 (4) ◽  
pp. 1272
Author(s):  
Manish Rasania ◽  
Sunil Pathak ◽  
Prerna Dogra ◽  
Ayushi Jain ◽  
Neil Shah ◽  
...  
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Tertiary Care ◽  
Normal Weight ◽  
Health Improvement ◽  
Care Hospital ◽  
Normal Birth Weight ◽  
Mortality And Morbidity ◽  
Normal Birth ◽  
Partnership Model

Background: Low birth weight (LBW) has been defined as a birth weight of <2.5 kilogram regardless of gestational age. In India, every 3rd born child is of LBW. LBW is associated with increased neonatal mortality and morbidity, compromised growth and cognitive development.Methods: This is a retrospective cohort study using previously collected data from January 2015 to December 2015.Results: Out of 1238 live births, 485 (39.17%) were LBW. 456(94.01%) were LBW weighing >1500 grams (LBW), 22(4.53%) were VLBW, and 07(1.44%) were ELBW. 361(74.43%) were LBW2 (birth weight ≥2000 - <2500 grams), 95(19.58%) were LBW1 (birth weight ≥1500 - <2000 grams). 289(59.58%) of LBW neonates were full term. SNCU admission is significantly higher in LBW neonates (25.8% vs 9.61%). Morbidities were higher in LBW neonates compared to normal birth weight neonates. Difference was more significant in incidence of sepsis (3.72% vs 0.83%), RDS (2.19% vs 0%), TTN (5.48% vs 2.36%), hypoglycemia (1.31% vs 0%), feed intolerance (1.09% vs 0%) and risk of major congenital malformation (1.97% vs 0.27%). Need for respiratory support was 4.82% in LBW vs 2.36% in normal birth weight neonates. Morbidities were significantly higher in VLBW and ELBW neonates. Immediate poor outcome was in 3.92% in LBW neonates, while it was 0.56% in normal weight neonates. Poor immediate outcome was 1.11% in LBW2, 2.10% in LBW1, 10% in VLBW1, 41.66% IN VLBW2, and 100% in ELBW.Conclusions: LBW neonates are at higher risk of morbidities and mortalities. The major determinant for mortality in LBW babies is the birth weight. The best option to prevent LBW is by improving maternal health. Improvement of perinatal and neonatal services   in government sector and public private partnership model of free neonatal care can help to achieve the INAP goal of NMR <10 by 2030. 

scholarly journals Association between High-Sensitivity C-Reactive Protein and Blood Pressure among Children with History of Low Birth Weight Appropriate for Gestational Age, Low Birth Weight Small for Gestational Age, and Normal Birth Weight in Manado, North Sulawesi

2019 ◽  
Vol 2019 ◽  
pp. 1-10
Author(s):  
Adrian Umboh ◽  
Rocky Wilar ◽  
Valentine Umboh ◽  
Adi Suryadinata Krisetya
Keyword(s):  
Blood Pressure ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Gestational Age ◽  
High Sensitivity ◽  
Normal Birth ◽  
Reactive Protein ◽  
Appropriate For Gestational Age ◽  
History Of ◽  
Hs Crp

Over the past years, low birth weight (LBW) has been proven to be attributed to a wide variety of long-term morbidities, including hypertension. This study aimed to investigate the association between high-sensitivity C-reactive protein (hs-CRP) and blood pressure (BP) in children with a history of LBW appropriate for gestational age (LBW AGA), LBW small for gestational age (LBW SGA), and normal birth weight appropriate for gestational age (NBW AGA). The study cohort comprised children aged 9–12 years who were born in 2007–2010 at Prof. Dr. R. D. Kandou General Hospital Manado and resided in the city of Manado from March to August 2019. The children who met the inclusion criteria were evaluated for BP and hs-CRP level. A total of 120 children who met the inclusion criteria were enrolled in this study. Analysis for the association between LBW and NBW with systolic blood pressure (SBP) showed statistical significance (p=0.007). Linear regression analysis indicated a strongly significant influence of BW on serum hs-CRP level and SBP. Every 1 g increase in BW results in a decrease of serum hs-CRP level of 0.001 mg/L. Every 1 g increase in BW is attributed to 0.004 mmHg decrease in SBP. An increase in hs-CRP by 1 mg/L increases the SBP by 4.99 mmHg and DBP by 2.88 mmHg. LBW significantly correlates with hs-CRP level and higher SBP. A comprehensive education must be undertaken for the families who have children with LBW to reduce the risk of developing hypertension later in their life.

scholarly journals Effect of Artesunate on Peripheral Parasitaemia in Pregnant Women with Plasmodium Falciparum Infection

2017 ◽  
pp. 135
Author(s):  
Susi W Saragih ◽  
St. Maisuri T. Chalid ◽  
Umar Malinta ◽  
Isra Wahid
Keyword(s):  
Plasmodium Falciparum ◽  
Birth Weight ◽  
Pregnant Women ◽  
Obstet Gynecol ◽  
Normal Weight ◽  
Falciparum Infection ◽  
Smear Microscopy ◽  
Third Trimester ◽  
Normal Birth ◽  
Plasmodium Falciparum Infection

Objective: To determine the effect of artesunate on peripheral parasitaemia in pregnant women with Plasmodium falciparum infection. Methods: Pregnant women in second and third trimester with Plasmodium falciparum infection and their newborns were included in cohort prospective study in Sorong West Papua from September 2015 to February 2016. All pregnant women received 200 mg orally artesunate monotherapy for 7 days. Their newborns examined for weight at delivery and parasitaemia in placenta and cord blood. Parasitaemia diagnosis by Rapid Diagnostic Test and blood smear microscopy. Results: After artesunatemonotherapy, 82.5% (33/40) malariainfected pregnant women had negative parasitaemia (p=0.000) although 17.5% (7/40) of the pregnant women had positive parasitaemia. Parasitaemia also found in 10% (4/40) of placenta and 7.5% (3/40) of umbilical cord from newborns of malaria-infected pregnant women treated with artesunate. 70% (28/40) of the newborns in this study had normal weight. Conclusion: Artesunate reduces peripheral parasitaemia in the second and third trimester of pregnancy, and is associated with normal birth weight. [Indones J Obstet Gynecol 2017; 5-3: 135-138] Keywords: artesunate, low birth weight, peripheral parasitaemia

Retinal Detachment associated with Optic Nerve Anomalies: Clinical Features, Pathogenesis, Management

2020 ◽  
pp. 185-192
Keyword(s):  
Optic Nerve ◽  
Retinal Detachment ◽  
Visual Impairment ◽  
Optic Disc ◽  
Clinical Features ◽  
Optic Nerve Head ◽  
Congenital Anomalies ◽  
Morning Glory ◽  
Optic Disk ◽  
Morning Glory Disc Anomaly

Congenital anomalies of the optic nerve head are a group of structural malformations of the optic nerve head and surrounding tissues, which may cause visual impairment. Retinal detachment commonly occurs in association with congenital anomalies of the optic disc, including morning glory disc anomaly, optic disc pit, optic disc coloboma, peripapillary staphyloma, and Aicardi syndrome. Notably, visual impairment and retinal detachment may not be the only problem in these patients, some of these entities will be related to neurologic and systemic features, which sometimes may be life-threatening. This review presents an overview of the clinical features of these optic disk anomalies and current therapeutic approaches for the treatment of retinal detachment associated with them.

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