scholarly journals Increased aortic intima-media thickness may be used to detect macrovascular complications in adult type II diabetes mellitus patients

2018 ◽  
Vol 16 (1) ◽  
Author(s):  
Ayse Selcan Koc ◽  
Hilmi Erdem Sumbul
2021 ◽  
Vol 59 (244) ◽  
pp. 1243-1246
Author(s):  
Prakash Kayastha ◽  
Sharma Paudel ◽  
Ghanshyam Gurung ◽  
Pradeep Kumar ◽  
Rudra Prasad Upadhyaya ◽  
...  

Introduction: Sonographic carotid intima media thickness measurement in diabetic patients is an important tool for estimating the risk of cardiovascular and cerebrovascular events. It is a simple, noninvasive and widely available tool which can give idea of further treatment needed. The objective of this study was to determine the mean intima media complex thickness in patients with type II diabetes mellitus attending a tertiary care center. Methods: This was a descriptive cross-sectional study done in 64 patients with the type II diabetes mellitus patients visiting diabetic clinic of Tribhuvan University Teaching Hospital, sent for carotid Doppler examination in the department of radiology and imaging. Ethical approval was taken from the Instituitonal Review Board. Convenient sampling method was used. Carotid intima media thickness was measured on both sides and mean intima media thickness was calculated. Mean intima media thickness for male and female diabetic patients was also calculated separately. Statistical Package for Social Sciences version 25 was used for data analysis. Results: The mean carotid intima media thickness was 0.86±0.13mm with range from 0.7mm to 1.3mm. Mean intima media thickness in male was 0.832±0.094mm and in female it was 0.904±0.144mm. Among 64 patients, 30 (46.8%) were female and 34 (53.3%) were male. Age of the patients ranged from 35 years to 68 years with mean age of 52.4±6.54 years. Conclusions: Carotid intima media thickness in patients with type II diabetes mellitus showed higher values than that of mean value from study done in similar study. Female had higher mean intima media thickness than male.


2017 ◽  
Vol 3 (1) ◽  
pp. 15-19
Author(s):  
Anita Bhosale ◽  
MV Krishna ◽  
Suraj Das ◽  
M Gautam

ABSTRACT Background The present study was carried out to study various atherosclerotic risk factors in prediabetes and type II diabetes mellitus (DM) patients, with special reference to carotid artery intima–media thickness (CIMT). The mean value of CIMT as an indicator of early atherosclerosis was determined and the various atherosclerotic risk factors in patients with prediabetes and type II DM were studied. Materials and methods A Comparative two group study was conducted involving 50 patients each with prediabetes and type 2 diabetes mellitus in the age group of 30 to 65 years, Confirmed by FPG/2hour PG/HbA1C/Random plasma glucose values according to ADA criteria, over a period of one year. The study consisted of interview regarding demographic profiles, vascular risk factors, fundoscopy and investigation like FPG, 2hour PG with OGTT, HbA1C, lipid profile, Renal function tests, urine for microalbuminuria, ECG, 2DECHO and CIMT Measurement using B mode ultrasonography. Results The association between age of the patients and occurrence of type II DM and prediabetes was found to be statistically significant. Mean duration of type II DM in our study was 6.64 ± 6.71 years. 66% Diabetics and 62% Pre-Diabetics had a BMI over 23. Mean TGs levels in diabetics and Pre-diabetics where 268 mg/dl and 193mg/dl respectively. Mean CIMT in Diabetics and Pre-diabetics were 0.81mm and 0.67mm respectively. Incidence of hypertension in diabetics and Pre-diabetics were 30% and 26% respectively. CIMT had a positive association with hypertension, smoking, and a moderate significance with alcohol use. Conclusion The present study emphasizes on the role of CIMT measurement as a routine investigation among diabetics and pre-diabetics for early recognition of atherosclerosis and cardiovascular risk reduction. How to cite this article Bhosale A, Krishna MV, Suraj D, Gautam M. Study of Atherosclerotic Risk Factors in Patients with Prediabetes and Type II Diabetes Mellitus with Special Reference to Carotid Intima–media Thickness. J Med Sci 2017;3(1):15-19.


2021 ◽  
Vol 11 (01) ◽  
pp. 27-30
Author(s):  
Sadia Shahid ◽  
Abdul Latif Khattak ◽  
Karamat Hussain Shah Bukhari ◽  
Raffi Uddin ◽  
Raees Iqbal Khan ◽  
...  

Objectives: To assess Carotid artery intima-media thickness in patients with type II diabetes mellitus. Study design and setting: This descriptive cross-sectional study was conducted at Department of Medicine, CMH Quetta from June 2018 to May 2019. Methodology: Total 176 known type II diabetes mellitus (DM) patients were included in study. Age ranged from 30-70 years. Patients using statin drugs, chronic kidney disease and decompensated liver cirrhosis were excluded. Carotid artery ultrasonography was carried out by radiologist. Carotid artery intima-media thickness (CIMT) was achieved with a 7 MHz B-mode ultrasound system. The intima-media thickness (IMT) was demarcated as the distance between the leading edge of the luminal echo to the leading edge of the adventitia of the media. This distance was measured during the diastolic phase. This was measured 3 cm before the carotid bifurcation. Also, carotid bifurcation and internal carotid artery 2 cm distally from the carotid bifurcation was scanned. Results: Mean age was 47.86 ± 6.46 years. Most of the patients 125 (71.02%) were consisted of 30 to 50 years of age. Among them the 176 patients, 92 (52.27%) were male and 84 (47.73%) were females. Male to female ratio comprised of 1.1:1. Results further revealed that 43(24.43%) patients showed asymptomatic Carotid artery intima-media thickness. Rest there was no asymptomatic Carotid artery intima-media thickness in 133 (75.57%) patients. Conclusion: This study determined that the frequency of asymptomatic Carotid artery intima-media thickness in patients with type II diabetes mellitus is quite high.


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