scholarly journals Complicated Gitelman syndrome and autoimmune thyroid disease: a case report with a new homozygous mutation in the SLC12A3 gene and literature review

2018 ◽  
Vol 18 (1) ◽  
Author(s):  
Haiyang Zhou ◽  
Xinhuan Liang ◽  
Yingfen Qing ◽  
Bihui Meng ◽  
Jia Zhou ◽  
...  
Author(s):  
Zvonimir Bosnić ◽  
Blaženka Šarić ◽  
Domagoj Vučić ◽  
Božidar Kovačević ◽  
Nikica Marinić ◽  
...  

Author(s):  
K. Shivaraju ◽  
Mandhala Saikrishna ◽  
Billakuduru Srija ◽  
Akhil Aakunuri

Angioedema may be a rare condition that manifests itself by abrupt localized edema caused by the fluid outflow from blood vessels into surrounding skin and tissue. This case report presents a 54-year old male patient with chronic angioedema (lip) for one year without urticaria. Six months ago, he approached the local clinic and used regular antihistamines by the physician advice. Still, there was no improvement in patient condition. Then he came to the outpatient department of internal medicine of our hospital. Therefore, we have done a series of investigations, in then he diagnosed with Hypothyroidism (TSH 8.05UIu/ml). Then he has prescribed levothyroxine 25mcg. After one month's review, he examined for Anti-thyroid peroxidase antibodies (Anti-TPO). In that examination, those were positive or elevated (mild). According to our research, this may probably be the first autoimmune thyroid disease associated with chronic angioedema without urticaria or hives.


Cases Journal ◽  
2009 ◽  
Vol 2 (0) ◽  
Author(s):  
Imran Masood ◽  
Mir Yasir ◽  
Aiffa Aiman ◽  
R P Kudyar

Arthritis ◽  
2012 ◽  
Vol 2012 ◽  
pp. 1-15 ◽  
Author(s):  
Jorge Cárdenas Roldán ◽  
Jenny Amaya-Amaya ◽  
Juan Castellanos-de la Hoz ◽  
Juliana Giraldo-Villamil ◽  
Gladys Montoya-Ortiz ◽  
...  

Objective. To determine the prevalence and impact of autoimmune thyroid disease (AITD) in patients with rheumatoid arthritis (RA). Methods. Eight-hundred patients were included. The association between AITD and RA was analyzed was analyzed by bivariate and multivariate analysis. In addition, a literature review was done focusing on geographical variations. Results. In our cohort the prevalence of AITD was 9.8% while the presence of antibodies was 37.8% for antithyroperoxidase enzyme (TPOAb) and 20.8% for antithyroglobulin protein (TgAb). The presence of type 2 diabetes, thrombosis, abnormal body mass index, and a high educational level was positively associated with AITD. The literature review disclosed a geographical variation of AITD in RA ranging from 0.5% to 27%. Autoantibody prevalence ranges from 6% to 31% for TgAb, 5% to 37% for TPOAb, and from 11.4% to 32% for the presence of either of the two. Conclusion. AITD is not uncommon in RA and should be systematically assessed since it is a risk factor for developing diabetes and cardiovascular disease. These results may help to further study the common mechanisms of autoimmune diseases, to improve patients’ outcome, and to define public health policies. An international consensus to accurately diagnose AITD is warranted.


2015 ◽  
Vol 02 (02) ◽  
pp. 76-80
Author(s):  
Lisandra Damian ◽  
Maria Christina Ungureanu ◽  
Cristina Mihaela Ghiciuc ◽  
Francesca Romana Patacchioli ◽  
Lucia Corina Dima-Cozma ◽  
...  

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