scholarly journals Demographic, clinical, and socioeconomic factors associated with delayed diagnosis and management of pediatric testicular torsion in West China: a retrospective study of 301 cases in a single tertiary children’s hospital

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Chengjun Yu ◽  
Jie Zhao ◽  
Jiandong Lu ◽  
Yi Wei ◽  
Li Jiang ◽  
...  
Keyword(s):  
Logistic Regression ◽  
Retrospective Study ◽  
Socioeconomic Factors ◽  
Surgical Management ◽  
Testicular Torsion ◽  
West China ◽  
Children's Hospital ◽  
Children’S Hospital ◽  
History Of ◽  
Main City

Abstract Background To investigate the association between geographic, clinical, socioeconomic factors and delayed management of pediatric testicular torsion (TT) in West China. Methods A retrospective study was conducted on TT at Children’s Hospital of Chongqing Medical University in West China from November 2004 to December 2020. Univariate analysis and logistic regression analysis were conducted to determine the association between these factors and delayed management of TT. Results A total of 301 cases were included in this study. The misdiagnosis rate of TT in primary, secondary healthcare units and tertiary hospitals was 93.8, 71.1, and 8.9%, respectively. Approximately 26.9% of TT boys received timely surgical management (within 12 h from symptoms inset to surgery). Logistic regression analyses suggested the following factors were associated with delayed repair of TT: age less than 6 years (P = 0.001), with a history of symptoms progress (P = 0.001) or former treatment (P <0.001), absence of other diagnosis (P = 0.011) and those boys living far away from the main city zones (P <0.001). Conclusions Delayed surgical management for TT was more likely for boys with age less than 6 years, the absence of other diagnosis, with a history of former treatment or symptoms progress, and those living far away from the main city zone. To maximize the possibility of timely surgical management for TT, it is vital to strengthen the public awareness of TT and conduct continuously re-education and update physicians working at primary and secondary healthcare units.

Hormone Replacement Therapy With GnRH Agonist Pretreatment Improves Pregnancy Outcomes in Patients With Previous Intrauterine Adhesions: a Retrospective Study

2021 ◽  
Author(s):  
Meilan Mo ◽  
Qizhen Zheng ◽  
Hongzhan Zhang ◽  
Shiru Xu ◽  
Fen Xu ◽  
...  
Keyword(s):  
Logistic Regression ◽  
Retrospective Study ◽  
Pregnancy Outcomes ◽  
Preparation Method ◽  
Clinical Pregnancy ◽  
Ongoing Pregnancy ◽  
Intrauterine Adhesions ◽  
Endometrial Preparation ◽  
History Of ◽  
Early Miscarriage

Abstract Objective: This retrospective study aimed to explore the optimal endometrial preparation method in women with intrauterine adhesions (IUAs).Method: A total of 882 frozen-thawed embryo transfer (FET) cycles from patients with history of IUAs were categorized into three groups based on endometrial preparation methods: hormone replacing therapy cycle (HRT, n=636), natural cycle (NC n=174), and HRT with GnRH-a pretreatment (HRT+GnRH-a, n=72. Logistic regression was performed to investigate the association between cycle regimens and pregnancy outcomes. Subgroup analysis of IUAs combined with thin endometrium (≤7mm) was also performed.Results: HRT with GnRH-a pretreatment was associated with higher incidences of clinical pregnancy, ongoing pregnancy, and live birth, but lower early miscarriage compared with either HRT or NC. Logistic regression indicated that after controlling for potential confounders, the incidences of live birth (HRT+GnRH-a as reference; NC: aOR=0.577, 95%CI 0.304-1.093; HRT: aOR=0.434, 95%CI 0.247-0.765) and ongoing pregnancy (NC: aOR=0.614, 95%CI 0.324-1.165; HRT: aOR=0.470, 95%CI 0.267-0.829) remained significantly higher in HRT+GnRH-a compared to those in HRT, but comparable to those in NC. While there was no significant difference with respect to the clinical pregnancy rate (NC: aOR=0.695, 95%CI 0.374-1.291; HRT: aOR=0.650, 95%CI 0.374-1.127) and early miscarriage rate (NC: aOR=1.734, 95%CI 0.417-7.175; HRT: aOR=2.594, 95%CI 0.718-9.378) between groups. Subgroup analysis suggested there was no superiority of endometrial preparation method in IUAs combined with thin endometrium.Conclusion: HRT with GnRH-a pretreatment improves pregnancy outcomes in women with history of IUAs. GnRH-a may restore the endometrial receptivity in the FET cycles in IUAs.

scholarly journals Epidemiological Profile of Children Infected with Bordetella pertussis at Varela Santiago Children’s Hospital: a Retrospective Study

