scholarly journals Improvement of long-term risks of cardiovascular events associated with community-based disease management in Chinese patients of the Xinjiang autonomous region of China

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Yang Li ◽  
Cai Minzhang ◽  
Ma Minghui ◽  
Huang Xinmiao ◽  
Liu Laixin ◽  
...  
Keyword(s):  
Disease Management ◽  
Cardiovascular Events ◽  
Chinese Patients ◽  
Community Based ◽  
Autonomous Region ◽  
Xinjiang Autonomous Region

scholarly journals Evaluation of “Sophia Diabetes”, a diabetic patient support programme, 8 years after its initiation

2019 ◽  
Vol 29 (Supplement_4) ◽  
Author(s):  
R Cash ◽  
M Cavillon ◽  
C Leboucher ◽  
B Jouaneton ◽  
A Vainchtock ◽  
...  
Keyword(s):  
Health Insurance ◽  
Disease Management ◽  
Cardiovascular Events ◽  
Positive Impact ◽  
Management Program ◽  
First Year ◽  
Patient Support ◽  
Major Cardiovascular Events

Abstract Background “Sophia Diabetes” is a personalized diabetic patient support program piloted by French National Health Insurance, launched experimentally in 10 primary health insurance funds in March 2008, extended in 2010 and then generalized to all of France in 2012-2013. A new evaluation was performed in 2018 to determine long-term (2008-2016) improvement of medical follow-up indicators, impact on morbidity, mortality and healthcare expenditure. Methods A sample of patients (n = 49,016) eligible for the programme in 2008, but also a sub-group of participating patients (n = 17,007), was matched, using propensity score, with controls randomly selected from the SNDS. Difference in difference method was applied for comparisons at each year of follow-up (Ti) while controlling for differences between populations. Results Sophia had a significant positive impact on recommended follow-up indicators, right from the first year. This improvement was maintained for most indicators even if compliance rates remained lower than targets. Sophia Diabetes does not appear to have a major impact on hospitalization rates in either eligible patients or participating patients. However, comparison between participants and controls revealed a less marked increase of hospitalizations for major cardiovascular events at T6 and T7. Compared to their controls, a better use of hospital emergency departments was observed for participants. Ambulatory care expenditure of participants increased more markedly between T4 and T7 (+€105 to €233), related to a better follow-up but in contrast, hospital expenditure increased less markedly during the first year of follow-up (-€139) and the last 2 years (-€360 to -€380). Conclusions For the first time in France, a disease management program has been evaluated over a long period. Globally, Sophia programresults in improved patient follow-up, decreased emergency visits, and a less marked increase of hospitalizations for major cardiovascular events at the end of period. Key messages First long term evaluation (8 years) of a disease management program in France. Sophia diabetes management program shows a positive impact on some follow-up and morbidity indicators.

The Long-Term Influence of Tissue Inhibitor of Matrix Metalloproteinase-1 in Patients with Mild to Moderate Coronary Artery Lesions in a Chinese Population: A 7-Year Follow-Up Study

Cardiology ◽  
2015 ◽  
Vol 132 (3) ◽  
pp. 151-158 ◽  
Author(s):  
Wei Wang ◽  
Xiantao Song ◽  
Yundai Chen ◽  
Fei Yuan ◽  
Feng Xu ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Matrix Metalloproteinase ◽  
Chinese Population ◽  
Cardiovascular Events ◽  
Chinese Patients ◽  
Coronary Artery Lesions ◽  
Tissue Inhibitor ◽  
Matrix Metalloproteinase 1

Objectives: Matrix metalloproteinase-9 (MMP-9), tissue inhibitor of matrix metalloproteinase-1 (TIMP-1) and their ratio (MMP-9/TIMP-1) are involved in multiple processes that are associated with coronary heart disease and are especially associated with cardiovascular events. However, few long-term population-based clinical studies have evaluated the role of these factors in cardiovascular events in a Chinese population. Methods: A prospective study was performed on 560 patients with mild to moderate coronary artery lesions. MMP-9, TIMP-1 and their ratio were determined. Results: A total of 522 of patients completed the follow-up. The median follow-up time was 64 months. Kaplan-Meier analysis demonstrated a clear increase of the incidence of major adverse cardiac events (MACEs) during the follow-up period in subjects with above-median levels of TIMP-1 (p = 0.033), whereas there was no association with either MMP-9 (p = 0.199) or MMP-9/TIMP-1 (p = 0.631). Multivariate Cox proportional hazards analysis showed the same results after further adjustment for covariates. Patients with above-median levels of TIMP-1 were more likely to suffer from adverse outcomes than patients with below-median levels of TIMP-1. However, the lack of relationship of MACEs with MMP-9 and MMP-9/TIMP-1 remained. Conclusions: Higher circulating TIMP-1 concentrations were associated with cardiovascular events during long-term follow-up of Chinese patients with mild to moderate coronary artery lesions.

scholarly journals Long-Term Healthcare and Cost Outcomes of Disease Management in a Large, Randomized, Community-Based Population With Heart Failure

Circulation ◽  
2004 ◽  
Vol 110 (23) ◽  
pp. 3518-3526 ◽  
Author(s):  
Autumn Dawn Galbreath ◽  
Richard A. Krasuski ◽  
Brad Smith ◽  
Karl C. Stajduhar ◽  
Michael D. Kwan ◽  
...  
Keyword(s):  
Heart Failure ◽  
Disease Management ◽  
Community Based ◽  
Cost Outcomes

Maximizing Outcomes in Group Treatment of Aphasia: Lessons Learned From a Community-Based Center

2014 ◽  
Vol 24 (3) ◽  
pp. 100-105 ◽  
Author(s):  
Darlene Williamson
Keyword(s):  
Group Treatment ◽  
Treatment Protocol ◽  
Lessons Learned ◽  
Group Program ◽  
Community Based ◽  
Multiple Treatment ◽  
Use Of Technology ◽  
Communication Impairments ◽  
Treatment Settings

Given the potential of long term intervention to positively influence speech/language and psychosocial domains, a treatment protocol was developed at the Stroke Comeback Center which addresses communication impairments arising from chronic aphasia. This article presents the details of this program including the group purposes and principles, the use of technology in groups, and the applicability of a group program across multiple treatment settings.

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