scholarly journals Porcine Mx1 fused to HIV Tat protein transduction domain (PTD) inhibits classical swine fever virus infection in vitro and in vivo

2015 ◽  
Vol 11 (1) ◽  
Author(s):  
Xiaomin Zhang ◽  
Jiao Jing ◽  
Wenliang Li ◽  
Ke Liu ◽  
Baojun Shi ◽  
...  
Keyword(s):  
Virus Infection ◽  
Classical Swine Fever Virus ◽  
Classical Swine Fever ◽  
Protein Transduction ◽  
Protein Transduction Domain ◽  
Tat Protein ◽  
Hiv Tat ◽  
Hiv Tat Protein

Getting to grips with the granulocyte: manipulation of granulocyte behaviour and apoptosis by protein transduction methods

2004 ◽  
Vol 32 (3) ◽  
pp. 452-455 ◽  
Author(s):  
A.G. Rossi ◽  
C. Ward ◽  
I. Dransfield
Keyword(s):  
Recent Literature ◽  
Inflammatory Diseases ◽  
Protein Transduction ◽  
Biological Processes ◽  
Tat Protein ◽  
Hiv Tat ◽  
Human Granulocytes ◽  
Hiv Tat Protein ◽  
Functional Responsiveness

Human granulocytes clearly play an important role in host defence against invading organisms, however they have also been implicated in the pathogenesis and progression of many chronic inflammatory diseases. In addition, these cells have been paramount in gaining a better understanding of many key-signalling pathways regulating fundamental biological processes. Since granulocytes are terminally differentiated and undergo relatively rapid constitutive apoptosis it has been difficult to manipulate intracellular events by transfection or transduction procedures. It has been shown in recent years that the HIV-TAT protein transduction system can be successfully used in granulocytes to manipulate key signalling mechanisms regulating functional responsiveness and survival. In this paper, we review recent literature highlighting important developments using this system in isolated human granulocytes and in inflammatory process in vivo where these cells play a prominent role.

scholarly journals HIV-Tat protein transduction domain specifically attenuates growth of polyamine deprived tumor cells

2007 ◽  
Vol 6 (2) ◽  
pp. 782-788 ◽  
Author(s):  
Katrin Mani ◽  
Staffan Sandgren ◽  
Johanna Lilja ◽  
Fang Cheng ◽  
Katrin Svensson ◽  
...  
Keyword(s):  
Tumor Cells ◽  
Protein Transduction ◽  
Protein Transduction Domain ◽  
Tat Protein ◽  
Hiv Tat ◽  
Hiv Tat Protein ◽  
Tat Protein Transduction Domain

scholarly journals Immunological properties of recombinant classical swine fever virus NS3 protein in vitro and in vivo

2006 ◽  
Vol 37 (1) ◽  
pp. 155-168 ◽  
Author(s):  
Henriette Rau ◽  
Hilde Revets ◽  
Carole Balmelli ◽  
Kenneth C. McCullough ◽  
Artur Summerfield
Keyword(s):  
Classical Swine Fever Virus ◽  
Classical Swine Fever ◽  
Fever Virus ◽  
Immunological Properties ◽  
Ns3 Protein
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