2017 ◽  
Vol 4 (suppl_1) ◽  
pp. S677-S677
Author(s):  
Igor Thiago Queiroz ◽  
Manuela Gomes ◽  
Gleysson Rosa ◽  
David Aronoff ◽  
A Desiree Labeaud ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Bordetella Pertussis ◽  
Children's Hospital ◽  
Children’S Hospital ◽  
Epidemiological Profile

scholarly journals Association between the use of free-of-charge intrauterine devices and a history of induced abortion: a retrospective study

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Sabina Ulbricht ◽  
Angelika Beyer ◽  
Ulrich John
Keyword(s):  
Logistic Regression ◽  
Retrospective Study ◽  
Intrauterine Device ◽  
Induced Abortion ◽  
Multivariate Model ◽  
Unemployment Benefits ◽  
Intrauterine Devices ◽  
Cross Sectional ◽  
History Of ◽  
To Receive

Abstract Background To determine whether use of intrauterine device (IUD) is influenced by a history of induced abortion and the type of contraceptives used until costs are covered. Methods We analyzed data from 301 female residents in Mecklenburg-West Pomerania, an economically challenged community. The women, aged between 20 and 35 years, were entitled to receive unemployment benefits, and had access to free-of-charge oral contraceptives, ring or IUD. Cross-sectional data were analyzed using logistic regression. Results There were 112 (37.2%) women with a history of induced abortion, and 46 (15.3%) reported exclusively using less effective contraceptives (e.g. condoms). In a univariate logistic regression, use of an IUD was associated with a history of having had an induced abortion. Furthermore, uptake of an IUD was associated with women who had, until costs were covered, exclusively choice to use less effective contraceptives (OR = 3.281, 95% CI: 1.717; 6.273). Both associations remained significant in a multivariate model. Conclusions Free contraceptives provided to women receiving unemployment benefits may increase the use of IUDs, especially among those with a history of an induced abortion and those using less effective contraceptives.

Evaluation of anti-infectives prescriptions in a pediatric hemato-oncological center: A retrospective study

2018 ◽  
Vol 25 (8) ◽  
pp. 1811-1816
Author(s):  
Boubacar BF Diop ◽  
Amine Cheikh ◽  
Houda Attjioui ◽  
Mohamed R Ajaja ◽  
Hafid Mefetah ◽  
...  
Keyword(s):  
Information System ◽  
Drug Interaction ◽  
Retrospective Study ◽  
Drug Interactions ◽  
Training Program ◽  
Bacterial Resistance ◽  
Children's Hospital ◽  
Children’S Hospital ◽  
Oncological Center

Introduction A few years after the discovery and development of anti-infectives, this therapeutic feat gave way to bacterial resistance because of the overconsumption of antibiotics, most often with unjustified prescriptions. The objective was to evaluate the compliance of the prescription of antibiotherapy in the pediatric onco-hematology unit of Rabat Children's Hospital and to determine the drug interactions. Material and methods This is a retrospective study of anti-infectives prescriptions in pediatric onco-hematology. All prescriptions containing an antibiotic or antimycotic were isolated at the end of each month for analysis according to the ANSM standard. The variables of compliance analyzed in the prescriptions were: form, indication, posology, duration of the treatment, drug interactions and number of antibiotics which were prescribed. Results The prescriptions containing at least one anti-infective were 195. All the prescriptions were in conformity with their indications; 111 (57%) of the cases were conform with respect to all criteria; 20 (12%) prescriptions were not conform in their form, 12 (6.6%) contained at least one over-dosed drug and 52 (26.7%) contained at least one under-dosed drug. A drug interaction was found in 15 (7.7%) of cases, of which 12 (6.2%) are precautions for use. A drug interaction is present in 1(6,7%) cases when a single antibiotic is prescribed against 3 (20%) cases when 4 antibiotics are prescribed. ( p = 0.007). Conclusion The number of non-compliances in our study was high. It would therefore be advisable to recommend the establishment of an information system to minimize the non-compliances and to ensure a training program for young doctors on international recommendations.

History of Fetal Diagnosis and Therapy: Children’s Hospital of Philadelphia Experience

2003 ◽  
Vol 18 (2) ◽  
pp. 65-82 ◽  
Author(s):  
Holly L. Hedrick ◽  
Alan W. Flake ◽  
Timothy M. Crombleholme ◽  
Lori J. Howell ◽  
Mark P. Johnson ◽  
...  
Keyword(s):  
Fetal Diagnosis ◽  
Children's Hospital ◽  
Diagnosis And Therapy ◽  
Children’S Hospital ◽  
History Of
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